https://orcid.org/0000-0002-2551-5970
Abstract
Aim: In this study quercetin–iron complex (QFC) was synthesized, and the structural characterizations such as x-ray diffraction, field emission-scanning electron microscopy, energy-dispersive x-ray and Brunner-Emmitt-Teller adsorption–desorption isotherm analysis revealed the crystallinity state, surface morphology and nature of the adsorbing surface with surface area value. Methodology: Functional characterizations such as UV-visible spectrometric and Fourier transform infrared analysis collectively indicated the chemical changes that appeared after complex formation in terms of characteristic change in the spectrum and band position, respectively. Results: The in vitro antibacterial activity against Escherichia coli and Staphylococcus aureus has shown a dose-dependent decrease in colony count and achieved significant removal at 15 mg/ml concentration of QFC. Conclusion: The molecular docking study supports the therapeutic application of QFC.
Supplementary data
To view the supplementary data that accompany this paper please visit the journal website at:www.tandfonline.com/doi/full/10.2217/epi-2016-0184
Author contributions
All authors contributed equally to the study conception and design. Material preparation, data collection and analysis were performed by P Khagar and S Sabarathinam. The first draft of the manuscript was written by P Khagar and S sabarathinam. AV Wankhade supervised the study and performed the technological support. All authors read and approved the final manuscript.
Acknowledgments
The authors would like to thank SRM institute of science and Technology, Kattankulathur, Tamilnadu-603203 for the instrument supports.
Financial disclosure
Authors would like to acknowledge Director VNIT, Nagpur for financial assistance instrumentation facility under the DST-FIST program (project no.- SR/ FST/CSI-279/2016(c)) at Department of Chemistry, VNIT, Nagpur. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
Competing interests disclosure
The authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
Writing disclosure
No writing assistance was utilized in the production of this manuscript.