References

• BRACKETT, B. G., BARANSKA, W., SAVICKI, W. and KOPROWSKI, H. (1971). Uptake of heterologous genome by mammalian spermatozoa and its transfer to ova through fertilisation. Proceedings of the National Academy of Sciences, USA 68: 353–357.
   PubMed Web of Science ®Google Scholar
• BUMSTEAD, N., MESSER, L. I., FREEMAN, B. M. and MANNING, A. C. C. (1987a). Genetic transformation of chickens using irradiated male gametes. Heredity 58: 25–30.
   PubMed Web of Science ®Google Scholar
• BUMSTEAD, N., FREEMAN, B. M., MANNING, A. C. C. and HOWES, K. (1987b). Genetic transformation of chickens using irradiated sperm: co-transfer of undesirble genes. Avian Pathology 16: 417–424.
   PubMed Web of Science ®Google Scholar
• CRITTENDEN, L. B. (1986). Identification and cloning of genes for insertion. Poultry Science 65: 1468–1473.
   Web of Science ®Google Scholar
• CROWLEY, T. E., NELLEN, W., GOMER, R. H. and FIRTEL, R. A. (1985). Phenocopy of discoidin 1-minus mutants by antisense transformation of Dictyostelium. Cell 43: 633–641.
   PubMed Web of Science ®Google Scholar
• DAHAN, A., REYNAUD, C. A. and WEILL, J. C. (1983). Nucleotide sequence of the constant region of a chicken heavy chain immunoglobulin mRNA. Nucleic Acids Research 11: 5381–5389.
   PubMedGoogle Scholar
• DOEHMER, J., BARINAGA, M., VALE, W., ROSENFELD, M. G., VERMA, I. M. and EVANS, R. M. (1982). Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. Proceedings of the National Academy of Sciences, USA 79: 2268–2272.
   PubMed Web of Science ®Google Scholar
• FREEMAN, B. M. and BUMSTEAD, N. (1987). Breeding for disease resistance—the propective role of genetic manipulation. Avian Pathology 16: 353–365.
   PubMed Web of Science ®Google Scholar
• FREEMAN, B. M. and MESSER, L. I. (1985). Genetic manipulation of the domestic fowl—a review. World's Poultry Science Journal 41: 124–132.
   Web of Science ®Google Scholar
• GREEN, P. J., PINES, P. and INOUYE, M. (1986). The role of antisense RNA in gene regulation. Annual Review of Biochemistry 55: 569–597.
   PubMed Web of Science ®Google Scholar
• GROSS, W. G., SIEGEL, P. B., HALL, R. W., DOMERMUTH, C. H. and DUBOISE, R. T. (1980). Production and persistence of antibodies in chickens to sheep erythrocytes. 2. Resistance to infectious diseases. Poultry Science 59: 205–210.
   PubMed Web of Science ®Google Scholar
• HAMMER, R. E., PURSEL, V. G., REXROAD, C. E., WALL, R. J., BOLT, D. J., EBERT, K. M., PALMITER, R. D. and BRINSTER, R. L. (1985). Production of transgenic rabbits, sheep and pigs by microinjection. Nature, London 315: 680–683.
   PubMed Web of Science ®Google Scholar
• HUANG, A. L., OSTROWSKI, M. C., BERARD, D. and HAGER, G. L. (1981). Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences form mouse mammary tumor virus. Cell 27: 245–255.
   PubMed Web of Science ®Google Scholar
• HUGHES, S. H., KOSIK, E., FADLY, A. M., SALTER, D. W. and CRITTENDEN, L. B. (1986). Design of retroviral vectors for the insertion of foreign deoxyribonucleic acid sequences into the avian germ line. Poultry Science 65: 1459–1467.
   PubMed Web of Science ®Google Scholar
• IZANT, G. I. and WEINTRAUB, H. (1984). Inhibition of thymidine kinase gene expression by anti-sense RNA: a molecular approach to genetic analysis. Cell 36: 1007–1015.
   PubMed Web of Science ®Google Scholar
• IZANT, G. I. and WEINTRAUB, H. (1985). Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA. Science, New York 229: 345–352.
   Google Scholar
• JAHNER, D. and JAENISCH, R. (1980). Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation. Nature, London 287: 456–458.
   PubMed Web of Science ®Google Scholar
• JOYNER, A., YAMAMOTO, Y. and BERNSTEIN, A. (1982). Retroviral long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proceedings of the National Academy of Sciences, USA 79: 1573–1577.
