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Acta Orthopaedica Scandinavica Volume 66, 1995 - Issue sup266
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Original Article

Hyaluronan in inflammatory joint disease

Torvard C Laurent Departments of Medical and Physiological Chemistry, BMC, Box 575, S-751 23, Uppsala, Sweden
,
J Robert E Fraser Departments of Laboratory of Fetal and Neonatal Immunology, Faculty of Veterinary Science, Melbourne University, Australia
,
Ulla B G Laurent Departments of Ophthalmology, University of Uppsala
&
Anna Engström-Laurent Departments of Rheumatology Clinic, Regional Hospital of Falun, Sweden
Pages 116-120 | Published online: 08 Jul 2009
 
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Abstract

Hyaluronan (HYA) (Laurent et al. 1992) is a linear extracellular polysaccharide found in all tissues and body fluids but in highest concentrations in loose connective tissue. It is present in synovial fluid, where it is responsible for the unique rheological properties, in cartilage, where it forms the backbone of the proteoglycan aggregates and in the synovial tissue and joint capsule. HYA is also present in muscular tissues between the muscle bundles.

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Related Research Data

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