Treatment of Severe Thallium Intoxication

Manu L.N.G. Malbrain Department of Nephrology-Hypertension and Medical Intensive Therapy Unit, A.Z. Stuivenberg, Antwerpen, Belgium

Guy L.Y. Lambrecht Department of Nephrology-Hypertension and Medical Intensive Therapy Unit, A.Z. Stuivenberg, Antwerpen, Belgium

Erik Zandijk Department of Nephrology-Hypertension and Medical Intensive Therapy Unit, A.Z. Stuivenberg, Antwerpen, Belgium

Paul A. Demedts Laboratory of Clinical Chemistry and Toxicology, A.Z. Middelheim, Antwerpen, Belgium

Hugo M. Neels Laboratory of Clinical Chemistry and Toxicology, A.Z. Middelheim, Antwerpen, Belgium

Willy Lambert Laboratory of Toxicology F.F.W., Gent, Belgium

André P. De Leenheer Laboratory of Toxicology F.F.W., Gent, Belgium

Robert L. Lins Department of Nephrology-Hypertension and Medical Intensive Therapy Unit, A.Z. Stuivenberg, Antwerpen, Belgium

Ronny Daelemans Department of Nephrology-Hypertension and Medical Intensive Therapy Unit, A.Z. Stuivenberg, Antwerpen, Belgium

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Abstract

Case Report: We report a successfully treated case of severe thallium intoxication. In spite of very high serum thallium (5,240 μg/L), symptomatology was minor and recovery complete. Russian Blue was administered, diuresis was enhanced by intravenous fluids and a prolonged hemodialysis was started early. High blood flows (300 mL/min) and intravenous potassium chloride supplements, to mobilize thallium from the tissues, resulted in good clearances (96 to 150 mL/min). In order to prevent the well known complications, we recommend aggressive treatment of severe thallium intoxication

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Treatment of Severe Thallium Intoxication

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Treatment of Severe Thallium Intoxication

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