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Biomarkers Volume 18, 2013 - Issue 8
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Research Article

The association between galectin-3 and occurrence of reinfarction early after first myocardial infarction treated invasively

Iwona SzadkowskaDepartment of Internal Diseases and Cardiological RehabilitationCorrespondence[email protected]
,
Rafal Nikodem WlazelDepartment of Laboratory Diagnostics and Clinical Biochemistry
,
Marta MigalaDepartment of Intensive Cardiac Therapy
,
Karolina Bajon-LaskowskaDepartment of Internal Diseases and Cardiological Rehabilitation
,
Krzysztof SzadkowskiDepartment of Food, Hygiene and Epidemiology, Medical University of Lodz LodzPoland
,
Marzenna ZielińskaDepartment of Intensive Cardiac Therapy
,
Marek ParadowskiDepartment of Laboratory Diagnostics and Clinical Biochemistry
&
Lucjan PawlickiDepartment of Internal Diseases and Cardiological Rehabilitation
 show all
Pages 655-659 | Received 02 Aug 2013, Accepted 31 Aug 2013, Published online: 08 Oct 2013
 
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Abstract

Context: Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease.

Objective: The study aimed to assess the relationship between galectin-3 levels and the occurrence of reinfarction early after myocardial infarction (MI).

Methods: The study included 145 consecutive patients with first MI treated invasively. Serum galectin-3 was measured using VIDAS (bioMérieux, Marcy-l'Etoile, France).

Results: The independent predictors of reinfarction in our group were as follows: female gender, elevated hs-C-reactive protein and galectin-3 levels (measured both at discharge).

Conclusions: Galectin-3 might be an additional useful biomarker in prediction for reinfarction early after first MI.

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