Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine

Yuki NankeInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, JapanCorrespondence[email protected]

Masako IwataniInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Tsuyoshi KobashigawaInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Toru YagoInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Hisashi YamanakaInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Shigeru KotakeInstitute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Abstract

Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of d-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiographic repair of erosions and cysts.

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Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine

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Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine

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