Immunohistochemical localization of MYOC/TIGR protein in the trabecular tissue of normal and glaucomatous eyes

Reference

• Polansky JR. HTM cell culture model for steroid effects on intraocular pressure: Overview. In Liitjen-Drecoll E, ed. Basic Aspects of Glaucoma Research III. Stuttgart: Schattauer; 1993:307–318.
   Google Scholar
• Polansky JR, Fauss DJ, Chen P, Chen H, Latjen-Drecoll E, Johnson D, Kurtz RM, Ma ZD, Bloom E, Nguyen TD. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid res-ponse gene product. Ophthalmologica. 1997;211:126–139.
   Google Scholar
• Stone EM, Fingert JH, Alward WLM, Nguyen TD, Polansky JR, Sunden SLF, Nishimura D, Clark AF, Nystuen A, Nichols BE, Mackey DA, Ritch R, Kalenak JW, Craven ER, Sheffield VC. Identification of a gene that causes primary open angle glaucoma. Science. 1997;275:668–670.
   Google Scholar
• Latjen-Drecoll E, May CA, Polansky JR, Johnson DH, Bloemendal H, Nguyen TD. Localization of the stress proteins alpha B-crystallin and trabecular meshwork inducible glucocorticoid response protein in normal and glaucomatous trabecular meshwork. Invest Ophthalmol Vis Sci. 1998;39:517–525.
   Google Scholar
• Karali A, Russell P, Stefani FH, Tamm ER. Localization of myocilin/trabecular meshwork-inducible glucocorti-coid response protein in the human eye. Invest Ophthal-mol Vis Sci. 2000;41:729–740.
   PubMed Web of Science ®Google Scholar
• Kubota R, Noda S, Wang Y, Minoshima S, Asakawa S, Kudoh J, Mashima Y, Oguchi Y, Shimizu N. A novel myosin-like protein (myocilin) expressed in the con-necting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping. Geno-mics. 1997;41:360–369.
   Google Scholar
• Takahashi H, Noda S, Imamura Y, Nagasawa A, Kubota R, Mashima Y, Kudoh J, Oguchi Y, Shimizu N. Mouse myocilin (Myoc) gene expression in ocular tissues. Bio-chem Biophys Res Commun. 1998;248:104–109.
   PubMedGoogle Scholar
• Taniguchi F, Suzuki Y, Shirato S, Ohta S. Clinical phenotype of a Japanese family with primary open angle glaucoma caused by a Pro370Leu mutation in the MYOC/TIGR gene. Jpn J Ophthalmol. 1999;43:80–84.
   PubMed Web of Science ®Google Scholar
• Nguyen TD, Chen P, Huang WD, Chen H, Johnson D, Polansky JR. Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from gluco-corticoid-induced trabecular meshwork cells. J Biol Chem. 1998;273:6341–6350.
   PubMedGoogle Scholar
• Tawara A, Varner HH, Hollyfield JG. Distribution and characterization of sulfated proteoglycans in the human trabecular tissue. Invest Ophthalmol Vis Sci. 1989;30: 2215–2231.
   PubMed Web of Science ®Google Scholar
• Stamer WD, Roberts BC, Howell DN, Epstein DL. Isolation, culture, and characterization of endothelial cells from Schlemm's canal. Invest Ophthalmol Vis Sci. 1998;39:1804–1812.
   PubMed Web of Science ®Google Scholar
• Nguyen TD, Chen P, Huang WD, Chen H, Johnson D, Polansky JR. Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from gluco-corticoid-induced trabecular meshwork cells. J Biol Chem. 1998;273:6341–6350.
   PubMedGoogle Scholar
• Ueda J, Wentz-Hunter KK, Cheng EL, Fukuchi T, Abe H, Yue BYJT. Ultrastructural localization of myocillin/ TIGR in human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci. 2000;41 (suppl. 4):5502.
   Google Scholar
• Adam MF, Belmouden A, Binisti P, Brezin AP, Valtot F, Bechetoille A, Dascotte JC, Copin B, Gomez L, Chaventre A, Bach JF, Garchon HJ. Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma. Hum Mol Genet. 1997;6:2091–2097.
   PubMed Web of Science ®Google Scholar
• Kee C, Ahn BH. TIGR gene in primary open-angle glaucoma and steroid-induced glaucoma. Korean J Oph-thalmol. 1997;11:75–78.
