Complete mitochondrial genome sequence and mutations of the lung carcinoma model inbred C57BL/6 mice strain

Abstract

In the present work, we undertook the complete mitochondrial genome sequencing of an important lung carcinoma model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes, and one non-coding control region (D-loop region). The mutation events were also reported.

Keywords:

• Genome
• lung carcinoma
• mitochondrion

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. This study was supported by the grants from National Natural Science Foundation of China (Nos. 30960439 and 81101693), National Key Clinical Specialty (Oncology) fund, and Yunnan National Natural Science Foundation (No. 2011FB206).