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Review Article

Biomarkers as outcome predictors in subarachnoid hemorrhage – a systematic review

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Pages 95-108 | Received 17 Nov 2013, Accepted 06 Jan 2014, Published online: 05 Feb 2014
 

Abstract

Context: Subarachnoid hemorrhage (SAH) has a high fatality rate and many suffer from delayed neurological deficits. Biomarkers may aid in the identification of high-risk patients, guide treatment/management and improve outcome.

Objective: The aim of this review was to summarize biomarkers of SAH associated with outcome.

Methods: An electronic database query was completed, including an additional review of reference lists to include all potential human studies.

Results: A total of 298 articles were identified; 112 were reviewed; 55 studies were included.

Conclusion: This review details biomarkers of SAH that correlate with outcome. It provides the basis for research investigating their possible translation into the management of SAH patients.

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