A practice pathway for the management of gliomas of the anterior visual pathway: an update and an evidence-based approach

References

• Aarabi B, Long DM, Miller NR. Enlarging optic chiasmal glioma with stable visual acuity. Surg Neurol 1978;10:175–177.
   Google Scholar
• Addy DP, Hudson FP. Diencephalic syndrome of infantile emaciation. Arch Dis Child 1972:47:338–343.
   PubMed Web of Science ®Google Scholar
• Albers GW, Hoyt WF, Forno LS. Treatment response in malignant glioma of adulthood. Neurology 1988;38:1071–1074.
   Google Scholar
• Albert A, Lee BCP, Saint-Louis L, et al. MRI of optic chiasm and optic pathways. Am J Neuroradiol 1986;7: 255–258.
   Google Scholar
• Albert D, Puliafito C. Foundations of Ophthalmic Pathology. New York: Appleton-Century-Crofts, 1979.
   Google Scholar
• Albright AL, Sclabassi RJ, Slamovitz IT, et al. Spasmus nutans associated with optic gliomas in infants. J Pediatr 1984;105:778–780.
   PubMed Web of Science ®Google Scholar
• Alper MG. Management of primary optic nerve meningiomas. J Clin Neuro-ophthalmol 1981;i:10I–117.
   Google Scholar
• Alshail E, Rutka JT, Becker LE, et al.Optic chiasmatic-hypothalamic glioma. Brain Pathol 1997;7:799–806.
   PubMed Web of Science ®Google Scholar
• Alvord EC, Lofton S. Gliomas of the optic nerve or chiasm. J Neurosurg 1988;68:85–98.
   PubMed Web of Science ®Google Scholar
• Anderson DR, Spencer WH. Ultrastructural and histochemical observations of optic nerve gliomas. Arch Ophthalmol 1970;83:324–335.
   PubMedGoogle Scholar
• Antony JH, Ouvrier RA, Wise G. Spasmus nutans: a mistaken identity. Arch Neurol 1980;37:373–375.
   PubMedGoogle Scholar
• Applegate LJ, Pribram FW. Hematoma of optic nerve glioma — a cause for sudden proptosis. J Clin Neuro-ophthalmol 1989;9:15–19.
   PubMedGoogle Scholar
• Banford FN, Jones PM, Pearson D, et al. Residual disabilities in children treated for intracranial space-occupying lesions. Cancer 1976; 37:1149–1151.
   PubMed Web of Science ®Google Scholar
• Barbaro NM, Rosenblum ML, Maitland CG, et al. Malignant optic glioma presenting radiologically as a 'cystic' suprasellar mass: case report and review of the literature. Neurosurgery 1982;11 :787–789.
   PubMed Web of Science ®Google Scholar
• Bataini JP, Delanian S, Ponvert D. Chiasmal gliomas: results of irradiation management in 57 patients and review of literature. Int J Radiat Oncol Biol Phys 1991;21: 615–623.
   Google Scholar
• Beyer RA, Pader P, Sobel DF, et al. Moyamoya pattern of vascular occlusion after radiotherapy for glioma of the optic chiasm. Neurology 1986;36:1173–1178.
   PubMed Web of Science ®Google Scholar
• Bilgic S, Erbengi A, Tinaztepe B. Optic glioma of childhood: clinical, histopathological, and histochemical observations. Br J Ophthalmol 1989:73:832–837.
   Google Scholar
• Bleyer WA, Griffin TW. White matter necrosis, microangiopathy and intellectual abilities in survivors of childhood leukemia: associations with central nervous system irradiation and methotrexate therapy. In: Gilbert A, editor. Radiation Damage to the Nervous System. New York: Raven Press, 1980; 155–174.
   Google Scholar
• Bognanno JR, Edwards MK, Lee TT, et al. Cranial MR imaging in neurofibromatosis. Am J Radiol 1988;151:381–388.
   Google Scholar
• Borit A, Richardson EP. The biological and clinical behaviour of pilocytic astrocytomas of the optic pathways. Brain 1982;105:161–187.
   PubMed Web of Science ®Google Scholar
• Brand WN, Hoover SV. Optic glioma in children. Review of 16 cases given mega voltage radiation therapy. Child's Brain 1979;5:459–466.
   Google Scholar
• Brauner R, Malandry F, Rappaport R. Growth and endocrine disorders in optic glioma. Eur J Pediatr 1990;149: 825–828.
   Google Scholar
• Brooks WH, Parker JC, Young AB, et al. Malignant gliomas of the optic chiasm in adolescents. Clin Pediatr 1976;15:557–561.
   PubMed Web of Science ®Google Scholar
• Brown EW, Riccardi VM, Mawad M, et al. MR imaging of optic pathways in patients with neurofibromatosis. Am J Neuro-radiol 1987;8:1031–1036.
   PubMed Web of Science ®Google Scholar
• Bruggers CS, Friedman HS, Phillips PC, et al. Leptomeningeal disseminations of optic pathways gliomas in three children. Am J Ophthalmol 1991;III:719–723.
   Google Scholar
• Brzowski AE, Bazan C, Mumma JV, et al. Spontaneous regression of optic gliomas in a patient with neurofibromatosis. Neurology 1992;42:679–681.
   PubMed Web of Science ®Google Scholar
• Buchanan TAS, Hoyt WF. Optic nerve glioma and neurovascular glaucoma: a report of a case. Br J Ophthalmol 1982;66:96–98.
   PubMed Web of Science ®Google Scholar
• Burki E. Ueber den primaren Sehnerventumor und seine. Beziehungen zur Recklinghausenchen neurofibromatose. Bibl Ophthalmol 1944;30:1–64.
   Google Scholar
• Burr IM, Slonim AE, Danish RK, et al. Diencephalic syndrome revisited. J Pediatr 1976;88:439–444.
   PubMed Web of Science ®Google Scholar
• Byers WGM. The primary intradural tumors of the optic nerve (Fibromatosis nervi optica). Stud R Victoria Hosp, Montreal 1901;1:3–82.
   Google Scholar
• Bynke H, Kagstrom E, Tjernstrom K. Aspects on treatment of gliomas of the anterior visual pathways. Acta Ophthalmol 1977;55:267–280.
