Is HbA1c a risk factor for type 2 diabetic subjects without macro and micro vascular complications?

Abstract

Objective: Our study attempted to evaluate the diagnostic value of HbA1c in predicting diabetic dyslipidemia and cardiovascular diseases (CVD).

Methods: Study comprised 229 subjects (156 males and 73 females) with diabetic dyslipidemia without any micro and macro vascular disorders. Fasting blood samples were taken to analyse biochemical parameters like HbA1c, sugar and lipid profile.

Results: The HbA1c levels did not differ much between males (6.96 ± 1.11) and females (7.01 ± 1.19). HbA1c demonstrated a positive significant correlation with cholesterol, LDL and a negative significant correlation with HDL. Patients with HbA1c >7.0% had significantly higher value of cholesterol, LDL when compared with <7.0%.

Conclusions: The findings of this study clearly suggest that HbA1c endures the ability of predicting CVD risk in the diabetic patients without any micro and macro vascular disorder. Therefore study recommends using HbA1c as a marker for predicting the risk of developing CVD.

Keywords::

• Glycated haemoglobin
• dyslipidemia
• lipid profile

Acknowledgement

We would like to express our gratitude to Dr. G.S. Chandrashekar, Senior Physician & Cardio Diabetologist of Adarsha Hospital & Institute of Cardio diabetes, Trauma & Joint Replacement, Udupi, Karnataka for his support in conducting this study.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.