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Emerging Microbes & Infections Volume 4, 2015 - Issue 1
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Original Articles

Polyphosphate kinases modulate Campylobacter jejuni outer membrane constituents and alter its capacity to invade and survive in intestinal epithelial cells in vitro

Ruby Pina-MimbelaFood Animal Health Research Program, Ohio Agricultural Research & Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH44691, USA
,
Jesús Arcos MadridDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH43210, USA
,
Anand KumarFood Animal Health Research Program, Ohio Agricultural Research & Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH44691, USA
,
Jordi B TorrellesDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH43210, USA;Center for Microbial Interface Biology, The Ohio State University, Columbus, OH43210, USACorrespondence[email protected]
&
Gireesh RajashekaraFood Animal Health Research Program, Ohio Agricultural Research & Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH44691, USA;Center for Microbial Interface Biology, The Ohio State University, Columbus, OH43210, USACorrespondence[email protected]
Pages 1-9 | Received 06 Aug 2015, Accepted 01 Oct 2015, Published online: 25 Jan 2019

  • Coker A, Isokpehi RD, Thomas BN, Amisu KO, Obi CL.Human campylobacteriosis in developing countries. Emerg Infect Dis 2002;8: 237–243.
  • World Health Organization. The global view of campylobacteriosis, report of an expert consultation.Utrecht: WHO, 2012.Available at http://www.who.int/foodsafety/publications/foodborne_disease/global_view_campylobacterosis/en/ (accessed 17 March 2015).
  • Young NM, Brisson JR, Kelly J et al.Structure of the N-linked glycan present on multiple glycoproteins in the Gram-negative bacterium, Campylobacter jejuni. J Biol Chem 2002;277: 42530–42539.
  • Zilbauer M, Dorrell N, Elmi A et al.A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. Cell Microbiol 2007;9: 2404–2416.
  • Samuelson DR, Eucker TP, Bell JA, Dybas L, Mansfield LS, Konkel ME.The Campylobacter jejuni CiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease. Cell Commun Signal 2013;11:79.
  • Guerry P, Szymanski CM.Campylobacter sugars sticking out. Trends Microbiol 2008;16: 428–435.
  • Maue AC, Mohawk KL, Giles DK et al.The polysaccharide capsule of Campylobacter jejuni modulates the host immune response. Infect Immun 2013;81: 665–672.
  • Jahid IK, Silva AJ, Benitez JA.Polyphosphate stores enhance the ability of Vibrio cholerae to overcome environmental stresses in a low-phosphate environment. Appl Environ Microbiol 2006;72: 7043–7049.
  • Chuang YM, Belchis DA, Karakousis PC.The polyphosphate kinase gene ppk2 is required for Mycobacterium tuberculosis inorganic polyphosphate regulation and virulence. MBio 2013;4: e00039–e00113.
  • Rao NN, Gomez-Garcia MR, Kornberg A.Inorganic polyphosphate: essential for growth and survival. Annu Rev Biochem 2009;78: 605–647.
  • Castuma CE, Huang R, Kornberg A et al.Inorganic polyphosphates in the acquisition of competence in Escherichia coli. J Biol Chem 1995;270: 12980–12983.
  • Kornberg A.Inorganic polyphosphate: toward making a forgotten polymer unforgettable. J Bacteriol 1995;177: 491–496.
  • Singh R, Singh M, Arora G, Kumar S, Tiwari P, Kidwai S.Polyphosphate deficiency in Mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs. J Bacteriol 2013;195: 2839–2851.
  • Candon HL, Allan BJ, Fraley CD, Gaynor EC.Polyphosphate kinase 1 is a pathogenesis determinant in Campylobacter jejuni. J Bacteriol 2007;189: 8099–8108.
  • Gangaiah D, Kassem II, Liu Z, Rajashekara G.Importance of polyphosphate kinase 1 for Campylobacter jejuni viable-but-nonculturable cell formation, natural transformation, and antimicrobial resistance. Appl Environ Microbiol 2009;75: 7838–7849.
  • Gangaiah D, Liu Z, Arcos J et al.Polyphosphate kinase 2: a novel determinant of stress responses and pathogenesis in Campylobacter jejuni. PLoS One 2010;5: e12142.
  • Malde A, Gangaiah D, Chandrashekhar K, Pina-Mimbela R, Torrelles JB, Rajashekara G.Functional characterization of exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) of Campylobacter jejuni. Virulence 2014;5: 521–533.
  • Chakrabarty AM.Nucleoside diphosphate kinase: role in bacterial growth, virulence, cell signalling and polysaccharide synthesis. Mol Microbiol 1998;28: 875–882.
  • Karlyshev AV, Everest P, Linton D, Cawthraw S, Newell DG, Wren BW.The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology 2004;150: 1957–1964.
