39
Views
1
CrossRef citations to date
0
Altmetric
Article

Learning from multi-level behaviours in agent-based simulations: a Systems Biology application

&
Pages 196-203 | Received 12 Mar 2009, Accepted 03 Nov 2009, Published online: 19 Dec 2017

References

  • AndreuPCrypt-restricted proliferation and commitment to the paneth cell lineage following APC loss in the mouse intestineDevelopment20051321443145110.1242/dev.01700
  • AokiMTaketoMAdenomatous polyposis coli (apc): A multi-functional tumor suppressor geneJ Cell Sci20071203327333510.1242/jcs.03485
  • BedauMADownward causation and the autonomy of weak emergencePrincipia20033550
  • BomanBMColonic crypt changes during adenoma development in familial adenomatous polypsisAm J Pathol200416551489149810.1016/S0002-9440(10)63407-4
  • BonabeauEDessallesJLDetection and emergenceIntellectica19972258594
  • BoschettiFGrayREmergence and computabilityEmergence: Complexity and Organisation20079120130
  • Chen CC, Nagl SB and Clack CD (2007). Specifying, detecting and analysing emergent behaviours in multi-level agent-based simulations. In: Wainer, G (ed.) Proceedings of the Summer Simulation Conference, Agent-directed simulation SCS.
  • CrutchfieldJPThe calculi of emergence: Computation, dynamics, and inductionPhysica D199475115410.1016/0167-2789(94)90273-9
  • DeguetJDemazeauYMagninLElements about the emergence issue—A survey of emergence definitionsComPlexUs20063243110.1159/000094185
  • FoddeRA targeted chain-termination mutation in the mouse apc gene results in multiple intestinal tumorsProc Natl Acad Sci USA1994918969897310.1073/pnas.91.19.8969
  • GeladiPKowlaskiBRPartial least-squares regression: A tutorialAnal Chim Acta198518511710.1016/0003-2670(86)80028-9
  • GilesRHvanEsJHCleversHCaught up in a wnt storm: Wnt signaling in cancerBiochim biophys acta200316531124
  • GunjiY-PKamiuraMObservational heterarchy enhancing active couplingPhysica D20041981–27410510.1016/j.physd.2004.08.021
  • GunjiY-PSasaiKWakisakaSAbstract heterarchy: Time/state-scale re-entrant formBiosystems2008911133310.1016/j.biosystems.2007.06.005
  • HollandJEmergence—From Chaos to Order2000
  • IlyasMWnt signalling and the mechanistic basis of tumour developmentJ Pathol20052052130–14410.1002/path.1692
  • KrobathKLack of adenomatous polposis coli protein correlates with a decrease in cell migration and overall changes in microtuble stabilityMol Biol Cell200718391091810.1091/mbc.E06-03-0179
  • KubikAToward a formalization of emergenceArtif Life20039416610.1162/106454603321489518
  • LamprechtSALipkinMMigrating colonic crypt epithelial cells: Primary targets for transformationCarcinogenesis200223111777178010.1093/carcin/23.11.1777
  • MorrisonSJKimbleJAsymmetric and symmetric stem-cell divisions in development and cancerNature200644170971068107410.1038/nature04956
  • OshimaMLoss of apc heterozygosity and abnormal tissue binding in nascent intestinal polyps in mice carrying a truncated apc geneProc Natl Acad Sci USA1995924482448610.1073/pnas.92.10.4482
  • PearlJCausality: Models, Reasoning and Inference2000
  • PearsonKOn lines and planes of closest fit to systems of points in spacePhilos Mag19012655957210.1080/14786440109462720
  • RasmussenSAnsatz for dynamical hierarchiesArtif Life2001732935310.1162/106454601317296988
  • RyanAEmergence is coupled to scope, not levelNonlinear Sci, Complexity20071326777
  • SansomOJLoss of apc in vivo immediately perturbs wnt signalling, differentiation, and migrationGenes Dev2004181385139010.1101/gad.287404
  • WilliamsonJCausality2007

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.