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Perspective

Potential Missing Steps for A Wide Use of Dried Matrix Spots in Biomedical Analysis

, &
Pages 2375-2385 | Published online: 17 Sep 2015
 

Abstract

Microsampling, mainly as DBS, has been significantly expanded in the biomedical and pharmaceutical communities in the last 10 years. In parallel, technology and methodology have evolved to overcome some of the issues associated with this sampling procedure. Despite the continuous developments and interest, only a few validated and routinely implemented clinical applications have arisen beyond the initial inborn screening. Based on the latest developments in this field, this perspective aims to discuss some of the missing steps (i.e., the habits to change, the Health Authorities acceptance and the shift for dried plasma generation), which may turn the current use of microsampling into an established and standard procedure in clinical and pharmaceutical analysis.

Disclaimer

The views expressed in this perspective are those of the authors personally and do not necessarily reflect the representative affiliation or company’s position on the subject.

Financial & competing interests disclosure

J Déglon and A Thomas are founders of the DBS System Company. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.

Acknowledgements

The authors thank W Li for critical review of the manuscript.

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