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Emerging Microbes & Infections Volume 3, 2014 - Issue 1
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Original Articles

Saffold virus is able to productively infect primate and rodent cell lines and induces apoptosis in these cells

Yishi XuTemasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, Singapore;Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 117597, Singapore
,
Carla Bianca Luena VictorioTemasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, Singapore;Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 117597, Singapore
,
Qimei NgTemasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, Singapore
,
Yee Joo TanDepartment of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 117597, Singapore;Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore 138673, Singapore
&
Kaw Bing ChuaTemasek Life Sciences Laboratory, National University of Singapore, Singapore 117604, SingaporeCorrespondence[email protected]
Pages 1-8 | Received 23 Sep 2015, Accepted 02 Nov 2015, Published online: 25 Jan 2019

  • Chiu C, Greninger A, Chen E et al.Cultivation and serological characterization of a human Theiler’s-like cardiovirus associated with diarrheal disease. J Virol2010;84: 4407–4414.
  • Liang Z, Kumar AM, Jones MS, Knowles NJ, Lipton HL.Phylogenetic analysis of the species Theilovirus: emerging murine and human pathogens. J Virol2008;82: 11545–11554.
  • Zoll J, Hulshof SE, Lanke K et al.Saffold virus, a human Theiler’s-like cardiovirus, is ubiquitous and causes infection early in life. PLoS Pathog2009;5: e1000416.
  • Chiu CY, Greninger AL, Kanada K et al.Identification of cardioviruses related to Theiler’s murine encephalomyelitis virus in human infections. Proc Natl Acad Sci USA2008;105: 14124–14129.
  • Jones MS, Lukashov VV, Ganac RD, Schnurr DP.Discovery of a novel human picornavirus in a stool sample from a pediatric patient presenting with fever of unknown origin. J Clin Microbiol2007;45: 2144–2150.
  • Drexler JF, Baumgarte S, de Souza Luna LK et al.Genomic features and evolutionary constraints in Saffold-like cardioviruses. J Gen Virol2010;91: 1418–1427.
  • Casals J.Immunological characterization of Vilyuisk human encephalomyelitis virus. Nature1963;200: 339.
  • Lipton HL, Friedmann A, Sethi P, Crowther JR.Characterization of Vilyuisk virus as a picornavirus. J Med Virol1983;12: 195–203.
  • Abed Y, Boivin G.New Saffold cardioviruses in 3 children, Canada. Emerg Infect Dis2008;14: 834.
  • Drexler JF, de Souza Luna LK, Stöcker A et al.Circulation of 3 lineages of a novel Saffold cardiovirus in humans. Emerg Infect Dis2008;14: 1398.
  • Blinkova O, Kapoor A, Victoria J et al.Cardioviruses are genetically diverse and cause common enteric infections in South Asian children. J Virol2009;83: 4631–4641.
  • Nielsen ACY, Gyhrs ML, Holmes EC, Cui J.Co-circulation and persistence of genetically distinct saffold viruses, Denmark. Emerg Infect Dis2012;18: 1694.
  • Galama J, Lanke K, Zoll J, Roivainen M, van Kuppeveld F.Seroepidemiology of Saffold cardiovirus type 2. Emerg Infect Dis2011;17: 1572.
  • Chua KB, Voon K, Yu M, Ali WN, Kasri AR, Wang LF.Saffold virus infection in children, Malaysia, 2009. Emerg Infect Dis2011;17: 1562–1564.
  • Himeda T, Hosomi T, Asif N et al.The preparation of an infectious full-length cDNA clone of Saffold virus. Virol J2011;8: 110.
  • Son KN, Becker RP, Kallio P, Lipton HL.Theiler’s virus-induced intrinsic apoptosis in M1-D macrophages is Bax mediated and restricts virus infectivity: a mechanism for persistence of a cytolytic virus. J Virol2008;82: 4502–4510.
  • Norbury CJ, Hickson ID.Cellular responses to DNA damage. Annu Rev Pharmacol Toxicol2001;41: 367–401.
  • Fiers W, Beyaert R, Declercq W, Vandenabeele P.More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene1999;18: 7719.
  • Zeiss CJ.The apoptosis–necrosis continuum: insights from genetically altered mice. Vet Pathol2003;40: 481–495.
  • Kischkel F, Hellbardt S, Behrmann I et al.Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J1995;14: 5579.
  • Saelens X, Festjens N, Walle LV, van Gurp M, van Loo G, Vandenabeele P.Toxic proteins released from mitochondria in cell death. Oncogene2004;23: 2861–2874.
  • Chinnaiyan AM.The apoptosome: heart and soul of the cell death machine. Neoplasia1999;1: 5.
  • Hill MM, Adrain C, Duriez PJ, Creagh EM, Martin SJ.Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J2004;23: 2134–2145.
  • Riedl SJ, Salvesen GS.The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol2007;8: 405–413.
  • Reed LJ, Muench H.A simple method of estimating fifty per cent endpoints. Am J Epidemiol1938;27: 493–497.
  • Herrmann M, Lorenz H, Voll R et al.A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res1994;22: 5506.
  • Himeda T, Hosomi T, Okuwa T, Muraki Y, Ohara Y.Saffold virus type 3 (SAFV-3) persists in HeLa cells. PloS ONE2013;8: e53194.
  • Fan J, Son KN, Arslan SY, Liang Z, Lipton HL.Theiler’s murine encephalomyelitis virus leader protein is the only nonstructural protein tested that induces apoptosis when transfected into mammalian cells. J Virol2009;83: 6546–6553.

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