   PubMed Web of Science ®Google Scholar
• JOYNER, A., KELLER, G., PHILLIPS, R. A. and BERNSTEIN, A. (1983). Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature, London 305: 556–558.
   PubMed Web of Science ®Google Scholar
• KIM, S. K. and WOLD, B. J. (1985). Stable expression of thymidine kinase activity in cells expressing high levels of anti-sense RNA. Cell 42: 129–138.
   PubMed Web of Science ®Google Scholar
• PALMITER, R. D., BRINSTER, R. L., HAMMER, R. E., TRUMBAUER, M. E., ROSENFELD, M. G., BRINBERG, N. C. and EVANS, R. M. (1982). Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature, London 300: 611–615.
   PubMed Web of Science ®Google Scholar
• PANDEY, K. K. and PATCHELL, M. R. (1982). Genetic transformation in chicken by use of irradiated male gametes. Molecular and General Genetics 186: 305–308.
   PubMedGoogle Scholar
• REYNAUD, C. A., DAHAN, A. and WEILL, J. C. (1983). Complete sequence of a chicken λ light chain immunoglobulin derived from the nucleotide sequence of its mRNA. Proceedings of the National Academy of Sciences, USA 80: 4099–4103.
   PubMed Web of Science ®Google Scholar
• ROWLETT, K. and SIMKISS, K. (1987). Explanted embryo culture: in vivo and in ovo techniques for domestic fowl. British Poultry Science 28: 91–101.
   Web of Science ®Google Scholar
• SALTER, D. W., SMITH, E. J., HUGHES, S. M., WRIGHT, S. E., FADLY, A. M., WITTER, R. L. and CRITTENDEN, L. B. (1986). Gene insertion into the chicken germ line by retroviruses. Poultry Science 65: 1445–1458.
   PubMed Web of Science ®Google Scholar
• SALTER, D. W., SMITH, E. J., HUGHES, S. H., WRIGHT, S. E. and CRITTENDEN, L. B. (1987). Transgenic chickens: insertion of retroviral genes into the chicken germ line. Virology 157: 236–240.
   PubMed Web of Science ®Google Scholar
• SCHNIEKE, A., HARBERS, K. and JAENISCH, R. (1983). Embryonic lethal mutation in mice induced by retrovirus insertion into the αl(1) collagen gene. Nature, London 304: 315–320.
   PubMed Web of Science ®Google Scholar
• SHIMOTOHNO, K. and TEMIN, H. M. (1981). Formation of infectious progeny virus insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus. Cell 26: 67–77.
   PubMed Web of Science ®Google Scholar
• SHUMAN, R. M. and SHOFFNER, R. N. (1986). Gene transfer by avian retroviruses. Poultry Science 65: 14376–1444.
   Web of Science ®Google Scholar
• SOLLER, M., HELLER, D., PELEG, B., RON-KUPER, N. and HORNSTEIN, K. (1981). Genetic and phenotypic correlations between immune response to Escherichia coli and to Newcastle disease virus vaccines. Poultry Science 60: 49–53.
   PubMed Web of Science ®Google Scholar
• STEPHENSON, M. L. and ZAMECNIK, P. C. (1978). Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proceedings of the National Academy of Sciences, USA 75: 285–288.
   PubMed Web of Science ®Google Scholar
• TABIN, C. J., HOFFMAN, J. W., CROFF, S. P. and WEINBERG, R. A. (1982). Adaption of a retrovirus as a eucaryotic vector transmitting the HSV thymidine kinase gene. Molecular and Cellular Biology 2: 426-.
   PubMed Web of Science ®Google Scholar
• WEI, C. M., SPEAR, P. G. and SCOLNICK, E. M. (1981). Construction and isolation of a transmissable retrovirus containing the src gene of Harvey immune sarcoma virus and the TK gene of herpes simplex type 1. Journal of Virology 39: 935–944.
   PubMed Web of Science ®Google Scholar
• YU, S-H., VON RINDEN, T., KANTOFF, P. W., GARBER, C., SEIBERG, M., RUTHER, U., ANDERSON, W. F., WAGNER, E. F. and GILBOA, E. (1986). Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Procedings of the National Academy of Sciences, USA 83: 3194–3198.
   PubMed Web of Science ®Google Scholar
• ZAMECNIK, P. C. and STEPHENSON, M. L. (1978). Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proceedings of the National Academy of Sciences, USA 75: 280–284.
   PubMed Web of Science ®Google Scholar