   Google Scholar
• Chang CH, Woods EH. The value of radiation therapy for gliomas of the anterior visual pathway. In: Brockhurst RJ, Borouchoff SA, Hutchinson BT, et al., editors. Controversy in Ophthalmology. Philadelphia: W.B. Saunders Co., 1977; 878–886.
   Google Scholar
• Charles NC, Nelson L, Brookner AR, et al. Pilocytic astrocytoma of the optic nerve with hemorrhage and extreme cystic degeneration. Am J Ophthalmol 1981;92:691–695.
   PubMed Web of Science ®Google Scholar
• Charleux J. Les manifestations palpebrale et orbitares de la neurofibromatose de Recklinghausen.
   Google Scholar
• Choutorian AM, Schwartz IF, Evans RA, et al. Optic gliomas in children. Neurology 1964;14:83–95.
   PubMed Web of Science ®Google Scholar
• Choutorian AM, Housepian EM, Hilal S. Optic gliomas of multicentric origin with favorable response to
   Google Scholar
• Choutorian AM, Carter S. What is the proper management of gliomas of the anterior visual pathway? In:
   Google Scholar
• Christensen E, Ry-Andersen S. Primary tumor of optic nerve and chiasm. Acta Phys Neurol Scand 1952;27:5-16. Neurology 1988;38: 562–566.
   Google Scholar
• Condon JR, Rose FC. Optic nerve glioma. Br J Ophthalmol 1967;51:703-.706.
   Google Scholar
• Crawford MJ, Buckler JMH. Optic Neurol 1983;25:370–373.
   Web of Science ®Google Scholar
• Crowe FW, Schull WF. Diagnostic importance of cafe-au-lait spot in neurofibromatosis. Arch Intern Med 1953;91:758–766.
   Google Scholar
• Dandy WE. Results following transcranial operative attack on orbital 749–755.
   Google Scholar
• Danoff BF, Kramer S, Thomson N. The radiotherapeutic management of optic nerve gliomas in children. Int J Radiat Oncol Biol Phys 1980;6:45–50.
   PubMed Web of Science ®Google Scholar
• Davis FA. Primary tumors of the optic nerve (a phenomenon of von Recklinghausen's disease). A clinical and pathologic study with a report of five cases and a review of the literature. Arch Ophthalmol 1940;23: 735–821.
   Google Scholar
• Davis PC, Hofman JC, Weidanheim KM. Large hypothalamic and optic chiasm gliomas in infants: difficulties in distinction. Am J Neuro-radiol 1984:5:579–585.
   Google Scholar
• Davis PC, Hoffman JC, Pearl GS, et al. CT evaluation of effects of cranial radiation therapy in children. Am J Neuro-radiol 1986;7:639–644.
   Web of Science ®Google Scholar
• de Keizer RJW, de Wolff D, Bots GTA, et al. Optic gliomas with intraocular tumor and seeding in a child with neurofibromatosis. Am J Ophthalmol 1989;108:717–725.
   PubMed Web of Science ®Google Scholar
• Debrun G, Sauvegrain J, Aicardi J, et al. Moya-Moya, a nonspecific radiologic syndrome. Neuroradiology 1975;8:241–244.
   Web of Science ®Google Scholar
• Deliganis AV, Geyer JR, Berger MS. Prognostic significance of type I neurofibromatosis (von Reckling-hausen Disease) in childhood optic glioma. Neurosurgery 1996;38:1114–1118.
   Google Scholar
• Desoretz DE, Blitzer PH, Wang CC, et al. Management of gliomas of the optic nerve and/or chiasm. Cancer 1980;45:1467–1471.
   PubMed Web of Science ®Google Scholar
• DeSousa AL, Kalsbeck JE, Mealey J, et al. Optic chiasmatic glioma in children. Am J Ophthalmol 1979;87: 376–381.
   PubMed Web of Science ®Google Scholar
• DeSousa AL, Kalsbeck JE, Mealey J, et al. Diencephalic syndrome and its relation to opticochiasmatic glioma: review of twelve cases. Neurosurgery 1979;4:207–209.
   PubMed Web of Science ®Google Scholar
• DiMario FJ, Ramsby G, Greenastein R, et al. Neurofibromatosis type I: magnetic resonance imaging findings. J Child Neurol 1993;8:32–39.
   PubMed Web of Science ®Google Scholar
• Donaldson DD. Atlas of External Diseases of the Eye. Anterior Chamber, Iris, and Ciliary Body. St Louis: CF Mosby, 1973; 238.
   Google Scholar
• Dossetor FM, Laudau K, Hoyt WF. Optic disk glioma in neurofibromato-sis type 2. Am J Ophthalmol 1989;108: 602–603.
   Google Scholar
• Dresner E, Montgomery DAD. Primary optic atrophy in Von Recklinghausen's disease (multiple neurofibromatosis). Q J Med 1949;18:93–103.
   PubMedGoogle Scholar
• Dutton JJ. Gliomas of the anterior visual pathway. Surv Ophthalmol 1994;38:427–452.
   PubMed Web of Science ®Google Scholar
• Easley JD, Scharf L, Chou L, et al. Controversy in the management of optic pathway gliomas. Neurofibroma-tosis 1988;1:248–251.
   PubMedGoogle Scholar
• Eggers H, Jakobiec FA, Jones IS. Tumors of the optic nerve. Doc Ophthalmol 1976;41:43–128.
   PubMed Web of Science ®Google Scholar
• Ellsworth C, Alvord MD, Lofton S. Gliomas of the optic nerve or chiasm. J Neurosurg 1988;68:85–98.
   Google Scholar
• Epstein MA, Packer RJ, Rorke LB, et al. Vascular malformation with radiation vasculopathy after treatment of chiasmatic hypothalamic glioma. Cancer 1992;70:887–893.
   PubMed Web of Science ®Google Scholar
• Evens PA, Brihaya M, Buissert T, et al. Gliome malin du chiama chez l'adulte. Bull Soc Belge Ophthalmol 1987;224:59–60.
   PubMedGoogle Scholar
• Flickinger JC, Tones C, Deursch M. Management of low-grade gliomas of the optic nerve and chiasm. Cancer 1988;61:635–642.
