305
Views
5
CrossRef citations to date
0
Altmetric
Original Article

External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia

, , , , , , , , , , , & show all
Pages 265-276 | Published online: 06 Jan 2014
 

Abstract

Objective: To validate a previously published prediction model for recurrent early-onset preeclampsia (PE). Methods: We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model. Results: Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45–73). The model created groups that were only moderately different in terms of their risk. Conclusions: The model’s discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.

Acknowledgements

We thank research nurses, research midwives, and administrative assistants of the Consortium for women's health and reproductivity studies, and the residents, nurses, midwives, and gynaecologists of the participating centres for their help with participant recruitment and data collection.

Ethical approval

This study has been approved by the ethical committee of the University Hospital Maastricht (Ref.no. MEC 07-2-078). A total of six academic and three non-academic hospitals participated in this study; all of them have completed their obligatory feasibility assessment procedure successfully.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.