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Abstract
Context: Nesfatin-1 is implicated to possess an anti-inflammatory effect.
Objective: The aim of our study is to investigate whether abnormal serum levels of nesfatin-1 are associated with the presence and severity of preeclampsia.
Methods: A total of 120 women with preeclampsia and 92 women with uncomplicated pregnancies were enrolled in this study.
Results: Women with preeclampsia showed significantly reduced levels of serum nesfatin-1 levels than women with uncomplicated pregnancies. Serum nesfatin-1 levels were significantly decreased in women with severe preeclampsia compared with women with mild preeclampsia.
Conclusion: Decreased serum nesfatin-1 levels are associated with the presence and severity of preeclampsia.