References
- BradyOJRefining the global spatial limits of dengue virus transmission by evidence-based consensusPLoS Negl. Trop. Dis.20126 e176010.1371/journal.pntd.0001760
- MessinaJPGlobal spread of dengue virus types: mapping the 70 year historyTrends Microbiol.201422138 14610.1016/j.tim.2013.12.011
- ThomasStephen J.EndyTimothy P.RothmanAlan L.Flaviviruses: DengueViral Infections of Humans2014Boston, MASpringer US351381
- ScreatonGMongkolsapayaJYacoubSRobertsCNew insights into the immunopathology and control of dengue virus infectionNat. Rev. Immunol.20151574575910.1038/nri3916
- HalsteadSaacuteNimmannityaSCohenSObservations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recoveredYale J. Biol. Med.1970423112591704
- LittauaRKuraneIEnnisFHuman IgG Fc receptor II mediates antibody-dependent enhancement of dengue virus infectionJ. Immunol.199014431833186
- ChambersTJHahnCSGallerRRiceCMFlavivirus genome organization, expression, and replicationAnnu. Rev. Microbiol.19904464968810.1146/annurev.mi.44.100190.003245
- KuhnRJStructure of dengue virus: implications for flavivirus organization, maturation, and fusionCell200210871772510.1016/S0092-8674(02)00660-8
- ZhangYStructures of immature flavivirus particlesEMBO J.2003222604261310.1093/emboj/cdg270
- ZhangWVisualization of membrane protein domains by cryo-electron microscopy of dengue virusNat. Struct. Mol. Biol.20031090791210.1038/nsb990
- WinklerGRandolphVBCleavesGRRyanTEStollarVEvidence that the mature form of the flavivirus nonstructural protein NS1 is a dimerVirology198816218719610.1016/0042-6822(88)90408-4
- FlamandMDengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashionJ. Virol.19997361046110112675
- LindenbachBDRiceCMGenetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase functionJ. Virol.19997346114621112502
- WattersonDModhiranNYoungPRThe many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor designAntivir. Res.201613071810.1016/j.antiviral.2016.02.014
- ScaturroPCorteseMChatel-ChaixLFischlWBartenschlagerRDengue virus non-structural protein 1 modulates infectious particle production via interaction with the structural proteinsPLoS Pathog.201511e100527710.1371/journal.ppat.1005277
- MillerSKastnerSKrijnse-LockerJBühlerSBartenschlagerRThe non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated mannerJ. Biol. Chem.20072828873888210.1074/jbc.M609919200
- XieXZouJPuttikhuntCYuanZShiPYTwo distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assemblyJ. Virol.2015891298131310.1128/JVI.02882-14
- FalgoutBPethelMZhangYLaiCBoth nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteinsJ. Virol.19916524672475240601
- UmareddyIChaoASampathAGuFVasudevanSGDengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNAJ. Gen. Virol.2006872605261410.1099/vir.0.81844-0
- IssurMThe flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structureRNA2009152340235010.1261/rna.1609709
- Cruz-OliveiraCReceptors and routes of dengue virus entry into the host cellsFEMS Microbiol. Rev.20153915517010.1093/femsre/fuu004
- GarciaMWehbeMLévêqueNBodetCSkin innate immune response to flaviviral infectionEur. Cytokine Netw.2017284151
- HeinzFXAllisonSLStructures and mechanisms in flavivirus fusionAdv. Virus Res.20005523126910.1016/S0065-3527(00)55005-2
- MackenzieJWrapping things up about virus RNA replicationTraffic2005696797710.1111/j.1600-0854.2005.00339.x
- PolacekCFriebePHarrisEPoly (A)-binding protein binds to the non-polyadenylated 3′ untranslated region of dengue virus and modulates translation efficiencyJ. Gen. Virol.20099068769210.1099/vir.0.007021-0
- WelschSComposition and three-dimensional architecture of the dengue virus replication and assembly sitesCell Host Microbe2009536537510.1016/j.chom.2009.03.007
- MukhopadhyaySKuhnRJRossmannMGA structural perspective of the flavivirus life cycleNat. Rev. Microbiol.20053132210.1038/nrmicro1067
- JunjhonJInfluence of pr-M cleavage on the heterogeneity of extracellular dengue virus particlesJ. Virol.2010848353835810.1128/JVI.00696-10
