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Cutaneous and Ocular Toxicology Volume 31, 2012 - Issue 1
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Case Reports

Generalized pustular eruptions due to terbinafine

Gunseli OzturkEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
,
Bengu Gerceker TurkEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
,
Nezih KaracaOkmeydani Education And Research Hospital, Department of Dermatology, Okmeydani Education And Research Hospital, Department of Dermatology, Okmeydani, Sisli, Istanbul, TurkeyCorrespondence[email protected]
,
Isil Kilinc KaraarslanEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
,
Banu ErtekinEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
,
Ilgen ErtamEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
,
Alican KazandiEge University Medical Faculty, Department of Dermatology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
&
Gulsen KandilogluEge University Medical Faculty, Department of Pathology, Ege University Medical Faculty Department of Dermatology, Bornova, Izmir, Turkey
 show all
Pages 81-84 | Received 31 May 2011, Accepted 14 Jul 2011, Published online: 02 Sep 2011
 
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Abstract

Terbinafine, a widely used antifungal agent, may rarely cause cutaneous side effects with an incidence of 2.7%. Generalized pustular eruptions are quite uncommon but severe adverse cutaneous reactions of terbinafine have been reported. The main pustular eruptions due to terbinafine include acute generalized exanthematous pustulosis and drug induced pustular psoriasis. In this report, two cases of acute generalized exanthematous pustulosis and one case of generalized pustular psoriasis triggered with terbinafine are presented.

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