References
- DienstagJLHepatitis B virus infectionN. Engl. J. Med.2008359 1486 150010.1056/NEJMra0801644
- TrepoCChanHLLokAHepatitis B virus infectionLancet20143842053206310.1016/S0140-6736(14)60220-8
- LiangTJPresent and future therapies of hepatitis B: from discovery to cureHepatology2015621893190810.1002/hep.280254681668
- KockJEfficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virusJ. Virol.2001755084508910.1128/JVI.75.11.5084-5089.2001114913
- GriponPHepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxideJ. Virol.19886241364143253845
- GallePRIn vitro experimental infection of primary human hepatocytes with hepatitis B virusGastroenterology199410666467310.1016/0016-5085(94)90700-5
- WashburnMLA humanized mouse model to study hepatitis C virus infection, immune response, and liver diseaseGastroenterology20111401334134410.1053/j.gastro.2011.01.0013066273
- BissigKDHuman liver chimeric mice provide a model for hepatitis B and C virus infection and treatmentJ. Clin. Invest.201012092493010.1172/JCI400942827952
- DandriMRepopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virusHepatology20013398198810.1053/jhep.2001.23314
- KosakaKA novel TK-NOG based humanized mouse model for the study of HBV and HCV infectionsBiochem. Biophys. Res. Commun.201344123023510.1016/j.bbrc.2013.10.040
- TsugeMInfection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virusHepatology2005421046105410.1002/hep.20892
- CarpentierAEngrafted human stem cell-derived hepatocytes establish an infectious HCV murine modelJ. Clin. Invest.20141244953496410.1172/JCI754564347235
- BilityMTHepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophagesPLoS. Pathog.201410e100403210.1371/journal.ppat.10040323961374
- SugiyamaMDirect cytopathic effects of particular hepatitis B virus genotypes in severe combined immunodeficiency transgenic with urokinase-type plasminogen activator mouse with human hepatocytesGastroenterology200913665262 e310.1053/j.gastro.2008.10.048
- Mason, W. S. Animal models and the molecular biology of hepadnavirus infection. Cold Spring Harb. Perspect. Med. 5, a021352 (2015).
- de JongYPRiceCMPlossANew horizons for studying human hepatotropic infectionsJ. Clin. Invest.201012065065310.1172/JCI423382827969
- AllweissLDandriMExperimental in vitro and in vivo models for the study of human hepatitis B virus infectionJ. Hepatol.201664S17S3110.1016/j.jhep.2016.02.012
- ThomasELiangTJExperimental models of hepatitis B and C - new insights and progressNat. Rev. Gastroenterol. Hepatol.20161336237410.1038/nrgastro.2016.375578419
- DandriMPetersenJChimeric mouse model of hepatitis B virus infectionJ. Hepatol.20125649349510.1016/j.jhep.2011.05.037
- GriponPInfection of a human hepatoma cell line by hepatitis B virusProc. Natl. Acad. Sci. USA200299156551566010.1073/pnas.232137699
- CerecVTransdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitorHepatology20074595796710.1002/hep.21536
- HantzOPersistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cellsJ. Gen. Virol.20099012713510.1099/vir.0.004861-0
- PhillipsSAlisporivir inhibition of hepatocyte cyclophilins reduces HBV replication and hepatitis B surface antigen productionGastroenterology201514840314 e710.1053/j.gastro.2014.10.004
- GriponPCannieIUrbanSEfficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface proteinJ. Virol.2005791613162210.1128/JVI.79.3.1613-1622.2005544121
- NunnADThe histone deacetylase inhibiting drug Entinostat induces lipid accumulation in differentiated HepaRG cellsSci. Rep.2016610.1038/srep280254913258
- HiguchiYThe human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG miceXenobiotica20144414615310.3109/00498254.2013.836257
- XiaYHuman stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactionsJ. Hepatol.20176649450310.1016/j.jhep.2016.10.009
