43
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Effect of topically applied 0.1% dexamethasone on endothelial healing and aqueous composition during the repair process of rabbit corneal alkali wounds

, , , , &
Pages 110-116 | Published online: 02 Jul 2009

References

  • Hughes, W. F. Jr. (1946) Alkali burns of the eye II. Clini-cal and pathologic course. iArch. Ophthalmol.i b36,b 189–214.
  • Brown, S. I., Wasserman, H. E., Dunn, M. W. (1969) Alkali burns of the cornea. iArch. Ophthalmol.i b82,b 91–94.
  • Matsuda, H., Smelser, G. K. (1973) Epithelium and stroma in alkali-burned corneas. iArch. Ophthalmol.i b89,b 396–401.
  • Matsuda, H., Smelser, G. K. (1973) Endothelial cells in alkali-burned corneas. Ultrastructural alterations. iArch. Ophthalmol.i b89,b 402–409.
  • Pfister, R. R. (1984) Chemical corneal burns. iInt. Ophthalmol. Clin.i b24(2),b 157–168.
  • Morgan, S. J. (1987) Chemical burns of the eye: causes and management. iBr. J. Ophthalmol.i b71,b 854–857.
  • Chung, J.-H., Fagerholm, P. (1987) Stromal reaction and repair after corneal alkali wound in the rabbit: a quanti-tative microradiographic study. iExp. Eye Res.i b45,b 227–237.
  • Chung, J.-H., Fagerholm, P. (1987) Endothelial healing in rabbit corneal alkali wounds. iActa Ophthalmol.i b65,b 648–656.
  • Chung, J.-H. (1988) Experimental corneal alkali wound healing. iActa Ophthalmol.i b66(supplb b187),b 1–35.
  • Chung, J.-H., Fagerholm, P., Lindstrom, B. (1987) The behaviour of corneal epithelium following a standard-ized alkali wound. iActa Ophthalmol.i b65,b 529–537.
  • Chung, J.-H., Fagerholm, P., Lindstrom, B. (1988) Dry mass and water content in the corneal epithelium and superficial stoma during healing of corneal alkali wounds. iExp. Eye Res.i b46,b 705–715.
  • Chung, J.-H., Fagerholm, P. (1989) Corneal alkali wound healing in the monkey. iActa Ophthalmol.i b67,b 685–693.
  • Chung, J.-H., Fagerholm, P. (1989) Treatment of rabbit corneal alkali wounds with human epidermal growth fac-tor. iCornea,i b8,b 122–128.
  • Chung, J.-H., Fagerholm, P., Lindstrom, B. (1989) Hy-aluronate in healing of corneal alkali wound in the rab-bit. iExp. Eye Res.i b48,b 569–576.
  • Paterson, C. A., Pfister, R. R., Levinson, R. A. (1975) Aqueous humor pH changes after experimental alkali burns. iAm. J. Ophthalmol.i b79,b 414–419.
  • Gonnering, R., Edelhauser, H. F., Van Horn, D. L., Durant, W. (1979) The pH tolerance of rabbit and human cor-neal endothelium. iInvest. Ophthalmol. Vis. Sci.i b18,b 373–390.
  • Newsome, D. A., Gross, J. (1977) Prevention by medroxy-progesterone of perforation in the alkali-burned rabbit cornea: inhibition of collagenolytic activity. iInvest. Ophthalmol. Vis. Sci.i b16,b 21–31.
  • Donshik, P. C., Berman, M. B., Dohlman, C. H., Gage, J., Rose, J. (1978) Effect of topical corticosteroid on ul-ceration in alkali-burned cornea. iArch. Ophthalmol.i b96,b 2117–2120.
  • Gross, J., Aziskhan, R. G., Biswas, C. (1981) Inhibithion of tumor growth, vascularization, and collagenolysis in the rabbit cornea by medroxyprogesterone. iProc. Natl. Acad. Sci. USA,i b78,b 1176–1180.
  • Boneham, G. C., Collin, H. B. (1995) Steroid inhibition of limbal blood and lymphatic vascular cell growth. iCurr. Eye Res.i b14,b 1–10.
  • Zannoni, V., Lynch, M., Goldstein, S., Sato, P. (1974) A rapid micromethod for the determination of ascorbic acid in plasma and tissues. iBiochem. Medi.i b11,b 41–48
  • Raabo, E., Terkilesen, T. C. (1960) On the enzymatic determination of blood glucose. iScand. J. Lab. Invest.i b22,b 485–488.
  • Singh, G. (1985) Corticosteroid in corneal endothelial wound healing. iAnn. Ophthalmol.i b17,b 238–243.
