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Abstract
Background and aims: Although studies of quality of life have been conducted in patients with substance use disorder, they have seldom compared impairment in quality of life across different substances. This study aimed to compare the quality of life in men with alcohol or opioid dependence to that of their relatives in North India.
Methods: The present cross-sectional study compared 50 each alcohol- and opioid-dependent men with 30 control relatives who were not substance users. Quality of life was measured using WHO-QOL-Bref. Linear regression analysis was performed to control for variation across the three groups.
Results: Quality of life was significantly poorer in the domains of physical health, psychological health and social relationships in both alcohol- and opioid-dependent men as compared to that of their relatives (F = 9.637, p < 0.001; F = 4.030, p = 0.020 and F = 10.663 p < 0.001; respectively). No significant differences emerged between the three groups on the environmental domain (F = 1.748, p = 0.178). Linear regression models revealed alcohol and opioid dependence to be independent predictors of physical, psychological and environmental quality of life domains.
Conclusions: Several domains of quality of life are poorer in alcohol- and opioid-dependent men in northern India as compared to their relatives.
Declaration of interest
The authors declare no conflicts of interest. The work has not been previously published or is under active consideration elsewhere.