- ShanJIdentification of small molecules for human hepatocyte expansion and iPS differentiationNat. Chem. Biol.2013951452010.1038/nchembio.12703720805
- FanFPharmacological targeting of kinases MST1 and MST2 augments tissue repair and regenerationSci. Transl. Med20168352ra10810.1126/scitranslmed.aaf2304
- ShiXLImproved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytesCell Res.20162620621610.1038/cr.2016.64746613
- YuanLA chimeric humanized mouse model by engrafting the human induced pluripotent stem cell-derived hepatocyte-like cell for the chronic hepatitis B virus infectionFront. Microbiol.2018990810.3389/fmicb.2018.009085952038
- DurantelDZoulimFNew antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virusJ. Hepatol.201664S117S13110.1016/j.jhep.2016.02.016
- BlankAFirst-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex BJ. Hepatol.20166548348910.1016/j.jhep.2016.04.013
- WatashiKCyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)Hepatology2014591726173710.1002/hep.269824265264
- VolzTThe entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virusJ. Hepatol.20135886186710.1016/j.jhep.2012.12.008
- KanekoMA novel tricyclic polyketide, vanitaracin A, specifically inhibits the entry of hepatitis B and D viruses by targeting sodium taurocholate cotransporting polypeptideJ. Virol.201589119451195310.1128/JVI.01855-154645323
- KoCThe FDA-approved drug irbesartan inhibits HBV-infection in HepG2 cells stably expressing sodium taurocholate co-transporting polypeptideAntivir. Ther.20152083584210.3851/IMP2965
- NiYUrbanSStem cell-derived hepatocytes: a promising novel tool to study hepatitis B virus infectionJ. Hepatol.20176647347510.1016/j.jhep.2016.11.027
- SellsMAZelentAZShvartsmanMAcsGReplicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virionsJ. Virol.19886228362844253719
- PaganelliMDifferentiated umbilical cord matrix stem cells as a new in vitro model to study early events during hepatitis B virus infectionHepatology201357596910.1002/hep.26006
- LuciforaJControl of hepatitis B virus replication by innate response of HepaRG cellsHepatology201051637210.1002/hep.23230
- SchulzeAGriponPUrbanSHepatitis B virus infection initiates with a large surface protein-dependent binding to heparan sulfate proteoglycansHepatology2007461759176810.1002/hep.21896
- LuangsaySExpression and functionality of Toll- and RIG-like receptors in HepaRG cellsJ. Hepatol.2015631077108510.1016/j.jhep.2015.06.022
- LuangsaySEarly inhibition of hepatocyte innate responses by hepatitis B virusJ. Hepatol.2015631314132210.1016/j.jhep.2015.07.014
- KudoTEndoYTaguchiRYatsuMItoKMetronidazole reduces the expression of cytochrome P450 enzymes in HepaRG cells and cryopreserved human hepatocytesXenobiotica20154541341910.3109/00498254.2014.990948
- KanekoAIn vitro model for the prediction of clinical CYP3A4 induction using HepaRG cellsXenobiotica20093980381010.3109/00498250903184018
- ZhangTYProlonged suppression of HBV in mice by a novel antibody that targets a unique epitope on hepatitis B surface antigenGut20166565867110.1136/gutjnl-2014-308964
- AzumaHRobust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- miceNat. Biotechnol.20072590391010.1038/nbt13263404624
- WuYSleeping Beauty transposon-based system for rapid generation of HBV-replicating stable cell linesJ. Virol. Methods20162349610010.1016/j.jviromet.2016.04.010
- HuangCHInfluence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donorsJ. Hepatol.20125772072910.1016/j.jhep.2012.05.009
- WuHLRNA interference-mediated control of hepatitis B virus and emergence of resistant mutantGastroenterology200512870871610.1053/j.gastro.2004.12.007
- HirtBSelective extraction of polyoma DNA from infected mouse cell culturesJ. Mol. Biol.19672636536910.1016/0022-2836(67)90307-5
- GuoHCharacterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formationJ. Virol.200781124721248410.1128/JVI.01123-072169032