- M. Ramsey, DNA chips: state-of-the-art, Nat. Biotechnol. 16 (1998) 40–44.
- T.G. Drummond, M.G. Hill, J. Barton, Electrochemical DNA biosensors, Nat. Biotechnol. 21 (2003) 1192–1199.
- J.J. Gooding, Electrochemical DNA hybridization biosensors, Electroanalysis 14 (2002) 1149–1156.
- E. Palecek, F. Jelen, Electrochemistry of nucleic acids and development of DNA sensors, Crit. Rev. Anal. Chem. 3 (2002) 261–270.
- J. Wang, Electrochemical nucleic acid biosensors, Anal. Chim. Acta 469 (2002) 63–71.
- K. Kerman, M. Kobayashi, E. Tamiya, Recent trends in the electrochemical DNA biosensor technology, Meas. Sci. Technol. 15 (2003) R1–R11.
- M. Egholm, O. Buchhardt, P.E. Nielsen, R.H. Berg, Peptide nucleic acids (PNA): oligonucleotide analogs with an achiral peptide backbone, J. Am. Chem. Soc. 114 (1992) 1895–1897.
- J. Wang, DNA biosensors based on peptide nucleic acid (PNA) recognition layers, Biosens. Bioelectron. 13 (1998) 757–762.
- P.E. Nielsen, M. Egholm, R.H. Berg, O. Buchhardt, Peptide nucleic acids (PNA): potential antisense and anti-gene agents, Anti-cancer Drug Des. 8 (1993) 53–63.
- D.F. Doyle, D.A. Braasch, C.G. Simmons, B.A. Janowski, D.R. Corey, Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length, Biochemistry 40 (2001) 53–64.
- M.R. Lewis, F. Jia, F. Gallazzi, Y. Wang, J. Zhang, N. Shenoy, S.Z. Lever, M. Hannink, Radiometal-labeled peptide–PNA conjugates for targeting bcl-2 expression: preparation, characterization, and in vitro mRNA binding, Bioconjugate. Chem. 13 (2002) 1176–1180.
- S. Tomac, M. Sarkar, T. Ratilainen, P. Wittung, P.E. Nielsen, B. Nordén, A. Grälund, Ionic effects on the stability and conformation of peptide nucleic acid complexes, J. Am. Chem. Soc. 118 (1996) 5544–5552.
- M. Egholm, O. Buchardt, L. Christensen, C. Behrens, S.M. Freier, D.A. Driver, R.H. Berg, S.K. Kim, B. Norden, P.E. Nielsen, PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules, Nature 365 (1993) 490–492.
- T. Ratilainen, A. Holmén, E. Tuite, P.E. Nielsen, B. Nordén, Thermodynamics of sequence-specific binding of PNA to DNA, Biochemistry 39 (2000) 7781–7791.
- M. Tomschik, F. Jelen, L. Havran, L. Trnková, P.E. Nielsen, E. Palecek, Reduction and oxidation of peptide nucleic acid and DNA at mercury and carbon electrodes, J. Electroanal. Chem. 476 (1999) 71–80.
- J. Wang, P.E. Nielsen, M. Jiang, X. Cai, J.R. Fernandes, D.H. Grant, M. Ozsoz, A. Beglieter, M. Mowat, Mismatch-sensitive hybridization detection by peptide nucleic acids immobilized on a quartz crystal microbalance, Anal. Chem. 69 (1997) 5200–5202.
- J. Wang, G. Rivas, X. Cai, M. Chicharro, C. Parrado, N. Dontha, A. Begleiter, M. Mowat, E. Palecek, P.E. Nielsen, Detection of point mutation in the p53 gene using a peptide nucleic acid biosensor, Anal. Chim. Acta 344 (1997) 111–118.
- J. Wang, E. Palecek, P.E. Nielsen, G. Rivas, X. Cai, H. Shiraishi, N. Dontha, D. Luo, P.A.M. Farias, Peptide nucleic acid probes for sequence-specific DNA biosensors, J. Am. Chem. Soc. 118 (1996) 7667–7670.
