Abstract
Cutaneous Alternaria spp. infections occur mainly in immunosuppressed patients and itraconazole is considered as the drug of choice. We report the case of a 64-year-old heart transplanted female patient with multiple cutaneous lesions caused by Alternaria infectoria. Treatment with posaconazole resulted in complete recovery. Due to lower minimal inhibitory concentrations, better distribution and less drug interactions than with itraconazole, posaconazole may become the antifungal drug to consider in the management of cutaneous infections caused by Alternaria spp. in solid organ transplant recipients.
Acknowledgements
We are grateful to Dr Ngoc Tram To from the Cardiology Unit at Marie Lannelongue hospital (Le Plessis Robinson, France) for the patient's follow-up.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
This paper was first published online on Early Online on 5 December 2011.