   Google Scholar
• Foerster 0, Gagel 0. Ein Fall von song. Gliom des Nervus opticus. Spongioblastoma multiforme ganglioides. Z Gesamte Neurol Psychiatr 1931;146:335–366.
   Google Scholar
• Fog J, Seedorff HH, Vaernet K. Optic glioma. Clinical features and treatment. Acta Ophthalmol 1970;48: 644–653.
   Google Scholar
• Forrest A. Optic glioma. XIX Concilium Ophthalmologicum 1962M:1204–1210.
   Google Scholar
• Fowler FD, Matson DD. Gliomas of the optic pathways in children. J Neurosurg 1957;14:515–528.
   PubMed Web of Science ®Google Scholar
• Frazier BS, Glazer JS. Orbital tissue differentiation with standardized echograhy. Ophthalmology 1983;90:1071–1090.
   PubMed Web of Science ®Google Scholar
• Frazier BS. Standardized echography in the differentiation of orbital lesions. Surg Ophthalmol 1984;29:226–228.
   PubMed Web of Science ®Google Scholar
• Frazier BS. Evaluation of the optic nerve with standardized echography. In: Smith IL, editor. Neuro-oph-thalmology Now New York: Field Rich and Associates, Inc., 1986; 45–66.
   Google Scholar
• Frohman LP, Epstein F, Kupersmith MJ. Atypical visual prognosis with an optic nerve glioma. J Clin Neuro-ophthalmol 1985;5:90–94.
   PubMedGoogle Scholar
• Furuya Y, Uemura K, Ryu H, et al. Optic glioma decreasing in size after irradiation. J Clin Neurol 1985;i:173–175.
   Google Scholar
• Gans MS, Frazier Byrne S, Glaser JS. Standardized A-scan echography in optic nerve disease. Arch Ophthalmol 1987;105:1232–1236.
   PubMedGoogle Scholar
• Garvey M, Packer RJ. An integrated approach to the treatment of chiasmatic hypothalamic gliomas. J Neuro-Oncol 1996;28:167–183.
   PubMed Web of Science ®Google Scholar
• Gibberd FB, Miller TN, Morgan PD. Glioblastoma of the optic chiasm. Br J Ophthalmol 1973;57:788–790.
   PubMed Web of Science ®Google Scholar
• Glaser JS, Hoyt WF, Corbett J. Visual morbidity with chiasmal glioma. Long-term studies of visual fields in untreated and irradiated cases. Arch Ophthalmol 1971;85:3–12.
   Google Scholar
• Glaser JS. Gliomas of the anterior visual pathways in childhood: rationale for conservative management. In: Brockhurst RJ, Borouchoff SA, Hutchinson BT, editors. Controversy in Ophthalmolo-gy. Philadelphia: WB Saunders Co., 1977; 897–909.
   Google Scholar
• Goalwin HA. One thousand optic canals. A clinical anatomic and roentgenologic study. J Am Med Assoc 1927;89:1745–1748.
   Google Scholar
• Gombi R, Hullay J. Optic glioma: diagnosis and treatment of the optic glioma. Acta Neurochir 1979;28:405–408.
   Google Scholar
• Goodman SJ, Rosenbaum AL, Hasso A, et al. Large optic nerve glioma with normal vision. Arch Ophthalmol 1975;93:991–995.
   PubMedGoogle Scholar
• Gould RJ, Hilal SK, Chutorian AM. Efficacy of radiotherapy in optic gliomas. Pediatr Neurol 1987;3:29–32.
   PubMed Web of Science ®Google Scholar
• Grimson BS, Perry DD. Enlargement of the optic disk in childhood optic nerve tumors. Am J Ophthalmol 1984;97:627–631.
   PubMed Web of Science ®Google Scholar
• Haik BG, Saint-Loui L, Bierly J, et al. Magnetic resonance imaging in the evaluation of the optic nerve gliomas. Ophthalmology 1987;94:709–717.
   PubMed Web of Science ®Google Scholar
• Hamilton AM, Garner A, Tripathi RC, et al. Malignant optic glioma. Report of a case with electron microscope study. Br J Ophthalmol 1973;57:253–264.
   Google Scholar
• Harper CG, Stewart-Wynne EG. Malignant optic gliomas in adults. Arch Neurol 1978;35:731-735. Harter DJ, Caderao JB, Leavens ME, et al. Radiotherapy in the management of primary gliomas involving the intracranial optic nerves and chiasm. Radiat Oncol Biol Phys 1978;4: 681–686.
   Google Scholar
• Hendrix LE, Kneeland JB, Houghton VM, et al. MR imaging of optic nerve lesions: value of gadopentate dimeglumine and fat-suppression technique. Am J Neuro-radiol 1990;11:749–754.
   PubMed Web of Science ®Google Scholar
• Hochstrasse H, Boltshuaser E, Valvanis A. Brain tumors in children with von Recklinghausen neurofibromatosis. Neurofibromatosis 1988;1:233–239.
   Google Scholar
• Hoffman HJ, Humphreys RP, Drake JM, et al. Optic pathway/ hypothalamic gliomas: a dilemma in management. Neurosurgery 1993; 19:186–195.
   Web of Science ®Google Scholar
• Holman RE, Grimson BS, Drayer BP, et al. Magnetic resonance imaging of optic gliomas. Am J Ophthalmol 1985;100:596–601.
   PubMed Web of Science ®Google Scholar
• Horwich A, Bloo HJG. Optic gliomas: radiation therapy and prognosis. Int J Radiat Oncol Biol Phys 1985;1i:1067–1079.
   Google Scholar
• Housepian EM. Surgical treatment of unilateral optic nerve gliomas. J Neurosurg 1969;31:604–607.
   PubMed Web of Science ®Google Scholar
• Housepian EM. Management and results of 114 cases of optic glioma. Neurosurgery 1977;i:67–68.
   Google Scholar
• Hovland KR, Ellis PP. Hemorrhagicglaucoma with optic nerve glioma. Arch Ophthalmol 1966;75:8o6-8o9.
   Google Scholar
• Hoyt WF, Baghdassarian SA. Opticgliomas of childhood: natural history and rationale for conservative management. Br J Ophthalmol 1969;53:793–798.