- D. Ozkan, P. Kara, K. Kerman, B. Meric, A. Erdem, F. Jelen, P.E. Nielsen, M. Ozsoz, DNA and PNA sensing on mercury and carbon electrodes by using methylene blue as an electrochemical label, Bioelectrochemistry 58 (2002) 119–126.
- P. Kara, K. Kerman, D. Ozkan, B. Meric, A. Erdem, P.E. Nielsen, M. Ozsoz, Label free and label based electrochemical detection of hybridization by using methylene blue and peptide nucleic acid probes at chitosan modified carbon paste electrodes, Electroanalysis 14 (2002) 1685–1690.
- D. Ozkan, A. Erdem, P. Kara, K. Kerman, J.J. Gooding, P.E. Nielsen, M. Ozsoz, Electrochemical detection of hybridization using peptide nucleic acids and methylene blue on self-assembled alkanethiol monolayer modified gold electrodes, Electrochem. Commun. 4 (2002) 796–802.
- K. Kerman, D. Ozkan, P. Kara, B. Meric, A. Erdem, P.E. Nielsen, M. Ozsoz, Label-free bioelectronic detection of point mutation by using peptide nucleic acid probes and methylene blue, Electroanalysis 15 (2003) 667–670.
- H. Kuhn, V.V. Demidov, J.M. Couli, M.J. Fiandaca, B.D. Gildea, M.D. Frank-Kamenetskii, Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets, J. Am. Chem. Soc. 124 (2002) 1097–1103.
- M. Komiyama, S. Ye, X. Liang, Y. Yamamoto, T. Tomita, J.-M. Zhou, H. Aburatani, PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection, J. Am. Chem. Soc. 25 (2003) 3758–3762.
- F. Höök, A. Ray, B. Nordén, B. Kasemo, Characterization of PNA and DNA immobilization and subsequent hybridization with DNA using acoustic-shear-wave attenuation measurements, Langmuir 17 (2001) 8305–8312.
- M. Uhlin, E. Hornes, O. Olsvik, Advances in Biomagnetic Separations, Eaton Publishing, Natick, 1994.
- J. Wang, A.-N. Kawde, A. Erdem, M. Salazar, Magnetic bead-based label-free electrochemical detection of DNA hybridization, Analyst 126 (2001) 2020–2024.
- J. Wang, D. Xu, A. Erdem, R. Polsky, M.A. Salazar, Genomagnetic electrochemical assays of DNA hybridization, Talanta 56 (2002) 931–938.
- E. Palecek, M. Fojta, F. Jelen, New approaches in the development of DNA sensors: hybridization and electrochemical detection of DNA and RNA at two different surfaces, Bioelectrochemistry 56 (2002) 85–90.
- G.D. Reid, D.J. Whittaker, M.A. Day, D.A. Turton, V. Kayser, J.M. Kelly, G.S. Beddard, Femtosecond electron-transfer reactions in mono- and polynucleotides and in DNA, J. Am. Chem. Soc. 124 (2002) 5518–5527.
- C. Gurtner, C.F. Edman, R.E. Formosa, M.J. Heller, Photoelectrophoretic transport and hybridization of DNA oligonucleotides on unpatterned silicon substrates, J. Am. Chem. Soc. 122 (2000) 8589–8594.
- D. Ozkan, A. Erdem, P. Kara, K. Kerman, B. Meric, J. Hassmann, M. Ozsoz, Allele-specific genotype detection of Factor V Leiden mutation from polymerase chain reaction amplicons based on label-free electrochemical genosensor, Anal. Chem. 74 (2002) 5931–5936.
- J. Sambrook, E.F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, second ed., Cold Spring Harbor, New York, 1989.
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Peptide nucleic acid modified magnetic beads for intercalator based electrochemical detection of DNA hybridization
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