Pain and Palliative Care Pharmacotherapy Literature Summaries and Analyses

ABSTRACT

Timely and important studies are reviewed and commentaries provided by leading palliative care clinicians. Symptoms, interventions, and treatment-related adverse events addressed in this issue are effective management of cancer pain; validity of multiple self-reported pain assessment scales in medically ill populations; sleep duration and mortality in older adults; depression and survival in metastatic breast cancer patients; safety and effectiveness of tanezumab for osteoarthritis pain of the knee; and plotting the functional trajectory of certain patients with end-stage renal disease.

KEYWORDS :

• affective illness
• end-stage renal disease
• nociceptor sensitization
• pain
• pain assessment
• palliative care
• self-reported pain
• sleep
• mortality
• tanezumab.

Notes

* TRPVI also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene. It was the first isolated member of the transient receptor potential vanilloid receptor proteins which in turn are a sub family of the transient receptor potential protein group.