   Google Scholar
• Stoilova D, Child A, Brice G, Crick RP, Fleck BW, Sarfarazi M. Identification of a new `TIGR' mutation in a family with juvenile-onset primary open angle glau-coma. Ophthalmic Genet. 1997;18:109–118.
   PubMed Web of Science ®Google Scholar
• Suzuki Y, Shirato S, Taniguchi F, Ohara K, Nishimaki K, Ohta S. Mutations in the TIGR gene in familial pri-mary open-angle glaucoma in Japan. Am J Hum Genet. 1997;61:1202–1204.
   PubMed Web of Science ®Google Scholar
• Rozsa FW, Shimizu S, Lichter PR, Johnson AT, Othman MI, Scott K, Downs CA, Nguyen TD, Polansky J, Richards JE. GLC1A mutations point to regions of po-tential functional importance on the TIGR/MYOC pro-tein. Mo/ Vis. 1998;4:20.
   Google Scholar
• Angius A, De Gioia E, Loi A, Fossarello M, Sole G, Orzalesi N, Grignolo F, Cao A, Pirastu M. A novel mu-tation in the GLC1A gene causes juvenile open-angle glaucoma in 4 families from the Italian region of Puglia. Arch Ophthalmol. 1998;116:793–797.
   Google Scholar
• Richards JE, Ritch R, Lichter PR, Rozsa FW, Stringham HM, Caronia RM, Johnson D, Abundo GP, Willcockson J, Downs CA, Thompson DA, Musarella MA, Gupta N, Othman MI, Torrez DM, Herman SB, Wong DJ, Higashi M, Boehnke M. Novel trabecular meshwork in-ducible glucocorticoid response mutation in an eight- generation juvenile-onset primary open-angle glaucoma pedigree. Ophthalmology. 1998;105:1698–1707.
   Google Scholar
• Stoilova D, Child A, Brice G, Desai T, Barsoum-Homsy M, Ozdemir N, Chevrette L, Adam MF, Garchon HJ, Pitts Crick R, Sarfarazi M. Novel TIGR/MYOC muta-tions in families with juvenile onset primary open angle glaucoma. J Med Genet. 1998;35:989–992.
   Google Scholar
• Michels-Rautenstrauss KG, Mardin CY, Budde WM, Liehr T, Polansky J, Nguyen T, Timmerman V, Van Broeckhoven C, Naumann GO, Pfeiffer RA, Rauten-strauss BW. Juvenile open angle glaucoma: fine map-ping of the TIGR gene to 1q24.3-q25.2 and mutation analysis. Hum Genet. 1998;102: 103–106.
   Google Scholar
• Mansergh FC, Kenna PF, Ayuso C, Kiang AS, Hum-phries P, Farrar GJ. Novel mutations in the TIGR gene in early and late onset open angle glaucoma. Hum Mutat. 1998;11:244–251.
   Google Scholar
• Kennan AM, Mansergh FC, Fingert JH, Clark T, Ayuso C, Kenna PF, Humphries P, Farrar GJ. A novel Asp380Ala mutation in the GLC1A/myocilin gene in a family with juvenile onset primary open angle glauco-ma. J Med Genet. 1998;35:957–960.
   Google Scholar
• Yokoyama A, Nao-i N, Date Y, Nakazato M, Chumann H, Chihara E, Sawada A, Matsukura S. Detection of a new TIGR gene mutation in a Japanese family with pri-mary open angle glaucoma. Jpn J Ophthalmol. 1999; 43:85–88.
   PubMed Web of Science ®Google Scholar
• Takahashi H, Noda S, Mashima Y, Kubota R, Ohtake Y, Tanino T, Kudoh J, Minoshima S, Oguchi Y, Shimizu N. The myocilin (MYOC) gene expression in the human trabecular meshwork. Curr Eye Res. 2000;20:81–84.
   Google Scholar
• Hirano K, Kobayashi M, Kobayashi K, Hoshino T, Awaya S. Age-related changes of microfibrils in the cornea and trabecular meshwork of the human eye. Jpn J Ophthalmol. 1991;35:166–174.
   Google Scholar
• Fujisawa N. Dexamethasone effects of protein synthesis on organ-cultured human trabecular meshwork-auto-radiographical, biochemical, and immunohistochemical study. Nippon Ganka Gakkai Zasshi. 1994;98:31–37.
   Google Scholar
• Polansky JR. In vitro correlates of glucocorticoid effects on intraocular pressure. In Krieglstein GK, ed. Glauco-ma Update IV. Berlin: Springer-Verlag; 1991:20–29.