- DejnirattisaiWCross-reacting antibodies enhance dengue virus infection in humansScience201032874574810.1126/science.1185181
- LooYMGaleMImmune signaling by RIG-I-like receptorsImmunity20113468069210.1016/j.immuni.2011.05.003
- AkiraSTakedaKToll-like receptor signallingNat. Rev. Immunol.2004449951110.1038/nri1391
- NasirudeenARIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infectionPLoS Negl. Trop. Dis.20115e92610.1371/journal.pntd.0000926
- WangJPFlavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognitionJ. Immunol.20061777114712110.4049/jimmunol.177.10.7114
- SethRBSunLEaCKChenZJIdentification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3Cell200512266968210.1016/j.cell.2005.08.012
- BaumAGarcía-SastreAInduction of type I interferon by RNA viruses: cellular receptors and their substratesAmino Acids2010381283129910.1007/s00726-009-0374-0
- Sun, B. et al. Dengue virus activates cGAS through the release of mitochondrial DNA. Sci. Rep. 7, 3594 (2017).
- El-BachaTMitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virusBiochim. Biophys. Acta200717721158116610.1016/j.bbadis.2007.08.003
- AguirreSDengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infectionNat. Microbiol.201721703710.1038/nmicrobiol.2017.37
- WuJCyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNAScience201333982683010.1126/science.1229963
- LaiJenn‐HaungWangMei‐YiHuangChuan‐YuehWuChien‐HsiangHungLi‐FengYangChia‐YingKePo‐YuanLuoShue‐FenLiuShih‐JenHoLing‐JunInfection with the dengue RNA virus activates TLR9 signaling in human dendritic cellsEMBO reports2018198e4618210.15252/embr.201846182
- DiamondMSModulation of dengue virus infection in human cells by alpha, beta, and gamma interferonsJ. Virol.2000744957496610.1128/JVI.74.11.4957-4966.2000
- MorrisonJGarcía-SastreASTAT2 signaling and dengue virus infectionJAK-STAT20143e2771510.4161/jkst.27715
- AvirutnanPComplement-mediated neutralization of dengue virus requires mannose-binding lectinMBio20112e002760021110.1128/mBio.00276-11
- ThielSA second serine protease associated with mannan-binding lectin that activates complementNature199738650610.1038/386506a0
- FujitaTMatsushitaMEndoYThe lectin‐complement pathway—its role in innate immunity and evolutionImmunol. Rev.200419818520210.1111/j.0105-2896.2004.0123.x
- Sánchez-VargasIDengue virus type 2 infections of Aedes aegypti are modulated by the mosquito’s RNA interference pathwayPLoS Pathog.20095e100029910.1371/journal.ppat.1000299
- JeangKTRNAi in the regulation of mammalian viral infectionsBMC Biol.20121010.1186/1741-7007-10-58
- KakumaniPKRole of RNA interference (RNAi) in dengue virus replication and identification of NS4B as an RNAi suppressorJ. Virol.2013878870888310.1128/JVI.02774-12
- Urcuqui-InchimaSilvioCabreraJesúsHaenniAnne-LiseInterplay between dengue virus and Toll-like receptors, RIG-I/MDA5 and microRNAs: Implications for pathogenesisAntiviral Research2017147475710.1016/j.antiviral.2017.09.017
- KumaAThe role of autophagy during the early neonatal starvation periodNature20044321032103610.1038/nature03029
- MizushimaNLevineBCuervoAMKlionskyDJAutophagy fights disease through cellular self-digestionNature20084511069107510.1038/nature06639
- PanyasrivanitMInduced autophagy reduces virus output in dengue infected monocytic cellsVirology2011418748410.1016/j.virol.2011.07.010
- LennemannNJCoyneCBDengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134BAutophagy20171332233210.1080/15548627.2016.1265192
- LeeYRAutophagic machinery activated by dengue virus enhances virus replicationVirology200837424024810.1016/j.virol.2008.02.016
- MateoRInhibition of cellular autophagy deranges dengue virion maturationJ. Virol.2013871312132110.1128/JVI.02177-12
- WuYWAutophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralizationSci. Rep.2016610.1038/srep32243
- ElmoreSApoptosis: a review of programmed cell deathToxicol. Pathol.20073549551610.1080/01926230701320337
