Do Nondipping Pattern and Metabolic Syndrome Impact Left Ventricular Geometry and Global Function in Hypertensive Patients?

Abstract

The aim of this study was to investigate the impact of nondipping arterial blood pressure pattern and the metabolic syndrome (MS), as well as their interaction, on left ventricular (LV) structural and function remodeling. The study included 352 never-treated hypertensive patients with and without MS. Nondipping pattern and MS, separately, as well as their interaction, significantly impacted LV structure, LV geometry pattern, systolic, diastolic and global function in hypertensive patients. Abdominal obesity was the only MS criterion which was simultaneously associated with LV hypertrophy, LV diastolic dysfunction and, LV global dysfunction.

• metabolic syndrome
• ambulatory blood pressure monitoring
• nondipping
• left ventricle
• hypertrophy
• diastolic dysfunction