   PubMed Web of Science ®Google Scholar
• Hoyt WF, Meshel LG, Lessel S, et al. Malignant optic glioma of adulthood. Brain 1973;96:121–132.
   PubMed Web of Science ®Google Scholar
• Hoyt WF, Fletcher WA, Imes RK. Chiasmal gliomas. Appearance and long-term changes demonstrated by computerized tomography. Prog Exp Tumor Res 1987;30:1'3-'2i.
   Google Scholar
• Hudson AC. Primary tumors of the optic nerve. R Ophthalmol Hosp 1912;18:317–439.
   Google Scholar
• Hufnagel TJ, Kim JH, Lesser R, et al. Malignant glioma of the chiasm eight years after radiotherapy for prolactinoma. Arch Ophthalmol 1988;106:1701–1705.
   PubMedGoogle Scholar
• Imes RK, Hoyt WF. Childhood chiasmal gliomas: update on the fate of patients in the 1969 San Francisco study. Br J Ophthalmol 1986;70:179–182.
   PubMed Web of Science ®Google Scholar
• Imes RK, Hoyt WF. Childhood chiasmal gliomas. Prog Exp Tumor 1987;30:108–112.
   PubMed Web of Science ®Google Scholar
• Imes RK, Hoyt WF. Magnetic resonance imaging signs of optic nerve gliomas in neurofibromatosis. Am J Ophthalmol 1991;1'i:729–734.
   Google Scholar
• Iraci G, Gerosa M, Tomayoli L, et al. Gliomas of the optic nerve and chiasm: a clinical review. Child's Brain 1981;8:326–349.
   PubMedGoogle Scholar
• Iraci G, Bertaggia A, Peserico L, et al. Spontaneous ('erosive') cerebrospinal rhinorrhea, with pneumococcal meningitis from anterior optic glioma. J Neurosurg Sci 1984;28:3–8.
   PubMedGoogle Scholar
• Jain NS. Two-stage intracranial and orbital operation for glioma of the optic nerve. Br J Ophthalmol 1961;45:54–58.
   PubMedGoogle Scholar
• Jakobiec FA, Depot MJ, Kennerdell JS, et al. Combined clinical and computed tomographic diagnosis of orbital glioma and meningioma. Ophthalmology 1984;91:137–155.
   PubMed Web of Science ®Google Scholar
• Janss AJ, Grundy R, Cnaan A, et al. Optic pathway and hypothalamic/ chiasmatic gliomas in children younger than age 5 years with a 6-year follow-up. Cancer 1995;75: 1052–1059.
   Web of Science ®Google Scholar
• Jenkin D, Angyalfi S, Becker L, et al. Optic glioma in children: surveillance, or irradiation? Int J Radiat Oncol Biol Phys 1993;25:215–225.
   PubMed Web of Science ®Google Scholar
• Kageyama N, Yoshida KJ, Sugita YK. Pathological considerations on follow-up results of optic glioma. Prog Exp Tumor Res 1987;30:100–107.
   Google Scholar
• Kanamori M, Shibuya M, Yoshida A, et al. Long-term follow-up patients with optic glioma. Child's Nerv Syst 1985;1:272–278.
   PubMed Web of Science ®Google Scholar
• Kelly TW. Optic glioma presenting as a spasmus nutans. Pediatrics 1970;45:295–296.
   PubMedGoogle Scholar
• Kestle JRW, Hoffman HJ, Mock AR. Moya moya phenomenon after radiation for optic glioma. J Neurosurg 1993;79:32–35.
   Google Scholar
• King DL, Chang CH, Pool IL. Radiotherapy in managment of meningiomas. Acta Radiol 1966;5: 26–33.
   Google Scholar
• Kingsley DPE, Kendall BE. CT of the adverse effects of therapeutic radiation of the central nervous system. J Neurol-radiol 1981;2:453–460.
   PubMed Web of Science ®Google Scholar
• Kinjo T, Mukawa J, Miyagi K, et al. Total removal of hypothalamic glioma 15 years after irradiation of right optic glioma. No Shinkei Geka 1991;19:1085–1086.
   PubMedGoogle Scholar
• Kocks W, Kalff R, Reinhardt V, et al. Spinal metastasis of pilocytic astrocytoma of the chiasma opticum. Child Nerv Syst 1982;5: 118–128.
   Web of Science ®Google Scholar
• Koenig SB, Naidich TP, Zaparackas Z. Optic glioma masquerading as spasmus nutans. J Pediatr Ophthalomol Strab 1982;19:20–24.
   PubMed Web of Science ®Google Scholar
• Kovalic JJ, Grigsby PW, Shepard MJ, et al. Radiation therapy for glioma of the optic nerve and chiasm. Int J Radiat Oncol Biol Phys 1990;18:927–932.
   PubMed Web of Science ®Google Scholar
• Kronlein RU. Zur Pathologie und operativen Behandlung der Dermoidcysten der Orbita. Beitr Klin Chir 1888;4:149–163.
   Google Scholar
• Kudo T. Spontaneous occlusion of the circle of Willis. A disease apparently confined to Japanese. Neurology 1968;18:485–496.
   Google Scholar
• Kupersmith MJ, Siegel JM, Carr RE, et al. Visual evoked potentials in chiasmal gliomas in four adults. Arch Neurol 1981;38:362–365.
   PubMedGoogle Scholar
• Lassman LP, Pearce GW, Gang J. Effect of vincristine sulfate on the intracranial gliomata of childhood. Br J Surg 1966;53:774–777.
   Google Scholar
• Laue L, Comite F, Hench K, et al. Precocious puberty associated with neurofibromatosis and optic gliomas. Am J Dis Child 1985;139:1097–I 100.
   Google Scholar
• Levin LA, Jakobiec FA. Optic nerve tumors of childhood: a decision-analytical approach to their diagnosis. Int Ophthalmol Clin 1992;32:223–240.
   PubMedGoogle Scholar
• Lewis RA, Gerson LP, Axelson KA, et al. Von Recklinghausen neurofibromatosis. II. Incidence of optic gliomata. Ophthalmology 1984;91:929–935.
   Google Scholar
• Listernick R, Charrow J, Greenwald MJ, et al. Optic gliomas in children with neurofibromatosis type I. J Pediatr 1989;114:788–792.