- NetsawangJNuclear localization of dengue virus capsid protein is required for DAXX interaction and apoptosisVirus Res.201014727528310.1016/j.virusres.2009.11.012
- CatteauADengue virus M protein contains a proapoptotic sequence referred to as ApoptoMJ. Gen. Virol.2003842781279310.1099/vir.0.19163-0
- ShafeeNAbuBakarSDengue virus type 2 NS3 protease and NS2B-NS3 protease precursor induce apoptosisJ. Gen. Virol.2003842191219510.1099/vir.0.19022-0
- RamanathanMPHost cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathwayVirology2006345567210.1016/j.virol.2005.08.043
- Lin, J.-C. et al. Dengue viral protease interaction with NF-kB inhibitor a/b results in endothelial cell apoptosis and hemorrhage development. 193, 1258–1267 (2014).
- ModhiranNDengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integritySci. Transl. Med.20157304ra142304ra14210.1126/scitranslmed.aaa3863
- AvirutnanPVascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complementJ. Infect. Dis.20061931078108810.1086/500949
- AvirutnanPSecreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate EPLoS Pathog.20073e18310.1371/journal.ppat.0030183
- NascimentoEJAlternative complement pathway deregulation is correlated with dengue severityPLoS ONE20094e678210.1371/journal.pone.0006782
- LimontaDCapóVTorresGPérezABGuzmánMGApoptosis in tissues from fatal dengue shock syndromeJ. Clin. Virol.200740505410.1016/j.jcv.2007.04.024
- CostaVVDengue virus-infected dendritic cells, but not monocytes, activate natural killer cells through a contact-dependent mechanism involving adhesion moleculesmBio20178e00741007175539423
- TownsleyE.O'ConnorG.CosgroveC.WodaM.CoM.ThomasS. J.KalayanaroojS.YoonI.-K.NisalakA.SrikiatkhachornA.GreenS.StephensH. A. F.GostickE.PriceD. A.CarringtonM.AlterG.McVicarD. W.RothmanA. L.MathewA.Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cellsClinical & Experimental Immunology2015183341943010.1111/cei.12722
- Keawvichit, R. et al. Differences in activation and tissue homing markers of natural killer cell subsets during acute dengue infection. Immunology153, 455–465 (2017).
- ChangDCEvasion of early innate immune response by 2′-O-methylation of dengue genomic RNAVirology201649925926610.1016/j.virol.2016.09.022
- ChanYKGackMUA phosphomimetic-based mechanism of dengue virus to antagonize innate immunityNat. Immunol.20161752310.1038/ni.3393
- HeZDengue virus subverts host innate immunity by targeting adaptor protein MAVSJ. Virol.2016907219723010.1128/JVI.00221-16
- DalrympleNACimicaVMackowERDengue virus NS proteins inhibit RIG-I/MAVS signaling by blocking TBK1/IRF3 phosphorylation: dengue virus serotype 1 NS4A is a unique interferon-regulating virulence determinantMBio20156e005530051510.1128/mBio.00553-15
- YuCYDengue virus targets the adaptor protein MITA to subvert host innate immunityPLoS Pathog.20128e100278010.1371/journal.ppat.1002780
- BarbierVLangDValoisSRothmanALMedinCLDengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fissionVirology201750014916010.1016/j.virol.2016.10.022
- Chatel-ChaixLDengue virus perturbs mitochondrial morphodynamics to dampen innate immune responsesCell Host Microbe20162034235610.1016/j.chom.2016.07.008
- Muñoz-JordánJLSánchez-BurgosGGLaurent-RolleMGarcía-SastreAInhibition of interferon signaling by dengue virusProc. Natl. Acad. Sci. USA2003100143331433810.1073/pnas.2335168100
- MorrisonJDengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signalingPLoS Pathog.20139e100326510.1371/journal.ppat.1003265
- CooraySThe pivotal role of phosphatidylinositol 3-kinase–Akt signal transduction in virus survivalJ. Gen. Virol.2004851065107610.1099/vir.0.19771-0
- ChenHHAR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78Antivir. Res.201714215816810.1016/j.antiviral.2017.02.015
- Avirutnan, P. et al. Antagonism of the complement component C4 by flavivirus nonstructural protein NS1. J. Exp. Med. 20092545 (2010).
