Financial & competing interests disclosure
M Hurley is funded by the Wellcome Trust by way of a Clinical Research Training Fellowship. A Smyth sits on a trial steering committee for REMPEX Pharma, advisory boards for Forest Labs and Vertex and has given a paid lecture for Gilead. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.