Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017

Cong ChenMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChina

Zuliang LiuMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChina

Liguo LiuMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChina

Yan XiaoMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChina

Jianmin WangMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChinaCorrespondence[email protected]

Qi JinMOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen BiologyChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijingChina;Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesHangzhouChinaCorrespondence[email protected]

Pages 1-9 | Received 26 Jun 2018, Accepted 08 Oct 2018, Published online: 14 Nov 2018

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https://doi.org/10.1038/s41426-018-0182-2
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References

GaoRHuman infection with a novel avian-origin influenza A (H7N9) virusNew Engl. J. Med2013368 1888 189710.1056/NEJMoa1304459
PubMed Web of Science ®Google Scholar
WHO. Human infection with avian influenza A (H7N9) virus-China. (2017).
Google Scholar
LuHAn analysis of microbiota-targeted therapies in patients with avian influenza virus subtype H7N9 infectionBMC Infect. Dis.20141410.1186/1471-2334-14-359
Web of Science ®Google Scholar
LuHFDisordered oropharyngeal microbial communities in H7N9 patients with or without secondary bacterial lung infectionEmerg. Microbes Infect.2017610.1038/emi.2017.101
Web of Science ®Google Scholar
ZhuHInfectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and PigsScience201334118318610.1126/science.1239844
PubMed Web of Science ®Google Scholar
ChanRWYChanMCWNichollsJMPeirisJSMTropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tractLancet Respir. Med2013153454210.1016/S2213-2600(13)70138-3
PubMed Web of Science ®Google Scholar
KeCHuman Infection with Highly Pathogenic Avian Influenza A(H7N9) Virus, ChinaEmerg. Infect. Dis.2017231332134010.3201/eid2308.170600
PubMed Web of Science ®Google Scholar
ImaiMA Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory DropletsCell Host & Microbe20172261510.1016/j.chom.2017.09.008
PubMed Web of Science ®Google Scholar
ZhangFHuman infections with recently-emerging highly pathogenic H7N9 avian influenza virus in ChinaJ. Infect.201775717510.1016/j.jinf.2017.04.001
PubMed Web of Science ®Google Scholar
HuYAssociation between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistanceLancet2013381227310.1016/S0140-6736(13)61125-3
PubMed Web of Science ®Google Scholar
YenHLResistance to Neuraminidase Inhibitors Conferred by an R292K Mutation in a Human Influenza Virus H7N9 Isolate Can Be Masked by a Mixed R/K Viral PopulationMBio20134161610.1128/mBio.00396-13
Web of Science ®Google Scholar
Henry DunandCJBoth Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer ProtectionCell Host & Microbe20161980081310.1016/j.chom.2016.05.014
PubMed Web of Science ®Google Scholar
JacksonLAEffect of Varying Doses of a Monovalent H7N9 Influenza Vaccine With and Without AS03 and MF59 Adjuvants on Immune Response: A Randomized Clinical TrialJ. Am. Med Assoc.201531423724610.1001/jama.2015.7916
PubMed Web of Science ®Google Scholar
Henry DunandCJPreexisting human antibodies neutralize recently emerged H7N9 influenza strainsJ. Clin. Invest20151251255126810.1172/JCI74374
PubMed Web of Science ®Google Scholar
HuiDSLeeNChanPKSClinical management of pandemic 2009 influenza A(H1N1) infectionChest201013791610.1378/chest.09-2344
PubMed Web of Science ®Google Scholar
HuiDSInfluenza A/H5N1 infection: other treatment options and issuesRespirology200813S2210.1111/j.1440-1843.2008.01250.x
PubMed Web of Science ®Google Scholar
TCLEMKJLJSLHMeta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?Ann. Intern Med200614559910.7326/0003-4819-145-8-200610170-00139
PubMed Web of Science ®Google Scholar
WuYA potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virusNat. Commun.2015610.1038/ncomms8708
Web of Science ®Google Scholar
ThornburgNJH7N9 influenza virus neutralizing antibodies that possess few somatic mutationsJ. Clin. Invest20161261482149410.1172/JCI85317
PubMed Web of Science ®Google Scholar
YuFA Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza HemagglutininCell Host & Microbe20172247110.1016/j.chom.2017.08.011
PubMed Web of Science ®Google Scholar
WangJCharacterization of Two Human Monoclonal Antibodies Neutralizing Influenza A H7N9 VirusesJ. Virol.2015899115911810.1128/JVI.01295-15