   Google Scholar
• Liitjen-Drecoll E, Rittig M, Rauterberg J, Jander R, Mollenhauer J. Immunomicroscopical study of type VI collagen in the trabecular meshwork of normal and glaucomatous eyes. Exp Eye Res. 1989;48:139–147.
   Google Scholar
• Rittig M, Liitjen-Drecoll E, Rauterberg J, Jander R, Mollenhauer J. Type-VI collagen in the human iris and ciliary body. Cell Tissue Res. 1990;259:305–312.
   Google Scholar
• Tamm E, Jungkunz W, Marsch WC, Lutjen-Drecoll E. Increase in types IV and VI collagen in cherry haeman-giomas. Arch Dermatol Res. 1992;284:275–282.
   Google Scholar
• Dietlein TS, Jacobi PC, Frie C, Paulsson M, Krieglstein GK. Immunohistochemical distribution of type VI col-lagen in normal and glaucomatous human trabecular meshwork. Graefes Arch Clin Exp Ophthalmol. 1998; 236:597–601.
   Google Scholar
• Tawara A, Inomata H. Distribution and characterization of sulfated proteoglycans in the trabecular tissue of goniodysgenetic glaucoma. Am J Ophthalmol. 1994; 117:741–755.
   PubMedGoogle Scholar
• Tawara A, Inomata H, Tsukamoto S. Ciliary body band width as an indicator of goniodysgenesis. Am J Ophthal-mol. 1996;122:790–800.
   Google Scholar
• Maul E, Strozzi L, Mutioz C, Reyes C. The outflow pathway in congenital glaucoma. Am J Ophthalmol. 1980;89:667–675.
   PubMedGoogle Scholar
• Tawara A, Inomata H. Developmental immaturity of the trabecular meshwork in congenital glaucoma. Am J Ophthalmol. 1981;92:508–525.
   Google Scholar
• Tawara A, Inomata H. Developmental immaturity of the trabecular meshwork in juvenile glaucoma. Am J Oph-thalmol. 1984;98:82–97.
   Web of Science ®Google Scholar
• Segawa K. Electron microscopic changes of the trabe-cular tissue in primary open-angle glaucoma. Ann Oph-thalmol. 1979;11:49–54.
   PubMed Web of Science ®Google Scholar
• Rohen JW. Why is intraocular pressure elevated in chronic simple glaucoma? Anatomical considerations. Ophthalmology. 1983;90:758–765.
   PubMed Web of Science ®Google Scholar
• Liitjen-Drecoll E, Shimizu T, Rohrbach M, Rohen JW. Quantitative analysis of 'plaque material' in the inner-and outer wall of Schlemm's canal in normal- and glau-comatous eyes. Exp Eye Res. 1986;42:443–455.
   Google Scholar
• Rohen JW, Liitjen-Drecoll E, Fliigel C, Meyer M, Grierson I. Ultrastructure of the trabecular meshwork in untreated cases of primary open-angle glaucoma (POAG). Exp Eye Res. 1993;56:683–692.
   PubMed Web of Science ®Google Scholar
• Knepper PA, Goossens W, Hvizd M, Palmberg PF. Glycosaminoglycans of the human trabecular meshwork in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 1996;37:1360–1367.
   PubMed Web of Science ®Google Scholar
• Tripathi RC, Li J, Chan WF, Tripathi BJ. Aqueous hu-mor in glaucomatous eyes contains an increased level of TGF-I32. Exp Eye Res. 1994;59:723–727.
   PubMed Web of Science ®Google Scholar
• Fukushima D, Butzow R, Hildebrand A, Ruoslahti E. Localization of transforming growth factor beta binding site in betaglycan. Comparison with small extracellular matrix proteoglycans. J Biol Chem. 1993;268:22710–22715.
   Google Scholar
• Takahashi T, Cho HI, Kublin CL, Cintron C. Keratan sulfate and dermatan sulfate proteoglycans associate with type VI collagen in fetal rabbit cornea. J Histochem Cytochem. 1993 ;41:1447–1457.
   PubMed Web of Science ®Google Scholar
• Kimura S, Kobayashi M, Nakamura M, Hirano K, Awaya S, Hoshino T. Immunoelectron microscopic lo-calization of decorin in aged human corneal and scleral stroma. J Electron Microsc (Tokyo). 1995;44:445–449.
   Google Scholar