Maternal serum inhibin-A for predicting preeclampsia

Abstract

Objective. To evaluate the use of late first trimester maternal serum inhibin-A concentrations in prediction of preeclampsia.

Design. Prospective study.

Setting. Tanta University Hospital.

Methods. All cases (327) were subjected to complete history taking, clinical and ultrasound examination, CBC, liver function tests, estimation of 24 h urine protein and venous blood samples were taken during the late first trimester for estimation of serum level of inhibin-A.

Results. First trimester maternal serum inhibin-A concentrations were significantly higher in women who subsequently develop preeclampsia than the corresponding values in healthy matched control pregnant women.

Conclusions. Measurement of inhibin-A during late first trimester of pregnancy can be useful in the prediction of preeclampsia.

Keywords:

• Inhibin-A
• preeclampsia
• prediction of preeclampsia
• birth weight

Declaration of interest: The author reports no conflicts of interest. The author alone is responsible for the content and writing of the paper.