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Current Eye Research Volume 16, 1997 - Issue 9
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Research Article

SHORT COMMUNICATION Detection of substance P in human tears by laser desorption mass spectrometry and immunoassay

Ray J. Varnell LSU Eye Center, Louisiana State University Medical Center, School of Medicine, New Orleans, LA, USA
,
Jiong Yan Freeman LSU Eye Center, Louisiana State University Medical Center, School of Medicine, New Orleans, LA, USA
,
Dmitri Maitchouk LSU Eye Center, Louisiana State University Medical Center, School of Medicine, New Orleans, LA, USA
,
Roger W. Beuerman LSU Eye Center, Louisiana State University Medical Center, School of Medicine, New Orleans, LA, USA
&
Bryan M. Gebhardt LSU Eye Center, Louisiana State University Medical Center, School of Medicine, New Orleans, LA, USA
Pages 960-963 | Published online: 02 Jul 2009

References

  • Rudich, L. and Butcher, F. R. (1976) Effects of substance P and eledoisin on K efflux, amylase release and cyclic nucleotide levels in slices of rat parotid gland. Biochim. Biophys. Acta, 444, 704–711.
  • Hökfelt, T., Johansson, O., Ljungdahl, A., Lundberg, J. M. and Schultzberg, M. (1980) Peptidergic neurones. Nature, 284, 515–521.
  • Butler, J. M., Powell, D. and Unger, W. G. (1980) Sub-stance P levels in normal and sensorially denervated rabbit eyes. Exp. Eye Res. 30, 311–313.
  • Butler, J. M., Ruskell, G. L., Cole, D. F., Unger, W. G., Zhang, S. Q., Blank, M. A., McGregor, G. P. and Bloom, S. R. (1984) Effect of VIIth (facial) nerve degeneration on vasoactive intestinal polypeptide and substance P levels in ocular and orbital tissues of the rabbit. Exp. Eye Res. 39, 523–532.
  • Unger, W. G., Butler, J. M., Cole, D. F., Bloom, S. R. and McGregor, G. P. (1981) Substance P. vasoactive intestinal polypeptide (VIP) and somatostatin levels in ocular tissue of normal and sensorially denervated rabbit eyes. (Letter). Exp. Eye Res. 32, 797–801.
  • Rozsa, A. and Beuerman, R. W. (1982) Density and orga-nization of free nerve endings of rabbit corneal epithelium. Pain, 14, 105–120.
  • Bill, A., Stjernschantz, J., Mandahl, A., Brodin, E. and Nilsson, G. (1979) Substance P: release on trigeminal nerve stimulation, effects in the eye. Acta PhysioL Scand. 106, 371–373.
  • Matsumoto, Y., Tanabe, T., Ueda, S. and Kawata, M. (1992) Immunohistochemical and enzymehistochemical studies of peptidergic, aminergic and cholinergic innerva-tion of the lacrimal gland of the monkey (Macaca fus-cata). .1 Auton. Nerv. SysL 37,207–214.
  • Nikkinen, A., Lehtosalo, J. I., Uusitalo, H., Palkama, A. and Panula, P. (1984) The lacrimal glands of the rat and the guinea pig are innervated by nerve fibers containing immunoreactivities for substance P and vasoactive intesti-nal polypeptide. Histochemistry, 81,23–27.
  • Williams, R. M., Singh, J. and Sharkey, K. A. (1994) Innervation and mast cells of the rat exorbital lacrimal gland: the effects of age. J. Auton. Nerv. SysL 47, 95–108.
  • Reid, T. W., Murphy, C. J., Iwahashi, C. K., Fontes, B. A. and Mannis, M. J. (1993) Stimulation of epithelial cell growth by the neuropeptide substance P. J. Cell. Biochem. 52, 476–485.
  • Reid, T., Nilsson, J., von Euler, A. M. and Dalsgaard, C.-J. (1985) Stimulation of connective tissue cell growth by substance P and substance K. Nature, 315, 61–63.
  • Schultz, K.-D., Furkert, J., O'Conner, A., Böttcher, M., Schmidt, M., Baumgarten, C. R. and Kunkel, G. (1996) Determination of substance P in human nasal lavage fluid. Neuropeptides, 30, 117–124.
  • Hillenkamp, F., Karas, M., Beavis, R. C. and Chait, B. T. (1991) Matrix-assisted laser desorption/ionization mass spectrometry of biopolymers. Anal. Chem. 63, 1193A–1203A.
  • Beavis, R. C., Chaudhary, T. and Chait, B. T. (1992) oc-Cyano-4-hydroxycinnamic acid as a matrix for matrix-assisted laser desorption mass spectrometry. (Letter). Organic Mass Spectrom. 27, 156–158.
  • Maitchouk, D. Y., Varnell, R. J., Beuerman, R. W., Yan, J. (1996) Analyzing proteins in tears from patients with dry eye syndrome, with contact lenses, or undergoing photore-fractive keratectomy (PRK). (Abstract). Invest. Ophthal-mol. Vis. Sci. 37, S18.

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