- ThiemmecaSSecreted NS1 protects dengue virus from mannose-binding lectin-mediated neutralizationJ. Immunol.20161974053406510.4049/jimmunol.1600323
- CondeJNInhibition of the membrane attack complex by dengue virus NS1 through interaction with vitronectin and terminal complement proteinsJ. Virol.2016909570958110.1128/JVI.00912-16
- KurosuTChaichanaPYamateMAnantapreechaSIkutaKSecreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1Biochem. Biophys. Res. Commun.20073621051105610.1016/j.bbrc.2007.08.137
- KakumaniPKDengue NS3, an RNAi suppressor, modulates the human miRNA pathways through its interacting partnerBiochem. J.2015471899910.1042/BJ20150445
- LiJDengue virus utilizes calcium modulating cyclophilin-binding ligand to subvert apoptosisBiochem. Biophys. Res. Commun.201241862262710.1016/j.bbrc.2012.01.050
- KumarRSinghNAbdinMZPatelAHMedigeshiGRDengue virus capsid interacts with DDX3X–a potential mechanism for suppression of antiviral functions in dengue infectionFront. Cell. Infect. Microbiol.2017754210.3389/fcimb.2017.00542
- AguiarMStollenwerkNHalsteadSBThe risks behind Dengvaxia recommendationLancet Infect. Dis.20161688210.1016/S1473-3099(16)30168-2
- Organization, W. H. et al. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control (World Health Organization, Geneva, 2009).
- XieXInhibition of dengue virus by targeting viral NS4B proteinJ. Virol.201185111831119510.1128/JVI.05468-11
- ByrdCMA novel inhibitor of dengue virus replication that targets the capsid proteinAntimicrob. Agents Chemother.201357152510.1128/AAC.01429-12
- PellicciaSInhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activitiesJ. Enzym. Inhib. Med. Chem.2017321091110110.1080/14756366.2017.1355791
- WuHNovel dengue virus NS2B/NS3 protease inhibitorsAntimicrob. Agents Chemother.2015591100110910.1128/AAC.03543-14
- WanSWTherapeutic effects of monoclonal antibody against dengue virus NS1 in a STAT1 knockout mouse model of dengue infectionJ. Immunol.20171992834284410.4049/jimmunol.1601523
- LaiYen-ChungChuangYung-ChunChangChih-PengLinYee-ShinPerngGuey-ChuenWuHan-ChungHsiehShie-LiangYehTrai-MingMinocycline suppresses dengue virus replication by down-regulation of macrophage migration inhibitory factor-induced autophagyAntiviral Research2018155283810.1016/j.antiviral.2018.05.002
- LeeCJLiaoCLLinYLFlavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stage of virus infectionJ. Virol.2005798388839910.1128/JVI.79.13.8388-8399.2005
- Yu, J.-S. et al. Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway. Sci. Rep.7 45171 (2017).
- Aoki-UtsuboCBroad-spectrum antiviral agents: secreted phospholipase A 2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membraneSci. Rep.2017710.1038/s41598-016-0028-x
- HeLHannonGJMicroRNAs: small RNAs with a big role in gene regulationNat. Rev. Genet.2004552210.1038/nrg1379