256
Views
4
CrossRef citations to date
0
Altmetric
Research Articles

Histopathological characteristics of breast cancer and evaluation of ER alpha and Her-2neu using immunohistochemical and RT-PCR techniquesFootnoteFootnote

, , , &
Pages 275-282 | Received 11 Sep 2013, Accepted 05 Mar 2014, Published online: 17 May 2019

References

  • S.OmarH.KhaledR.GaafarA.R.ZekryS.EissaO.ElkhatibBreast cancer in Egypt: a review of disease presentation and detection strategiesEast Mediterr Health J932003448463
  • I.A.El-AttarCancer databases in the Arab WorldEthn Dis151 Suppl 12005 S 1-3-4
  • C.U.IhemelanduL.D.LeffallJrR.L.DewittyT.J.NaabH.M.MezghebeK.H.MakambiMolecular breast cancer subtypes in premenopausal and postmenopausal African American women: age-specific prevalence and survivalJ Surg Res14312007109118
  • J.K.WienckeImpact of race/ethnicity on molecular pathways in human cancerNat Rev Cancer4120047984
  • Cancer Genome Atlas NetworkComprehensive molecular portraits of human breast tumoursNature490741820126170
  • T.SørlieC.M.PerouR.TibshiraniT.AasS.GeislerH.JohnsenGene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsProc Natl Acad Sci9820011086910874
  • V.AlmendroG.FusterHeterogeneity of breast cancer: etiology and clinical relevanceClin Transl Oncol13112011767773
  • J.RheeS.W.HanD.Y.OhJ.H.KimS.A.ImW.HanThe clinicopathologic characteristics and prognostic significance of triple-negativity in node-negative breast cancerBMC Cancer82008307
  • G.MosoyanC.NagiS.MarukianA.TeixeiraA.SimonianMultiple breast cancer cell-lines derived from a single tumor differ in their molecular characteristics and tumorigenic potentialPLoS One812013e55145
  • X.LiJ.HuangP.YiR.A.BambaraR.HilfM.MuyanSingle-chain estrogen receptors (ERs) reveal that the ER alpha/beta heterodimer emulates functions of the ER alpha dimer in genomic estrogen signaling pathwaysMol Cell Biol2417200476817694
  • J.R.GosdenP.G.MiddletonD.RoutLocalization of the human oestrogen receptor gene to chromosome 6q24–q27 by in situ hybridizationCytogenet Cell Genet1433–41986218220
  • N.R.CandelariaK.LiuC.Y.LinEstrogen receptor alpha: Molecular mechanisms and emerging insightsJ Cell Biochem201310.1002/jcb.24584 [Epub ahead of print]
  • S.GreenP.WalterV.KumarA.KrustJ.M.BornertP.ArgosHuman oestrogen receptor cDNA: sequence, expression and homology to v-erb-ANature32060581986134139
  • G.L.GreeneP.GilnaM.WaterfieldA.BakerY.HortJ.ShineSequence and expression of human estrogen receptor complementary DNAScience2314742198611501154
  • G.G.KuiperJ.A.GustafssonThe novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogensFEBS Lett410119978790
  • W.L.McGuireG.C.ChamnessS.A.FuquaEstrogen receptor variants in clinical breast cancerMol Endocrinol511199115711577
  • I.PoolaJ.AbrahamK.BaldwinIdentification of ten exon deleted ERβ mRNAs in human ovary, breast, uterus and bone tissues: alternate splicing pattern of estrogen receptor ß mRNA is distinct from that of estrogen receptor alphaFEBS Lett5161–32002133138
  • L.C.MurphyEstrogen receptor variants in human breast cancerMol Cell Endocrinol7421990 C83-C6
