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Acta Orthopaedica Scandinavica Volume 57, 1986 - Issue 3
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Original Article

Nutrition of cruciate ligament reconstruction by diffusion: Collagen synthesis studied in rabbits

David Amiel Division of Orthopaedic Surgery and Rehabilitation, University of California, San Diego, La Jolla California, USA
,
Wayne H. Akeson Division of Orthopaedic Surgery and Rehabilitation, University of California, San Diego, La Jolla California, USA
,
Steve Renzoni Division of Orthopaedic Surgery and Rehabilitation, University of California, San Diego, La Jolla California, USA
,
Fred Harwood Division of Orthopaedic Surgery and Rehabilitation, University of California, San Diego, La Jolla California, USA
&
Mark Abel Division of Orthopaedic Surgery and Rehabilitation, University of California, San Diego, La Jolla California, USA
Pages 201-203 | Published online: 08 Jul 2009
 
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Abstract

The reconstructed anterior cruciate ligament was studied in the rabbit using the medial third of the patellar tendon. Tritiated proline, 100 μCi/kg body weight, was injected intra-articularly to insure detection of the metabolic conversion product 3H-hydroxyproline in the avascular graft. During the immediate postoperative period, nutrients were found to derive from the synovial fluid through a process of diffusion, demonstrating that synovial nutrition occurs prior to revascularization of the graft.

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Related Research Data

Graft maturity of the reconstructed anterior cruciate ligament 6 months postoperatively: a magnetic resonance imaging evaluation of quadriceps tendon with bone block and hamstring tendon autografts
Source: Springer Science and Business Media LLC
Revascularization process of the bone--patellar tendon--bone autograft evaluated by contrast-enhanced magnetic resonance imaging 6 and 12 months after anterior cruciate ligament reconstruction.
Source: SAGE Publications
Effects of Local Administration of Vascular Endothelial Growth Factor on Properties of the in Situ Frozen-Thawed Anterior Cruciate Ligament in Rabbits
Source: SAGE Publications

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