Dendrimers – from organic synthesis to pharmaceutical applications: an update

Abstract

Dendrimers are a relatively new class of monodisperse polymers, which have tree-like spherical structures with well-defined sizes and shapes. Their unique structure has a significant impact on their physical and chemical properties. Research on dendrimers is of significant interest to scientists from all areas and their utility in various scientific fields, including pharmaceuticals, is expanding. The present review is comprehensive and covers different aspects of dendrimers viz. (1) synthesis, (2) properties and (3) pharmaceutical applications. The emphasis is on their applications as well as the current ongoing research status for drug targeting.

• Dendrimer classification
• drug delivery
• spherical polymers

Acknowledgements

Ms Carrin Martin in acknowledged for proof reading of the paper.

Declaration of interest

The authors report no declarations of interest. Rahul S. Kalhapure is thankful to University Grants Commission, Government of India under UGC-SAP, National Research Foundation of South Africa and University of KwaZulu-Natal for financial support.