Management of Hypertension in Pregnancy

Abstract

Hypertension in pregnancy is generally defined as either an absolute BP ≥ 140/90 mm Hg or a rise in systolic BP ≥25 mm Hg and/or diastolic BP ≥15 mm Hg from pre-conception or 1^st trimester BP. Hypertension in pregnancy is classified as: a) Chronic—essential or secondary hypertension, b) De novo—pre-eclampsia or gestational hypertension, and c) Pre-eclampsia superimposed on chronic hypertension. Pre-eclampsia is a multisystem disorder in which hypertension is but one sign. The major maternal abnormalities occur in kidneys, liver, brain and coagulation systems Impaired uteroplacentai blood flow causes fetal growth retardation or intraurerine death. There is general agreement that BP ≥ 170/11C mm Hg should be lowered rapidly to protect the mother against risk of stroke or eclampsia. There is dispute concerning the level at which lesser degrees of hypertension should be treated, and lowering BP is treating only one aspect of pre-eclampsia. Delivery remains the definitive management.

Key Words:

• pre-eclampsia
• eclampsia
• white–coat Hypertension
• gestational hypertension
• placenta
• methyldopa
• oxprenolol
• hydralazine
• magnesium
• volume expansion