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Electromagnetic Biology and Medicine Volume 28, 2009 - Issue 3
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Research Article

The Comparison of Methods for Determination of Humoral and Cell-Mediated Immunity in Patients with Breast Cancer

M. NEDBALOVÁ Institute of Physiology, 1st Faculty of Medicine, Charles University, Prague, Czech RepublicCorrespondence[email protected]
,
S. TROJAN Institute of Physiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
,
A. DOHNALOVÁ Institute of Physiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
&
A. JANDOVÁ Institute of Photonics and Electronics, Academy of Sciences, Prague, Czech Republic
Pages 233-239 | Published online: 14 Dec 2009
 
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Abstract

We observed the immunological answer to antigens obtained from the human malignant breast tumor and from the blood of inbred mice strain C3H/H2K infected by LDH virus. We compared the modified ELISA method for humoral immunity with the leukocyte adherence inhibition (LAI) assay for cell-mediated immnunity. The modified ELISA method is suitable for early diagnosing and monitoring antibodies in a malignant breast tumor simultaneously with senological examinations which include mammography and clinical examinations, because the antibodies are determined in a high number of samples by single application.

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