PubMed Web of Science ®Google Scholar
ChenZHuman monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virusNat. Commun.2015610.1038/ncomms7714
Web of Science ®Google Scholar
ChenCStructural insight into a human neutralizing antibody against influenza virus H7N9J. Virol.20179218501817
Web of Science ®Google Scholar
HuangJBroad and potent neutralization of HIV-1 by a gp41-specific human antibodyNature201249140641210.1038/nature11544
PubMed Web of Science ®Google Scholar
WalkerLMBroad neutralization coverage of HIV by multiple highly potent antibodiesNature201147746647010.1038/nature10373
PubMed Web of Science ®Google Scholar
StettlerKSpecificity, cross-reactivity, and function of antibodies elicited by Zika virus infectionScience201635382310.1126/science.aaf8505
PubMed Web of Science ®Google Scholar
WangQMolecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virusSci. Transl. Med20168369379
Web of Science ®Google Scholar
WuYNeutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain IIIEmerg. Microbes Infect.2017610.1038/emi.2017.79
Web of Science ®Google Scholar
ChenYA novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike proteinEmerg. Microbes Infect.2017610.1038/emi.2017.18
Web of Science ®Google Scholar
JiangLPotent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoproteinSci. Transl. Med.2014623425910.1126/scitranslmed.3008140
Web of Science ®Google Scholar
YingTExceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodiesJ. Virol.2014887796780510.1128/JVI.00912-14
PubMed Web of Science ®Google Scholar
ChenZheBaoLinlinChenCongZouTingtingXueYingLiFengdiLvQiGuSongzhiGaoXiaopanCuiShengWangJianminQinChuanJinQiHuman Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common MarmosetThe Journal of Infectious Diseases2017215121807181510.1093/infdis/jix209
PubMed Web of Science ®Google Scholar
BornholdtZAIsolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreakScience2016351107810.1126/science.aad5788
PubMed Web of Science ®Google Scholar
CortiDProtective monotherapy against lethal Ebola virus infection by a potently neutralizing antibodyScience2016351133910.1126/science.aad5224
PubMed Web of Science ®Google Scholar
WhittleJRRBroadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutininP Natl. Acad. Sci. USA20111081421610.1073/pnas.1111497108
PubMed Web of Science ®Google Scholar
EkiertDCNeutralization of influenza A viruses by insertion of a single antibody loop into the receptor binding siteNature201248952610.1038/nature11414
PubMed Web of Science ®Google Scholar
RussellCAThe global circulation of seasonal influenza A (H3N2) virusesScience200832034010.1126/science.1154137
PubMed Web of Science ®Google Scholar
HayAJGregoryVDouglasARLinYPThe evolution of human influenza virusesPhilos. Trans.2001356186110.1098/rstb.2001.0999
PubMed Web of Science ®Google Scholar
YoshidaRCross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A virusesPlos Pathog.20095e100035010.1371/journal.ppat.1000350
PubMed Web of Science ®Google Scholar
OhshimaNNaturally occurring antibodies in humans can neutralize a variety of influenza virus strains, including H3, H1, H2, and H5J. Virol.2011851104810.1128/JVI.05397-11
PubMed Web of Science ®Google Scholar
XuRStructural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virusScience201032835736010.1126/science.1186430
PubMed Web of Science ®Google Scholar
HongMAntibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding SiteJ. Virol.201387124711248010.1128/JVI.01388-13
PubMed Web of Science ®Google Scholar
Ning, T. et al. Antigenic Drift of H7N9 Viral Hemagglutinin. J Infect Dis, (2018).
Google Scholar
HattaMGaoPHalfmannPKawaokaYMolecular basis for high virulence of Hong Kong H5N1 influenza A virusesScience20012931840184210.1126/science.1062882
PubMed Web of Science ®Google Scholar
SongWThe K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replicationNat. Commun.2014510.1038/ncomms6509
Web of Science ®Google Scholar
Yen, H. L. et al. Resistance to neuraminidase inhibitors conferred by an R292K mutation in a human influenza virus H7N9 isolate can be masked by a mixed R/K viral population. MBio4, (2013).
Google Scholar
Kwon, H. I. et al. Evaluation of the Immune Responses to and Cross-Protective Efficacy of Eurasian H7 Avian Influenza Viruses. J Virol91, (2017).
Google Scholar
NakamuraKDevelopment of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strainVaccine20163432833310.1016/j.vaccine.2015.11.050
PubMed Web of Science ®Google Scholar

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