Calculation of Externally Applied Electric Field Intensity for Disruption of Cancer Cell Proliferation

Abstract

It is already known that electrostatic, magnetostatic, extremely low-frequency electric fields, and pulsed electric field could be utilized in cancer treatment. The healing effect depends on frequency and amplitude of electric field. In the present work, a simple theoretical model is developed to estimate the intensity of electrostatic field that damages a living cell during division. By this model, it is shown that magnification of electric field in the bottleneck of dividing cell is enough to break chemical bounds between molecules by an avalanche process. Our model shows that the externally applied electric field of 4 V/cm intensity is able to hurt a cancer cell at the dividing stage.

Keywords:

• Cancer treatment
• Static electric field
• Cell modelling

Acknowledgment

The authors would like to thank Prof. Gheorghe Vasaru, Chairman of Infovision S.R.L. – Romania, for his sponsorship throughout this research work.

Declaration of Interest: The manuscript “Calculation of externally applied electric field intensity for disruption of cancer cell proliferation” is a joint work by Dr. Dariush Sardari, PhD in Physics, and Dr. Nicolae Verga, PhD in medical sciences. The first idea was given by N. Verga; the modeling and calculation work was done by D. Sardari. The work was supported partially by Infovision consulting S.R.L., Cluj – Romania, headed by Prof. Gheorghe Vasaru.