Inhibition of Na/K ATPase Activity in Maternal and Neonatal Erythrocyte Ghosts in Pregnancy-Induced Hypertension

Andrea L. Tranquilli Department of Obstetrics and Gynecology, Universitiy of Ancona, 60123, Ancona, Italy

Laura Mazzanti Department of Biochemistry, Universitiy of Ancona, 60123, Ancona, Italy

Angela Ancona Department of Obstetrics and Gynecology, Universitiy of Ancona, 60123, Ancona, Italy

Sabina Brandi Department of Obstetrics and Gynecology, Universitiy of Ancona, 60123, Ancona, Italy

Enrico Bertoli Department of Biochemistry, Universitiy of Ancona, 60123, Ancona, Italy

Carlo Romanini Department of Obstetrics and Gynecology, Universitiy of Ancona, 60123, Ancona, Italy

Abstract

The specific activity of Na/K ATPase was determined to investigate the Sodium pump, in pregnancy-induced hypertension. A slight significant reduction in pump activity was observed in pregnancy induced hypertensive patients. A similar trend was shown in cord blood from pregnancy-hypertensive mothers, although not statistically significant. This reduction could explain the finding of higher intracellular Sodium levels in pregnancy-induced hypertension.

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Inhibition of Na/K ATPase Activity in Maternal and Neonatal Erythrocyte Ghosts in Pregnancy-Induced Hypertension

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Inhibition of Na/K ATPase Activity in Maternal and Neonatal Erythrocyte Ghosts in Pregnancy-Induced Hypertension

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