   PubMed Web of Science ®Google Scholar
• Listernick R, Charrow J, Greenwald M. Emergence of optic pathway gliomas in children with neurofibromatosis type I after normal neuroimaging results. J Pediatr 1992;121:584–587.
   Google Scholar
• Listernick R, Charrow J, Greenwald MJ, et al. Optic gliomas in children with neurofibromatosis type I. J Pediatr 1994;125:63–66.
   PubMed Web of Science ®Google Scholar
• Liu GT, Lessel S. Spontaneous visual improvement in chiasmal gliomas. Am J Ophthalmol 1992;114:193–201.
   PubMed Web of Science ®Google Scholar
• Lloyd GAS. Primary orbital meningioma: a review of 41 patients investigated radiologically. Clin
   Google Scholar
• Lloyd LA. Gliomas of the optic nerve and chiasm in childhood. Trans Am Ophthalmol Soc 1973;71: 488–535.
   PubMedGoogle Scholar
• Lourie GL, Osborne DR, Kirks DR. Involvement of posterior visual pathways by optic nerve gliomas. Pediatr Radiol 1986;16:271–274.
   Google Scholar
• Lowes M, Bojsen-Moller M, Hedegaard O. An evaluation of gliomas of the anterior visual pathways. A 10-year survey. Acta Neurochir 1978;43:201–216.
   PubMed Web of Science ®Google Scholar
• Lund AM, Skovby F. Optic gliomas in children with neurofibromatosis type 1. Eur J Pediatr 1991;150:835–838.
   PubMed Web of Science ®Google Scholar
• MacCarty CS, Boyd AS, Childs DS. Tumors of the optic nerve and optic chiasm. J Neurosurg 1970;33:439–444.
   Google Scholar
• MacDonnell P, Miller N. Chiasmatic and hypothalamic extension of optic nerve glioma. Arch Ophthalmol 1983;101:1412–1415.
   PubMedGoogle Scholar
• MacFadzean RM, Brewi TB, Doyle D, et al. Glioma of the optic chiasm and its management. Trans Ophthalmol Soc UK 1983;103:199–207.
   PubMedGoogle Scholar
• MacFarland PE, Eisenbeiss J. Glioma of optic nerve. Am J Ophthalmol 1950;33:463–466.
   Web of Science ®Google Scholar
• Maitland CG, Abiko S, Hoyt WF, et al. Chiasmal apoplexy. J Neurosurg 1982;56:118–122.
   PubMed Web of Science ®Google Scholar
• Mannheimer M. Glioma of the optic nerve. Am J Ophthalmol 1946;29: 323–328.
   PubMed Web of Science ®Google Scholar
• Manor RS, Israeli J, Sandbank U. Malignant optic glioma in a 70-year old patient. Arch Ophthalmol 1976;94: 1142–1144.
   Google Scholar
• Manshot WA. Primary tumors of the optic nerve in von Recklinghausen.s disease. Br J Ophthalmol 1954;38: 285–289.
   PubMed Web of Science ®Google Scholar
• Marks JE, Gado M. Serial computed tomography of primary brain tumors following surgery, irradiation, and chemotherapy. Radiology 1977;125:119–123.
   PubMed Web of Science ®Google Scholar
• Marquardt MD, Zimmerman LE. Histopathology of meningiomas and gliomas of the optic nerve. Hum Pathol 1982;13:226–235.
   PubMed Web of Science ®Google Scholar
• Marshall D. Glioma of the optic nerve as a manifestation of von Recklinghausen.s disease. Am J Ophthalmol 1954;37:15–36.
   PubMed Web of Science ®Google Scholar
• Martin P, Cushing H. Primary gliomas of the chiasm and optic nerves in their intracranial portion. Arch Ophthalmol 1923;52:209–241.
   Google Scholar
• Martins AN, Johnston JS, Henry JM, et al. Delayed radiation necrosis of the brain. J Neurosurg 1977;47: 336–345.
   PubMed Web of Science ®Google Scholar
• Matson DD. Neurosurgery of Infancy and Childhood, 2 ed. Springfield: Charles C. Thomas, 1969; 523.
   Google Scholar
• Mattson RH, Peterson EW. Glioblastoma multiforme of the optic nerve. J Am Med Assoc 1966;196:799–800.
   PubMed Web of Science ®Google Scholar
• McLoed AR. Acute blindness in childhood optic glioma caused by hematoma. J Pediatr Ophthalmol Strab 1983;20:31–33.
   PubMed Web of Science ®Google Scholar
• Meadows AT, Gordon S, Massari D, et al. Declines in IQ scores and cognitive dysfunction in children with acute lymphocytic leukemia treated with cranial irradiation. Lancet 1981;ii:1015–1018.
   Google Scholar
• Michel V. Ueber eine Hyperplasie des Chiasmas und des rechten Nervus opticus bei Eliphantiasis. Arch Ophthalmol 1873;19:145–164.
   Google Scholar
• Miller NR, Iliff WJ, Green WR. Evaluation and management of gliomas of the anterior visual pathways. Brain 1974;97:743–754.
   Google Scholar
• Miller NR. Orbital tumor. In: Long DM, editor. Current Therapy in Neurological Surgery. St. Louis: CV Mosby, 1985; 5–7.
   Google Scholar
• Moghrabi A, Friedman HS, Burger PC, et al. Carboplatin treatment of progressive optic pathway gliomas to delay radiotherapy. J Neurosurg 1993;79:223–227.
   PubMed Web of Science ®Google Scholar
• Montgomery AB, Griffin T, Parker RG, et al. Optic nerve glioma: the role of radiation therapy. Cancer 1977;40:2079–2080.
   PubMed Web of Science ®Google Scholar
• Myles ST, Murphy SB. Gliomas of the optic nerve and chiasm. Can J Ophthalmol 1973;8:508–514.
   PubMed Web of Science ®Google Scholar
• National Institutes of Health. Neurofibromatosis. National Institutes of Health Consensus Development Conference Statement. Bethesda, MD: The Institute, 1987; 6.
   Google Scholar
• Newman S. Spasmus nutans . or is it? Surv Ophthalmol 1990;34:453–456.