  • S.A.FuqaD.C.AllredR.J.AuchusExpression of estrogen receptor variantsJ Cell Biochem Suppl17G1993194197
  • C.A.EncarnacionS.A.FuquaEstrogen receptor variants in breast cancerCancer Treat Res71199497109
  • U.PfefferEstrogen receptor mRNA variants. Do they have a physiological role?Ann N Y Acad Sci7841996304313
  • Q.-X.ZhangS.G.HilsenbeckS.A.W.FuquaA.BorgMultiple splicing variants of the estrogen receptor are present in individual human breast tumorsJ Steroid Biochem Mol Biol593–41996251260
  • L.K.DiazN.SneigeEstrogen receptor analysis for breast cancer: current issues and keys to increasing testing accuracyAdv Anat Pathol12120051019
  • G.ReidS.DengerM.KosF.GannonHuman estrogen receptor-alpha: regulation by synthesis, modification and degradationCell Mol Life Sci5952002821831
  • G.FlouriotH.BrandS.DengerR.MetivierM.KosG.ReidIdentification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1EMBO J1917200046884700
  • L.LiM.P.HaynesJ.R.BenderPlasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cellsProc Natl Acad Sci USA1008200348074812
  • K.H.KimJ.R.BenderRapid estrogen receptor-mediated signaling: why is the endothelium so special?Sci STKE2882005Pe28
  • Z.WangX.ZhangP.ShenB.W.LoggieY.ChangT.F.DeuelIdentification, cloning, expression of human estrogen receptor alpha36, a novel variant of human estrogen receptor-alpha66Biochem Biophys Res Commun3364200510231027
  • P.AscenziA.BocediM.MarinoStructure–function relationship of estrogen receptor alpha and beta: impact on human healthMol Aspects Med2742006299402
  • J.W.ParkR.M.NeveJ.SzollosiC.C.BenzUnraveling the biologic and clinical complexities of HER2Clin Breast Cancer852008392401
  • C.C.BenzG.K.ScottJ.C.SarupR.M.JohnsonD.TripathyE.CoronadoEstrogen-dependent tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neuBreast Cancer Res Treat24219928595
  • M.C.GutierrezS.DetreS.JohnstonS.K.MohsinJ.ShouD.C.AllredMolecular changes in tamoxifen resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinaseJ Clin Oncol2311200524692476
  • L.CoussensT.L.Yang-FengY.C.LiaoE.ChenA.GrayJ.McGrathTyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with NEU oncogeneScience2304730198511321139
  • M.A.MolinaR.SáezE.E.RamseyM.J.Garcia-BarchinoF.RojoA.J.EvansNH (2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancerClin Cancer Res822002347353
  • G.K.ScottR.RoblesJ.W.ParkP.A.MontgomeryJ.DanielW.E.HolmesA truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cellsMol Cell Biol134199322472257
  • M.A.OwensB.C.HortenM.M.Da SilvaHER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissuesClin Breast Cancer5120046369
  • D.J.SlamonW.GodolphinL.A.JonesJ.A.HoltS.G.WongD.E.KeithStudies of the HER-2/neu protooncogene in human breast and ovarian cancerScience24449051989707712
  • E.El-AbdA.HassanW.FaiedS.ZakiA.SobhiS.El-SwedyClinical relevance of HIF-1 alpha, Cox-2, leptin, and prolactin as hypoxic markers in breast cancerAJC1142012237246
  • The Belmont Report. Ethical Principles and Guidelines for the Protection of Human Subjects of Research. The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. April 18, 1979. http://www.hhs.gov/ohrp/policy/belmont.html (accessed 28.01.14).
