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Australian and New Zealand Journal of Psychiatry Volume 34, 2000 - Issue 1
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Original Article

How long does it take for antidepressant therapies to act?

Gordon Parker School of Psychiatry, University of New South Wales, Psychiatry Unit, Prince of Wales Hospital, Randwick, New South Wales, 2031, Australia
(Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) (Psychiatrist) (Psychiatrist) (Professor) (Associate Professor) (Liaison Psychiatrist) (Research Assistant) (Professor of Psychiatry) ,
Kay Roy School of Psychiatry, University of New South Wales, Psychiatry Unit, Prince of Wales Hospital, Randwick, New South Wales, 2031, Australia
,
David B. Menkes Dunedin Hospital, Dunedin, New Zealand
,
John Snowdon Department of Psychological Medicine, University of Sydney, Sydney, Australia
,
Philip Boyce Department of Psychological Medicine, University of Sydney, Sydney, Australia
,
David Grounds Melbourne Clinic, Melbourne, Australia
,
Bernard Hughson Canberra Hospital, Canberra, Australia
&
Catherine Stringer , North Hobart, Australia
 show all
Pages 65-70 | Received 28 May 1999, Accepted 18 Aug 1999, Published online: 20 Nov 2010

References

  • Gershon S. Antidepressants: can we determine how quickly they work?. Psychopharmacology Bulletin 1995; 31: 21–22
  • Kuhn R. Uber die behandlung depressiver zustande mit einem Iminopdibenzylderivat. Schweizerische Medizinische Wochenschrift 1957; 87: 1135–1140
  • Stassen HH, Delini‐Stula A, Angst J. Time course of improvement under antidepressant treatment: a survival‐analytical approach. European Neuropsychopharmacology 1993; 3: 127–135
  • Parker G. On brightening up: triggers and trajectories to recovery from depression [editorial]. British Journal of Psychiatry 1996; 168: 263–264
  • Parker G. Mindset revisited. Recovery from depression: triggers and time patterns. Australian and New Zealand Journal of Psychiatry 1996; 30: 442–444
  • Parker G. On lightening up. Improvement trajectories in recovery from depression. Advances in Psychiatric Treatment 1996; 2: 186–193
  • Rodger CR, Scott AI, Whalley LJ. Is there a delay in the onset of the antidepressant effect of electroconvulsive theraphy?. British Journal of Psychiatry, 164: 106–109
  • Scott AIF, Whalley LJ. The onset and rate of the anti‐depressant effective of electroconvulsive therapy. A neglected topic of research. British Journal of Psychiatry 1993; 162: 725–732
  • Parker G, Tennant C, Blignault I. Predicting improvements in patients with non‐endogenous depression. British Journal of Psychiatry 1985; 146: 132–139
  • Parker G, Blignault I. Psychosocial predictors of outcome in subjects with untreated depressive disorder. Journal of Affective Disorders 1985; 8: 73–81
  • Quitkin FM, Stewart JW, McGrath PJ, et al. Further evidence that a placebo response to antidepressants can be identified. American Journal of Psychiatry 1993; 150: 566–570
  • Quitkin FM, McGrath PJ, Stewart JW, et al. Chronological milestones to guide drug change. Archives of General Psychiatry 1996; 53: 785–792
  • Parker G, Roy K, Hadzi‐Pavlovic D, et al. Sub‐typing depression by clinical features: The Australasian data base. Acta Psychiatrica Scandinavica 1999, 2000 (in press)
  • Hamilton M. Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychology 1967; 6: 278–296
  • Parker G, Roussos J, Hadzi‐Pavlovic D, Wilhelm K, Mitchell P, Austin M‐P. Plumbing the depths: some problems in quantifying depression severity. Journal of Affective Disorders 1997; 42: 49–58
  • Priebe S, Gruyters T. The importance of the first three days: predictors of treatment outcome in depressed in‐patients. British Journal of Clinical Psychology 1995; 34: 229–236

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