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Original Articles

Rv2346c enhances mycobacterial survival within macrophages by inhibiting TNF-α and IL-6 production via the p38/miRNA/NF-κB pathway

, , , , , , , , & show all
Pages 1-16 | Received 16 Apr 2018, Accepted 20 Aug 2018, Published online: 13 Sep 2018

References

  • O’GarraAThe immune response in tuberculosisAnnu. Rev. Immunol.201331 475 52710.1146/annurev-immunol-032712-095939
  • MatsuoKYasutomiYMycobacterium bovis Bacille Calmette-Guerin as a vaccine vector for global infectious disease controlTuberc. Res. Treat.201120115745913335490
  • NieuwenhuizenNEThe recombinant Bacille Calmette-Guerin vaccine VPM1002: ready for clinical efficacy testingFront. Immunol.20178114710.3389/fimmu.2017.01147
  • XuGWangJGaoGFLiuCHInsights into battles between Mycobacterium tuberculosis and macrophagesProtein Cell2014572873610.1007/s13238-014-0077-5
  • UnderhillDMOzinskyASmithKDAderemAToll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophagesProc. Natl Acad. Sci. USA199996144591446310.1073/pnas.96.25.14459
  • FlynnJLChanJImmunology of tuberculosisAnnu. Rev. Immunol.2001199312910.1146/annurev.immunol.19.1.93
  • KunduMA TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosisNat. Immunol.20091091892610.1038/ni.1754
  • MartinezANMehraSKaushalDRole of interleukin 6 in innate immunity to Mycobacterium tuberculosis infectionJ. Infect. Dis.20132071253126110.1093/infdis/jit037
  • HarapanHThe roles of microRNAs on tuberculosis infection: meaning or myth?Tuberc. (Edinb.)20139359660510.1016/j.tube.2013.08.004
  • SamtenBWangXBarnesPFMycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responsesTuberculosis (Edinb.)200989Suppl 1S74S7610.1016/S1472-9792(09)70017-4
  • ManzanilloPSShilohMUPortnoyDACoxJSMycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophagesCell Host Microbe20121146948010.1016/j.chom.2012.03.007
  • SimeoneRPhagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell deathPLoS Pathog.20128e100250710.1371/journal.ppat.1002507
  • MahairasGGSaboPJHickeyMJSinghDCStoverCKMolecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovisJ. Bacteriol.19961781274128210.1128/jb.178.5.1274-1282.1996
  • MohantySMycobacterium tuberculosis EsxO (Rv2346c) promotes bacillary survival by inducing oxidative stress mediated genomic instability in macrophagesTuberculosis (Edinb.)201696445710.1016/j.tube.2015.11.006
  • HossainMMNorazmiMNPattern recognition receptors and cytokines in Mycobacterium tuberculosis infection--the double-edged sword?Biomed. Res. Int.2013201317917410.1155/2013/179174
  • MatucciAMaggiEVultaggioACellular and humoral immune responses during tuberculosis infection: useful knowledge in the era of biological agentsJ. Rheumatol. Suppl.201491172310.3899/jrheum.140098
  • ZhaoWMycobacterium bovis ornithine carbamoyltransferase, MB1684, induces proinflammatory cytokine gene expression by activating NF-kappaB in macrophagesDNA Cell Biol.20143331131910.1089/dna.2013.2026
  • GaspariniCFeldmannMNF-kappaB as a target for modulating inflammatory responsesCurr. Pharm. Des.2012185735574510.2174/138161212803530763
  • ChoSSLDual-specificity phosphatase 12 targets p38 MAP kinase to regulate macrophage response to intracellular bacterial infectionFront. Immunol.20178125910.3389/fimmu.2017.01259
  • JungblutPRComparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogensMol. Microbiol1999331103111710.1046/j.1365-2958.1999.01549.x
  • AmaralEPLasunskaiaEBD’Imperio-LimaMRInnate immunity in tuberculosis: how the sensing of mycobacteria and tissue damage modulates macrophage deathMicrobes Infect.201618112010.1016/j.micinf.2015.09.005
  • SiaJKGeorgievaMRengarajanJInnate immune defenses in human tuberculosis: an overview of the interactions between Mycobacterium tuberculosis and innate immune cellsJ. Immunol. Res2015201574754310.1155/2015/747543
  • LinPLPlessnerHLVoitenokNNFlynnJLTumor necrosis factor and tuberculosisJ. Investig. Dermatol. Symp. Proc.200712222510.1038/sj.jidsymp.5650027
  • FlynnJLChanJImmune evasion by Mycobacterium tuberculosis: living with the enemyCurr. Opin. Immunol.20031545045510.1016/S0952-7915(03)00075-X
  • TorradoECooperAMCytokines in the balance of protection and pathology during mycobacterial infectionsAdv. Exp. Med. Biol.201378312114010.1007/978-1-4614-6111-1_7
  • LadelCHLethal tuberculosis in interleukin-6-deficient mutant miceInfect. Immun.19976548434849175695
  • ReedMBA glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune responseNature2004431848710.1038/nature02837
  • Fallahi-SichaniMKirschnerDELindermanJJNF-kappaB signaling dynamics play a key role in infection control in tuberculosisFront Physiol.2012317010.3389/fphys.2012.00170
  • LiHLiQYuZZhouMXieJMycobacterium tuberculosis PE13 (Rv1195) manipulates the host cell fate via p38-ERK-NF-kappaB axis and apoptosisApoptosis20162179580810.1007/s10495-016-1249-y
  • TsitsiouELindsayMAMicroRNAs and the immune responseCurr. Opin. Pharmacol.2009951452010.1016/j.coph.2009.05.003
  • BrookMPosttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathwaysMol. Cell Biol.2006262408241810.1128/MCB.26.6.2408-2418.2006
  • AbdallaAEDuanXDengWZengJXieJMicroRNAs play big roles in modulating macrophages response toward mycobacteria infectionInfect. Genet. Evol.20164537838210.1016/j.meegid.2016.09.023
  • RajaramMVMycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125bProc. Natl Acad. Sci. USA2011108174081741310.1073/pnas.1112660108
  • SinghYMycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunityJ. Biol. Chem.20132885056506110.1074/jbc.C112.439778
  • KimKHMycobacterial heparin-binding hemagglutinin antigen activates inflammatory responses through PI3-K/Akt, NF-kappaB, and MAPK pathwaysImmune Netw.20111112313310.4110/in.2011.11.2.123
  • WangCHHeat shock protein70 is implicated in modulating NF-kappaB activation in alveolar macrophages of patients with active pulmonary tuberculosisSci. Rep.2017710.1038/s41598-017-01405-z
  • Torres-Huerta, A. et al. Interaction of the CD43 sialomucin with the Mycobacterium tuberculosis Cpn60.2 chaperonin leads to tumor necrosis factor alpha production. Infect. Immun. 85, 10.1128/IAI.00915-16 (2017).
  • LiWMycobacterium tuberculosis Rv3402c enhances mycobacterial survival within macrophages and modulates the host pro-inflammatory cytokines production via NF-kappa B/ERK/p38 signalingPLoS ONE20149e9441810.1371/journal.pone.0094418
  • HuSIL-17 production of neutrophils enhances antibacteria ability but promotes arthritis development during Mycobacterium tuberculosis infectionEBioMedicine201723889910.1016/j.ebiom.2017.08.001
  • IwasakiAMedzhitovRToll-like receptor control of the adaptive immune responsesNat. Immunol.2004598799510.1038/ni1112
  • van den BlinkBp38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivoJ. Immunol.200116658258710.4049/jimmunol.166.1.582