   PubMed Web of Science ®Google Scholar
• Nishio S, Taheshita I, Fujiwara S, et al. Optico-hypothalamic glioma: an analysis of 16 cases. Child.s Nerv Syst 1993;9:334–338.
   PubMed Web of Science ®Google Scholar
• North American Study Group for Optic Glioma. Tumor spread in unilateral optic glioma. Study Report No. 2. Neurofibromatosis 1989;2:195–203.
   PubMedGoogle Scholar
• Okuno T, Prensky AL, Gado M. The Moyamoya syndrome associated with irradiation of optic glioma in children: report of two cases and review of the literature. Pediatr Neurol 1985;1(311):316.
   Google Scholar
• Olivecrona H, Tonnis TC. Handbuch der Neurochirurgie. Berlin: Springer Verlag, 1967; 112–191.
   Google Scholar
• Ossoinig KC. A-scan echography and orbital disease. Mod Probl Ophthalmol 1975;4:203–235.
   Google Scholar
• Ossoinig KC. Standardized echography: basic principles, clinical applications, and results. Int Ophthalmol Clin 1979;19:127–210.
   PubMedGoogle Scholar
• Oxenhandler DC, Sayers MP. The dilemma of childhood optic gliomas. J Neurosurg 1978;48:34–41.
   PubMed Web of Science ®Google Scholar
• Packer RJ, Savino PJ, Bilaniuk LT, et al. Chiasmatic gliomas of childhood. A reappraisal of natural history and effectiveness of cranial irradiation. Child.s Brain 1983;10:393–403.
   Google Scholar
• Packer RJ, Bilaniuk LT, Cohen BH, et al. Intracranial visual pathway gliomas in children with neurofibromatosis. Neurofibromatosis 1988;1:212–222.
   PubMedGoogle Scholar
• Packer RJ, Sutton LN, Bilaniuk LT, et al. Treatment of chiasmal/ hypothalalmic gliomas of childhood with chemotherapy: an update. Ann Neurol 1988;23:79–85.
   PubMed Web of Science ®Google Scholar
• Packer RJ, Large B, Ater J, et al. Carboplatin and vincristine for recurrent and newly diagnosed lowgrade gliomas of childhood. J Clin Oncol 1993;11:850–856.
   PubMed Web of Science ®Google Scholar
• Packer RJ, Ater JC, Phillips P, et al. Efficacy of chemotherapy for children with newly diagnosed progressive low-grade gliomas(abstract). Ann Neurol 1994;36:496.
   Web of Science ®Google Scholar
• Panizza B. Annontazioni Anatomico-chirurgiche sul Fungo. Midollare dell.ochio. Pavia, Italia: Pietro Bizzoni, S. Bolzani, 1821.
   Google Scholar
• Parker JC, Smith JL, Reyes P, et al. Chiasmal optic glioma after radiation therapy. J Clin Neuroophthalmol 1981;1:31–43.
   PubMedGoogle Scholar
• Pascual-Castroviejo I, Verdu A, Roman M, et al. Optic glioma with progressive occlusion of the aqueduct of sylvius in monozygotic twins with neurofibromatosis. Brain Dev 1988;10:24–29.
   Google Scholar
• Patronas NJ, Dwyer AJ, Papathanasiou M, et al. Contributions of magnetic resonance imaging in the evaluation of optic glioma. Surg Ophthalmol 1987;28:367–371.
   Google Scholar
• Paulus WM, Brandt T, Kuhne D, et al. Therapie orbitaler und retroorbithler raumfordernder Prezesse mit Sehnervkompression. Nervenarzt 1983;50:519–534.
   Google Scholar
• Pelc S. The diencephalic syndrome in infants: a review on relation to optic nerve glioma. Eur Neurol 1972;7:321–334.
   PubMed Web of Science ®Google Scholar
• Petronio J, Edward MSB, Prados M, et al. Management of chiasmal and hypothalamic gliomas of infants and childhood with chemotherapy. J Neurosurg 1991;74:701–708.
   PubMed Web of Science ®Google Scholar
• Peyster RG, Hoover ED, Hershey BL, et al. High resolution CT of lesions of the optic nerve. Am J Radiol 1983;140:869–874.
   Google Scholar
• Pick A. On the study of true tumours of the optic nerve. Brain 1901;24:502–508.
   Google Scholar
• Pierce SM, Barnes PD, Loeffler JS, et al. Definitive radiation therapy in the management of symptomatic patients with optic glioma. Cancer 1990;65:45–52.
   PubMed Web of Science ®Google Scholar
• Potter GD, Trokel S. Tomography of the optic canal. Am J Roentgenol 1969;106:530–535.
   Web of Science ®Google Scholar
• Poujol J. Echographues de l.oeil et de l.orbite. Techniques echographues de diagnostic positif et differential. Causes d.erreurs et artifacts. Bull Soc Ophthalmol Fr P (Suppl) 1973;0:67–84.
   Google Scholar
• Price JL, Danzinger A. The computerized tomographic findings in paediatric orbital tumors. Clin Radiol 1979;30:435–440.
   PubMed Web of Science ®Google Scholar
• Rand CW, Irvine R, Reeves DL. Primary gliomas of the optic nerve. Arch Ophthalmol 1939;21:799–816.
   Google Scholar
• Rappaport R, Brauner R. Growth and endocrine disorders secondary to cranial irradiation. Pediatr Res 1989;25:561–567.
   PubMed Web of Science ®Google Scholar
• Redfern RM, Scholtz CL. Longterm survival with optic nerve glioma. Surg Neurol 1980;14:371–375.
   PubMedGoogle Scholar
• Reese AB. Tumors of the Eye, 3 ed. Hagerstown, MD: Harper and Row, 1976; 148–154.
   Google Scholar
• Repka MX, Miller NR. Optic atrophy in children. Am J Ophthalmol 1988;106:191–193.
   PubMed Web of Science ®Google Scholar
• Riccardi VM, Eichner JE. Neurofibromatosis: Phenotype, Natural History and Pathogenesis. Baltimore: Johns Hopkins University Press, 1986; 97.
   Google Scholar
• Richards RD, Lynn JR. The surgical management of gliomas of the optic nerve. Am J Ophthalmol 1966;62: 60–65.
