Advanced search
Publication Cover
Biomarkers Volume 19, 2014 - Issue 3
Submit an article Journal homepage
144
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Is Symmetric Dimethylarginine a sensitive biomarker of subclinical kidney injury in children born with low birth weight?

Piotr Tomasz ProtasDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPolandCorrespondence[email protected]
,
Edyta Tenderenda-BanasiukDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPoland
,
Katarzyna Taranta-JanuszDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPoland
,
Renata FiłonowiczDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPoland
,
Magdalena ZającDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPoland
&
Anna WasilewskaDepartment of Pediatric Nephrology, Medical University of Bialystok BialystokPoland
Pages 231-235 | Received 21 Dec 2013, Accepted 25 Feb 2014, Published online: 28 Mar 2014
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Objective: The aim of this study was to investigate if Symmetric Dimethylarginine (SDMA) is a sensitive biomarker of renal function and may predict subclinical kidney injury in low birth weight (LBW) children.

Methods: We studied 68 LBW children and 20 children as reference group. An enzyme-linked immunosorbent assay was used to measure serum SDMA and Cystatin C (Cys C).

Results: SDMA levels were higher in study groups compared to reference groups. There was a strong correlation between SDMA and Cys C, also SDMA negatively correlated with eGFR.

Conclusion: Elevated SDMA concentration may play an important role in pathogenesis of chronic kidney disease.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 527.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.