CSP typing of Chinese Aspergillus fumigatus isolates: identification of additional CSP types

Abstract

Cell surface protein (CSP) typing is a typing strategy that employs comparative DNA sequence analysis of the 12-mer tandem repeat region of the AFUA_3G08890 gene. The CSP typing scheme and modified nomenclature was applied to a collection of 162 clinical Aspergillus fumigatus isolates from China. A total of 16 CSP variants were observed, including five that were newly reported, indicating that phylogeographic differences may exist between the Chinese and the previously studied Australian, European and North American A. fumigatus populations. However, the most common CSP variants observed in this study are consistent with those in previous studies.

Keywords:

• Aspergillus fumigatus
• molecular typing
• CSP typing

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and the writing of the paper.

This work was supported by the Health Ministry affiliated hospital 2010–2012 clinical key project fund.