   PubMed Web of Science ®Google Scholar
• Robertson AG, Brewin TB. Optic nerve glioma. Clin Radiol 1980;31: 471–474.
   PubMed Web of Science ®Google Scholar
• Rootman J. Diseases of the Orbit. A Multidisciplinary Approach. London: JB Lippincott Co., 1988; 281–285.
   Google Scholar
• Rosenstock JG, Audrey EE, Schut L. Response to vincristine of recurrent brain tumors in children. J Neurosurg 1976;45:135–140.
   Google Scholar
• Rosenstock JG, Packer RJ, Bilaniuk L, et al. Chiasmatic optic glioma treated with chemotherapy: a preliminary report. J Neurosurg 1985;63:862–866.
   PubMed Web of Science ®Google Scholar
• Rudd A, Rees JE, Kennedy P, et al. Malignant optic nerve gliomas in adults. J Clin Neuro Ophthalmol 1985;5:238–243.
   Web of Science ®Google Scholar
• Rush JA, Younge BR, Campbell RJ, et al. Optic glioma; long-term follow-up of 85 histologically verified cases. Ophthalmology 1982;89:1213–1239.
   PubMed Web of Science ®Google Scholar
• Russell A. A diencephalic syndrome of emaciation in infancy and childhood. Arch Dis Child 1951;26:274.
   Google Scholar
• Saebo J. Primary tumour of the optic nerve (glioblastoma multiforme). Br J Ophthalmol 1949;33:701–743.
   PubMed Web of Science ®Google Scholar
• Safneck JR, Napier LB, Halliday WC. Malignant astrocytoma of the optic nerve in a child. Can J Neurol Sci 1992;19:498–503.
   PubMed Web of Science ®Google Scholar
• Sanders GS, Allen RA, Straatsma BR. Arachoidal proliferation of optic nerve simulating extension of intracranial glioma. Arch Ophthalmol 1965;74:349–352.
   Google Scholar
• Sayli T, Cemeroglu AP, Tuncer AM. Acute lympoblastic leukemia following optic glioma treated by radiotherapy and surgery. Acta Paediatr 1993;82:327–328.
   Google Scholar
• Scarpa A. Trattato delle Principali Maletties degli Occhi, Quinta ed. Pavia: Pietro Bizzoni, 1816; 507–509.
   Google Scholar
• Schroeder W, Guthoff R. Ultrasonography of the optic nerve: results of measuring the dural diameter. Doc Ophthalmol Proc 1981;29:359–362.
   Google Scholar
• Schulman JA, Shults WT, Jones Jr JM. Monocular vertical nystagmus as an initial sign of chiasmal 199 glioma. Am J Ophthalmol 1979;87:87–90.
   Google Scholar
• Seiff SR, Brodsky MC, MacDonald G, et al. Orbital optic glioma in neurofibromatosis. Magnetic resonance diagnosis of perineural arachnoidal gliomatosis. Arch Ophthalmol 1987;105:1689–1692.
   Google Scholar
• Shapiro SK, Shapiro I, Wirtschafter JD. Malignant optic glioma in an adult: initial CT abnormality limited to the posterior orbit, leptom-eningeal seeding of the tumor. Minn Med 1982;65:155–159.
   Google Scholar
• Shields JA, Bakewell B, Augsburger JJ, et al. Classification and incidence of space-occupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol 1984; 102:1606–1611.
   PubMed Web of Science ®Google Scholar
• Shields JA. Diagnosis and Management of Orbital Tumors. Philadelphia: W.B. Saunders, 1989; 171.
   Google Scholar
• Shuper A, Horeu G, Kornreich L. Visual pathway glioma: an erratic tumour with therapeutic dilemmas. Arch Dis Child 1997;76:259–263.
   Google Scholar
• Skalka HW. Ultrasonography of the optic glioma. Neuro-ophthalmology 1981;1:261–272.
   Google Scholar
• Skalka HW, Kline LB. Comparative value of ultra-sound and CT in orbital optic nerve evaluation. Doc Ophthalmol Proc 1984;38:365–370.
   Google Scholar
• Sourdelle G. Les tumeurs nevrogliques adultes du nerf optique et retine. Arch Ophthalmol 1904;24:87–t00.
   Google Scholar
• Spencer WH. Primary neoplasms of the optic nerve and its sheaths: clinical features and current concepts of pathogenetic mechanisms. Trans Am Ophthalmol Soc 1972;70:490–528.
   PubMedGoogle Scholar
• Spencer WH. Diagnostic modalities and natural history of optic gliomas. Ophthalmology 1979;86:881–885.
   PubMed Web of Science ®Google Scholar
• Spitzer DD, Goodrich JT. Optic gliomas and neurofibromatosis: neurosurgical management. Neurofibromatosis 1988;I :223–232.
   Google Scholar
• Spoor TC, Kennerdell JS, Martinez AJ. Malignant gliomas of the optic nerve pathways. Am J Ophthalmol 1980;89:284–292.
   PubMed Web of Science ®Google Scholar
• Stern J, DiGiacinto GV, Housepian correlations. Neurosurgery 1979;4: 524–528.
   PubMed Web of Science ®Google Scholar
• Stern J, Jakobiec FA, Housepian EM. The architecture of optic nerve gliomas with and without neurofibromatosis. Arch Ophthalmol 1980;98:505–511.
   Google Scholar
• Sutton LN. Visual pathway gliomas of childhood. Neurosurgery 1994;16:1–6.
   Google Scholar
• Sutton LN, Molloy PT, Senyak H. Long-term outcome of hypothalamic/chiasmatic astrocytomas in children treated with conservative surgery. J Neurosurg 1995;83:583–589.
   Google Scholar
• Suzuki J, Takeuchi S. Cerebrovas-cular Moya-Moya disease. Arch Ophthalmol 1969;20:288–299.
   Google Scholar
• Swenson SA, Forbes GS, Younge BR, et al. Radiological evaluation of tumors of the optic nerve. Am J Neuro-radiol 1982;3:319–326.
   PubMed Web of Science ®Google Scholar
• Taphoorn MJB, de Vries-Knoppert WAEJ, Ponssen H, et al. Malignant optic nerve glioma in adults. J Neurosurg 1989;70:277–279.
