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Original Articles

Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia

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Pages 204-208 | Published online: 16 Mar 2015
 

Abstract

Objective: Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA). Methods: IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns. IMA was estimated colorimetrically and the results were compared statistically. Results: The levels of IMA were found to be significantly higher (p < 0.001) in newborns born to pre-eclamptic mothers (0.835 ± 0.02 ABSU) as compared to those born to normal mothers (0.325 ± 0.01 ABSU). Conclusion: IMA may act as a marker of ischemia and oxidative stress in newborns delivered to pre-eclamptic mothers.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.

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