  • S.E.SingletaryJ.L.ConnollyBreast cancer staging: working with the sixth edition of the AJCC Cancer Staging ManualCA Cancer J Clin5620063747
  • A.SaadM.ShetaA.SobhiE.AlyE.El-AbdClinical and pathological assessment of sentinel lymph node micrometastasis in breast cancer using RT-PCRJ Egypt Soc Path25120058187
  • N.Abd EL-MoneimS.EbidA.KazemA.SaadS.MousaE.EL-ABDThe role of angiogenesis assessment in the prognosis of breast carcinoma and in the evaluation of the therapeutic effect of “shark care” drug as an angiogenesis inhibitorTurkish J cancer3832008123134
  • M.NadjiQuantitative Immunohistochemistry of estrogen receptor in breast cancer. “much ado about nothing!”Appl Immunohistochem Mol Morphol1622008105107
  • D.C.AllredJ.M.HarveyM.BerardoG.M.ClarkPrognostic and predictive factors in breast cancer by immunohistochemical analysisMod Pathol1121998155168
  • L.J.LayfieldD.GuptaE.E.MooneyAssessment of tissue estrogen and progesterone receptor levelsBreast J632000189196
  • A.RhodesB.JasaniD.M.BarnesL.G.BobrowK.D.MillerReliability of immunohistochemical demonstration of oestrogen receptors in routine practice: interlaboratory variance in the sensitivity of detection and evaluation of scoring systemsJ Clin Pathol5322000125130
  • A.M.GownCurrent issues in ER and HER2 testing by IHC in breast cancerMod Pathol21Suppl 22008S8S15
  • T.OyamaY.IshikawaM.HayashiK.ArihiroJ.HoriguchiThe effects of fixation, processing and evaluation criteria on immunohistochemical detection of hormone receptors in breast cancerBreast cancer1422007182188
  • A.L.WijayaratneD.P.McDonnellThe human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulatorsJ Biol Chem2763820013568435692
  • R.L.EckertA.MullickE.A.RorkeB.S.KatzenellenbogenEstrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift techniqueEndocrinology11421984629637
  • F.J.MonsmaJrB.S.KatzenellenbogenM.A.MillerY.S.ZieglerJ.A.KatzenellenbogenCharacterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching antiestrogenEndocrinology11511984143153
  • S.SchollM.E.LippmanThe estrogen receptor in MCF-7 cells: evidence from dense amino acid labeling for rapid turnover and a dimeric model of activated nuclear receptorEndocrinology1154198412951301
  • S.DauvoisP.S.DanielianR.WhiteM.G.ParkerAntiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnoverProc Natl Acad Sci USA899199240374041
  • J.VarayoudJ.G.RamosL.MonjeV.BosquiazzoM.Muñoz-de-ToroE.H.LuqueThe estrogen receptor UTR3 mRNA splicing variant is differentially regulated by estrogen and progesterone in the rat uterusJ Endocrinol186120055160
  • T.A.HoppS.A.FuquaEstrogen receptor variantsJ Mammary Gland Biol Neoplasia3119987383
  • R.L.BalleineS.M.HuntC.L.ClarkeCoexpression of alternatively spliced estrogen and progesterone receptor transcripts in human breast cancerJ Clin Endocr Metab844199913701377
  • E.R.LeygueP.H.WatsonL.C.MurphyEstrogen receptor variants in normal human mammary tissueJ Natl Cancer Inst8851996284290
  • P.GallacchiF.SchoumacherS.Eppenberger-CastoriE.M.Von LandenbergW.KuengU.EppenbergerIncreased expression of estrogen receptor exon-5-deletion variant in relapse tissues of human breast cancerInt J Cancer79119984448
  • A.A.DaffadaS.R.JohnstonI.E.SmithS.DetreN.KingM.DowsettExon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancerCancer Res5521995288293
  • S.G.KoehorstJ.J.CoxG.H.DonkerS.Lopes da SilvaJ.P.BurbachJ.H.ThijssenFunctional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissueMol Cell Endocrinol1011-21994237245
  • H.JiangR.TengQ.WangX.ZhangH.WangZ.WangTranscriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched normal colorectal tissuesJ Steroid Biochem Mol Biol1121–320082024
  • M.A.RunnakM.A.HazhaH.A.HeminA.A.WasanR.M.RekawtH.D.MichaelA population-based study of Kurdish breast cancer in northern Iraq: hormone receptor and HER2 status. A comparison with Arabic women and United States SEER dataBMC Womens Health12201216
  • Ismail MF, Aly MS, Khaled HM, Mohamed HM. Detection of HER-2/neu, c-myc amplification and p53 inactivation by FISH in Egyptian patients with breast cancer. Ger, Med Sci 2009;7:Doc03.
  • K.A.CroninL.C.HarlanK.W.DoddJ.S.AbramsR.Ballard-BarbashPopulation-based estimate of the prevalence of HER-2 positive breast cancer tumors for early stage patients in the USCancer Invest2892010963968
  • J.S.RossJ.A.FletcherG.P.LinetteJ.StecE.ClarkM.AyersThe Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapyOncologist842003307325
  • R.E.EllsworthD.L.EllsworthH.L.PatneyB.DeyarminB.LoveJ.A.HookeAmplification of HER2 is a marker for global genomic instabilityBMC Cancer82008297