   Google Scholar
• Tarbell NJ, Wallman J, Eifel P, et al. Results of definitive irradiation for optic gliomas. In: Walker MD, Thomas DGT, editors. Biology of Brain Tumors. Boston: Martinus Nijhoff Publishers, 1986; 373–379.
   Google Scholar
• Taveras JM, Mount LA, Wood EH. The value of radiation therapy in the management of gliomas of the optic nerves and chiasm. Radiology 1956;66:518–528.
   Google Scholar
• Tenney RT, Laws ER, Young BR, et al. The neurosurgical management of optic gliomas. Results in 104 patients. J Neurosurg 1982;57:452–458.
   PubMed Web of Science ®Google Scholar
• Thomsen OH. Undersogelser over degenerationen of nervus opticus Copenhagen. Cited in Hoyt et al.100
   Google Scholar
• Throuvalas N, Bataini P, Ennuyer A. Les gliomes du chasma et du nerf optique. L.apport de la radiotherapie trancutanee dans leur traitement. Bull Cancer (Paris) 1969;56:531–564.
   Google Scholar
• Trigg ME, Swanson JD, Letellier MA. Metastasis of an optic glioma through a ventriculoperitoneal shunt. Cancer 1983;52:599–601.
   Google Scholar
• Tym R. Piloid gliomas of the anterior optic pathways. Br J Surg 1961;49:322–331.
   PubMed Web of Science ®Google Scholar
• Udvahelyi GB, Khodadoust AA, Walsh FB. Gliomas of the optic nerve and chiasm in children; an unusual series of cases. Clin Neurosurg 1966;13:204–237.
   Google Scholar
• Venes JL, Latack J, Kandt RS. Postoperative regression of opticochiasmatic astrocytoma: a case for expectant therapy. Neurosurgery 1984;15:421–423.
   Google Scholar
• Verhoeff FH. Primary intraneural tumors (gliomas) of the optic nerve. A histologic study of eleven cases, including a case showing cystic involvement of the optic disk, with demonstration of the origin of cytoid bodies of the retina and cavernous atrophy of the optic nerve. Arch Ophthalmol 1922;51: 120–140.
   Google Scholar
• Verhoeff FH. Tumors of the optic nerve. In: Penfield A, editor. Cytology and Cellular Pathology of the Nervous System, Vol. 3. New York: Hoeber, 1932; 1029–1039.
   Google Scholar
• Visnot A, Rougerie J, Derome PJ, et al. Gliomes optochiasmatiques. Neurochirurgie 1990;26:181–192.
   Google Scholar
• von Graefe A. Zur Casuistik der Tumoren. Arch Ophthalmol 1984; 10:176–220.
   Google Scholar
• Wadswoth JAC. Surgical treatment of optic nerve tumors. South Med J 1969;62:871–874.
   PubMed Web of Science ®Google Scholar
• Wagener HP. Gliomas of the optic nerve. Am J Med Sci 1961;237: 238–261.
   Web of Science ®Google Scholar
• Walsh FB. The ocular signs of tumors involving the anterior visual pathways. The Tenth Francis I Proctor Lecture. Am J Ophthalmol 1956;42:347–377.
   PubMed Web of Science ®Google Scholar
• Weis L, Sagerman RH, King GA, et of optic nerve glioma. Cancer 1987;59:1000–1004.
   PubMed Web of Science ®Google Scholar
• White CP, Jan JE. Visual hallucinations after acute visual loss in a young child. Dev Med Child Neurol 1992;34:252–265.
   PubMed Web of Science ®Google Scholar
• Wilson GH, Byfield J, Hanafee WN. Atrophy following radiation therapy for central nervous system neoplasms. Acta Radiol (Stockh) 1972;11:361–368.
   Google Scholar
• Wilson JM, Farmer WD. Glioma of the optic nerve. A critical review: report of two cases with autopsy observations in one. Arch Ophthalmol 1940;27:605–618.
   Google Scholar
• Wilson WB, Finkel RS, McCleary L, et al. Large cystic optic glioma. Neurology 1900;40:1989–1900.
   Google Scholar
• Wilson WB, Fiensod M, Hoyt WF, et al. Malignant evolution of childhood chiasmal pilocytic astrocytoma. Neurology 1976;26:322–325.
   PubMed Web of Science ®Google Scholar
• Wishart JH. Case of extirpation of the eyeball. Edinburgh Med Surg 1833;40:274–276.
   PubMedGoogle Scholar
• Wisoff JH, Abbott R, Epstein F. Surgical management of exophytic chiasmatic-hypothalamic tumors of childhood. J Neurosurg 1990;73:661–667.
   Google Scholar
• Wisoff JH. Management of optic pathway tumors of childhood. Neurosurg Clin North Am a1992;3:791–802.
   PubMedGoogle Scholar
• Wong IG, Lobow M. Management of optic glioma of childhood-a review of 42 cases. In: Smith JL, editor. Neuro-ophthalmology Symposium of University of Miami and Bascom Palmer Eye Institute, Vol. VI. St. Louis: C.V. Mosby, 1972; 51–60.
   Google Scholar
• Wong JYC, Uhl V, Wara WM, et al. Optic gliomas. A reanalysis of the University of California, San Francisco experience. Cancer 1987;60:1847–1855.
   Google Scholar
• Wright JE, McDonald WI, Call NB. Management of optic nerve gliomas. Br J Ophthalmol 1980;64: 545–552.
   PubMed Web of Science ®Google Scholar
• Wright JE, McNab AA, McDonald WI. Primary optic sheath meningioma. Br J Ophthalmol 1989;73:960–966.
   PubMed Web of Science ®Google Scholar
• Wulc AE, Bergin DJ, Barnes MD, et al. Orbital optic nerve glioma in adult life. Arch Ophthalmol 1987;107:1013–1016.
   Google Scholar
• Yanoff M, Davis RL, Zimmerman LE. Juvenile pilocytic astrocytoma (.glioma.) of the optic nerve: clinicopathologic study of sixtythree cases. In: Jakobiec FA, editor. Ocular and Adnexal Tumors. Birmingham: Aesculapius, 1978; 685–707.
   Google Scholar