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Biomarkers Volume 18, 2013 - Issue 4
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Short Communication

Long-term stability of biomarkers of the iron status in human serum and plasma

Eugène H. J. M. JansenCentre for Health Protection, National Institute of Public Health and the Environment BilthovenThe NetherlandsCorrespondence[email protected]
,
Piet K. BeekhofCentre for Health Protection, National Institute of Public Health and the Environment BilthovenThe Netherlands
&
Erna SchenkCentre for Health Protection, National Institute of Public Health and the Environment BilthovenThe Netherlands
Pages 365-368 | Received 21 Feb 2013, Accepted 26 Feb 2013, Published online: 29 Apr 2013
 
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Abstract

Context: In epidemiological research, it is very important to test the stability of biomarkers as function of both storage time and temperature.

Objective: In this study, the stability of biomarkers of the iron status was tested up to 1 year of storage.

Materials and methods: The biomarkers include total iron, unsaturated iron binding capacity, ferritin, transferrin, soluble transferrin receptor, ceruloplasmin and haptoglobin.

Results: The concentrations of all biomarkers tested remain constant upon storage at −20, −70 and −196 °C.

Conclusion: All biomarkers of the iron status were stable at the temperatures tested for 1 year.

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