Post-operative refractory cystoid macular edema in a vitrectomized eye treated with slow-release dexamethasone implant (Ozurdex)

Abstract

Introduction: The use of a slow-release dexamethasone implant (Ozurdex) for the treatment of post-operative macular edema (ME) in a vitrectomized eye has never been used before. We herein report a case of a 70-year-old woman with post-vitrectomy ME refractory to topical, sub-tenon’s and intravitreal steroid administration that responded well to the implantation of a slow-release dexamethasone implant (Ozurdex) in a previously vitrectomized eye.

Methods: Interventional case presentation.

Results: One week post-implantation, the central retinal thickness was reduced to 383 μm from 640 μm and the best corrected visual acuity (BCVA) improved to 6/36 from counting fingers (CF). At six months’ follow-up visit, the improvement of the ME was sustained as indicated by the optical coherence tomography (OCT) measurements and the BCVA remained stable. No serious topical or systemic adverse events were observed from the implantation of Ozurdex in the vitrectomized eye.

Conclusion: The use of Ozurdex in our case resulted in rapid improvement of the post-operative resistant ME. To the best of our knowledge, this is the first report in the literature demonstrating the use of the slow-release dexamethasone implant (Ozurdex) to treat post-operative ME in a vitrectomized eye.

• Dexamethasone implant
• Ozurdex
• post-operative macular edema
• vitrectomy

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.