  • Solomon, A., Solberg, Y., Belkin, M., Landshman, N. (1997) Effect of corticosteroids on healing of the cor-neal endothelium in cats. iGrafe's Arch. Clin. Exp. Ophthalmol.i b235,b 325–329.
  • Chung, J.-H., Kang, Y.-G., Kim, H.-J. (1998) Effect of 0.1% dexamethasone on epithelial healing in experimental corneal alkali wounds: morphological changes during the repair process. iGrafe's Arch. Clin. Exp. Ophthalmol.i b236,b 537–545.
  • Chung, J.-H., Park, Y.-K., Lee, J.-S., Kim, W.-K. (1998) Effect of 0.1% dexamethasone on expression of stromal collagen type I and IV mRNA during the repair process of corneal alkali wounds. iInvest. Ophthalmol. Vis. Sci.i b39(supplb b4),b S755.
  • Yu, R. N., Kurata, T., Kim, M., Arakawa, N. (1991) The behavior of L-ascorbic acid in the healing process of dor-sal wounds in guinea pigs. iJ. Neutri. Sci. Vitaminol.i b37,b 207–211.
  • Vaxman, F., Olender, S., Lambert, A., Nisand, G., Aprahamian, M., Bruch, J. F., Didier, E., Volkmar, P., Grenier, J. F. (1995) Effect of pantothenic acid and ascor-bic acid supplementation on human skin wound healing process. A double-blind, prospective and randomized trial. iEur. Surg. Res.i b27,b 158–166.
  • Rose, R. C., Bode, A. M. (1991) Ocular ascorbate trans-port and metabolism. iCompara. Bioch. & Physiol. A-Compara. Physiol.i b100,b 273–285.
  • Nirankari, V. S., Varma, S. D., Lakhanpal, V., Richards, R. D. (1981) Superoxide radical scanvenging agents in treatment of alkali burns: An experimental study. iArch. Ophthalmol.i b99,b 886–887.
  • Pfister, R. R., Paterson, C. A. (1977) Additional clinical and morphological observation on the favorable effect of ascorbate in experimental ocular alkali burns. iInvest. Ophthalmol. Vis. Sci.i b16,b 478–487.
  • Levinson, R. A., Paterson, C. A., Pfister, R. R. (1976) Ascorbic acid prevents corneal ulceration and perfora-tion following experimental alkali burns. iInvest. Ophthalmol.i b15,b 986–993.
  • Pfister, R. R., Paterson, C. A., Hayes, S. A. (1978) Topical ascorbate decreases the incidence of corneal ulceration after experimental alkali burns. iInvest. Ophthalmol. Vis. Sci.i b17,b 1019–1024.
  • Tajima, S., Tokimitsu, I. (1995) Regulation of BPAG2-(180kDa) gene expression in spontaneously transformed murine keratinocytes: tissue distribution, modulation during cell adhesion, and up-regulation by ascorbic acid. iJ. Biochem.i b118(4),b 734–737.
  • Lacroix, B., Didier, E., Grenier, J. F. (1988) Role of panthothenic and ascorbic acid in wound healing pro-cess: in vitro study on fibroblasts. iInt. J. Vitamin & Nutrition Res.i b58,b 407–413.
  • Yu, B. Y., Higginbotham, E. J., Chang, I. L. (1990) Ascor-bic acid modulates the production of fibronectin andlaminin by cells from an eye tissue-trabecular meshwork. iExp. Cell Res.i b187,b 65–68.
  • Schmidt, R. J., Chung, L. Y., Andrews, A. M., Turner, T. D. (1993) Toxicity of L-ascorbic acid to L929 fibro-blast cultures: relevance to biocompatibility testing of materials for use in wound management. iJ. Biomed. Materials Res.i b27,b 521–530.
  • Bode, A. M., Vanderpool, S. S., Carlson, E. C., Meyer, D. A., Rose, R. C. (1991) Ascorbic acid uptake and me-tabolism by corneal endothelium. iInvest. Ophthalmol. Vis. Sci.i b32,b 2266–2271.
  • Bhargava, A. S., Staben, P. (1980) Effect of corticoster-oids on intraocular pressure, ascorbic acid and sialic acid concentrations in aqueous humor and on mucopolysac-charides biosynthesis in the cornea of rabbit. iArzneimittel Forschungi b30,b 1123–1126.
  • Arad, I., Sidi, A., Shohami, E. (1985) Effect of acute hypoxia on ascorbate content of plasma, cerebral cortex and adrenal gland. iJ Neurochem.i b45,b 766–769

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.