  • Tsai CM, Frasch CE.A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. Anal Biochem 1982;119: 115–119.
  • Yang L, Sinha T, Carlson TK, Keiser TL, Torrelles JB, Schlesinger LS.Changes in the major cell envelope components of Mycobacterium tuberculosis during in vitro growth. Glycobiology 2013;23: 926–934.
  • Shi L, Torrelles JB, Chatterjee D.Lipoglycans of Mycobacterium tuberculosis: isolation, purification, and characterization. Methods Mol Biol 2009;465: 23–45.
  • Torrelles JB, Khoo KH, Sieling PA et al.Truncated structural variants of lipoarabinomannan in Mycobacterium leprae and an ethambutol-resistant strain of Mycobacterium tuberculosis. J Biol Chem 2004;279: 41227–41239.
  • Fraley CD, Rashid MH, Lee SS et al.A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects. Proc Natl Acad Sci USA 2007;104: 3526–3531.
  • Ogawa N, Tzeng CM, Fraley CD et al.Inorganic polyphosphate in Vibrio cholerae: genetic, biochemical, and physiologic features. J Bacteriol 2000;182: 6687–6693.
  • Hickey TE, Baqar S, Bourgeois AL, Ewing CP, Guerry P.Campylobacter jejuni-stimulated secretion of interleukin-8 by INT-407 cells. Infect Immun 1999;67: 88–93.
  • Palumbo SA.Heat injury and repair in Campylobacter jejuni. Appl Environ Microbiol 1984;48: 477–480.
  • Roessler M, Sewald X, Muller V.Chloride dependence of growth in bacteria. FEMS Microbiol Lett 2003;225: 161–165.
  • Koski P, Vaara M.Polyamines as constituents of the outer membranes of Escherichia coli and Salmonella typhimurium. J Bacteriol 1991;173: 3695–3699.
  • Bacon DJ, Szymanski CM, Burr DH, Silver RP, Alm RA, Guerry P.A phase-variable capsule is involved in virulence of Campylobacter jejuni 81-176. Mol Microbiol 2001;40: 769–777.
  • Jerome JP, Bell JA, Plovanich-Jones AE, Barrick JE, Brown CT, Mansfield LS.Standing genetic variation in contingency loci drives the rapid adaptation of Campylobacter jejuni to a novel host. Plos One 2011;6: e16399.
  • Alemka A, Nothaft H, Zheng J, Szymanski CM.N-glycosylation of Campylobacter jejuni surface proteins promotes bacterial fitness. Infect Immun 2013;81: 1674–1682.
  • Guerry P, Szymanski CM, Linton D et al.Phase variation of Campylobacter jejuni 81-176 lipooligosaccharide affects ganglioside mimicry and invasiveness in vitro. Infect Immun 2002;70: 787–793.
  • O Croinin T, Backert S.Host epithelial cell invasion by Campylobacter jejuni: trigger or zipper mechanism? Front Cell Infect Microbiol 2012;2: 25.
  • Young KT, Davis LM, Dirita VJ.Campylobacter jejuni: molecular biology and pathogenesis. Nat Rev Microbiol 2007;5: 665–679.
  • Bachtiar BM, Coloe PJ, Fry BN.Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions. FEMS Immunol Med Microbiol 2007;49: 149–154.
  • Guerry P, Poly F, Riddle M, Maue AC, Chen YH, Monteiro MA.Campylobacter polysaccharide capsules: virulence and vaccines. Front Cell Infect Microbiol 2012;2:7.
  • Rashid MH, Kornberg A.Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa. Proc Natl Acad Sci USA 2000;97: 4885–4890.
  • Pei Z, Blaser MJ.PEB1, the major cell-binding factor of Campylobacter jejuni, is a homolog of the binding component in gram-negative nutrient transport systems. J Biol Chem 1993;268: 18717–18725.
  • Jin S, Joe A, Lynett J, Hani EK, Sherman P, Chan VL.JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells. Mol Microbiol 2001;39: 1225–1236.
  • Chandrashekhar K, Gangaiah D, Pina-Mimbela R, Kassem II, Jeon BH, Rajashekara G.Transducer like proteins of Campylobacter jejuni 81-176: role in chemotaxis and colonization of the chicken gastrointestinal tract. Front Cell Infect Microbiol 2015;5:46.
  • Pesci EC, Cottle DL, Pickett CL.Genetic, enzymatic, and pathogenic studies of the iron superoxide dismutase of Campylobacter jejuni. Infect Immun 1994;62: 2687–2694.
  • Ehrt S, Schnappinger D.Mycobacterium tuberculosis virulence: lipids inside and out. Nat Med 2007;13: 284–285.
  • Louwen R, Heikema A, van Belkum A et al.The sialylated lipooligosaccharide outer core in Campylobacter jejuni is an important determinant for epithelial cell invasion. Infect Immun 2008;76: 4431–4438.
  • Kanistanon D, Powell DA, Hajjar AM et al.Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infect Immun 2012;80: 943–951.
  • Elmi A, Watson E, Sandu P et al.Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. Infect Immun 2012;80: 4089–4098.
  • Samuelson DR, Eucker TP, Bell JA, Dybas L, Mansfield LS, Konkel ME.The Campylobacter jejuni CiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease. Cell Commun Signal 2013;11: 79.

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