Analgesic effect of topical oral capsaicin gel in burning mouth syndrome

References

• Forssell H, Jääskeläinen S, Tenovuo O, et al. Sensory dysfunction in burning mouth syndrome. Pain. 2002;99:41–47.
   PubMed Web of Science ®Google Scholar
• Sun A, Wu KM, Wang YP, et al. Burning mouth syndrome: a review and update. J Oral Pathol Med.2013;42:649–655.
   PubMed Web of Science ®Google Scholar
• Grushka M, Epstein JB, Gorsky M. Burning mouth syndrome. Am Fam Physician. 2002;65:615–620.
   PubMed Web of Science ®Google Scholar
• Scala A, Checchi L, Montevecchi M, et al. Update on burning mouth syndrome: overview and patient management. Crit Rev Oral Biol Med. 2003;14:275–291.
   PubMedGoogle Scholar
• Pedersen AML, Smidt D, Nauntofte B, et al. Burning mouth syndrome: aetiopathogenic mechanisms, symptomatology, diagnosis and therapeutic approaches. Oral Biosci Med. 2004;1:3–19.
   Google Scholar
• de Moraes M, do Amaral Bezerra BA, da Rocha Neto PC, et al. Randomized trials for the treatment of burning mouth syndrome: an evidence-based review of the literature. J Oral Pathol Med.2012;41:281–287.
   PubMed Web of Science ®Google Scholar
• Forssell H, Jääskeläinen S, List T, et al. An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management. J Oral Rehabil. 2015;42:300–342.
   PubMed Web of Science ®Google Scholar
• Lauria G, Majorana A, Borgna M, et al. Trigeminal small-fiber sensory neuropathy causes burning mouth syndrome. Pain. 2005;115:332–337.
   PubMed Web of Science ®Google Scholar
• Albuquerque RJ, de Leeuw R, Carlson CR, et al. Cerebral activation during thermal stimulation of patients who have burning mouth disorder: an fMRI study. Pain. 2006;122:223–234.
   PubMed Web of Science ®Google Scholar
• Just T, Steiner S, Pau HW. Oral pain perception and taste in burning mouth syndrome. J Oral Pathol Med. 2010;39:22–27.
   PubMed Web of Science ®Google Scholar
• Puhakka A, Forssell H, Soinila S, et al. Peripheral nervous system involvement in primary burning mouth syndrome – results of a pilot study. Oral Dis. 2016;22:338–344.
   PubMed Web of Science ®Google Scholar
• Yilmaz Z, Renton T, Yiangou Y, et al. Burning mouth syndrome as a trigeminal small fibre neuropathy: increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score. J Clin Neurosci. 2007;14:864–871.
   PubMed Web of Science ®Google Scholar
• Mason L, Moore RA, Derry S, et al. Systematic review of topical capsaicin for the treatment of chronic pain. Bmj. 2004;328:991.
   PubMed Web of Science ®Google Scholar
• Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev. 1991;43:143–201.
   PubMed Web of Science ®Google Scholar
• Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet. 1999;353:1959–1964.
   PubMed Web of Science ®Google Scholar
• Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg. 2008;107:271–281.
   PubMed Web of Science ®Google Scholar
• Anand P, Bley K. Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch. Br J Anaesth. 2011;107:490–502.
   PubMed Web of Science ®Google Scholar
• Peikert A, Hentrich M, Ochs G. Topical 0.025% capsaicin in chronic post-herpetic neuralgia: efficacy, predictors of response and long-term course. J Neurol. 1991;238:452–456.
   PubMed Web of Science ®Google Scholar
• Epstein JB, Marcoe JH. Topical application of capsaicin for treatment of oral neuropathic pain and trigeminal neuralgia. Oral Surg Oral Med Oral Pathol. 1994;77:135–140.
   PubMedGoogle Scholar
• Petruzzi M, Lauritano D, De Benedittis M, et al. Systemic capsaicin for burning mouth syndrome: short-term results of a pilot study. J Oral Pathol Med. 2004;33:111–114.
   PubMed Web of Science ®Google Scholar
• Marino R, Torretta S, Capaccio P, et al. Different therapeutic strategies for burning mouth syndrome: preliminary data. J Oral Pathol Med. 2010;39:611–616.
   PubMed Web of Science ®Google Scholar
• Bernstein JE, Bickers DR, Dahl MV, et al. Treatment of chronic postherpetic neuralgia with topical capsaicin. A preliminary study. J Am Acad Dermatol. 1987;17:93–96.
   PubMed Web of Science ®Google Scholar
• Zakrzewska JM, Forssell H, Glenny AM. Interventions for the treatment of burning mouth syndrome. Cochrane Database Syst Rev. 2005;1:CD002779.
   Google Scholar
• McBurney DH, Balaban CD, Popp JR, et al. Adaptation to capsaicin burn: effects of concentration and individual differences. Physiol Behav. 2001;72:205–216.
   PubMed Web of Science ®Google Scholar
• Green BG, Rentmeister-Bryant H. Temporal characteristics of capsaicin desensitization and stimulus-induced recovery in the oral cavity. Physiol Behav. 1998;65:141–149.
   PubMed Web of Science ®Google Scholar
• Pedersen AM, Reibel J, Nauntofte B. Primary Sjögren's syndrome (pSS): subjective symptoms and salivary findings . J Oral Pathol Med. 1999;28:303–311.
   PubMed Web of Science ®Google Scholar
• Benedetti F, Mayberg HS, Wager TD, et al. Neurobiological mechanisms of the placebo effect. J Neurosci. 2005;25:10390–10402.
   PubMed Web of Science ®Google Scholar
• Yamazaki Y, Hata H, Kitamori S, et al. An open-label, noncomparative, dose escalation pilot study of the effect of paroxetine in treatment of burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:e6–e11.
   PubMed Web of Science ®Google Scholar
• Grushka M, Epstein J, Mott A. An open-label, dose escalation pilot study of the effect of clonazepam in burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;86:557–561.
   PubMed Web of Science ®Google Scholar
• Gremeau-Richard C, Woda A, Navez ML, et al. Topical clonazepam in stomatodynia: a randomised placebo-controlled study. Pain. 2004;108:51–57.
   PubMed Web of Science ®Google Scholar
• Femiano F, Gombos F, Scully C, et al. Burning mouth syndrome (BMS): controlled open trial of the efficacy of alpha-lipoic acid (thioctic acid) on symptomatology. Oral Dis. 2000;6:274–277.
   PubMed Web of Science ®Google Scholar
• Carbone M, Pentenero M, Carrozzo M, et al. Lack of efficacy of alpha-lipoic acid in burning mouth syndrome: a double-blind, randomized, placebo-controlled study. Eur J Pain. 2009;13:492–496.
   PubMed Web of Science ®Google Scholar
• Cavalcanti DR, da Silveira FR. Alpha lipoic acid in burning mouth syndrome – a randomized double-blind placebo-controlled trial. J Oral Pathol Med. 2009;38:254–261.
   PubMed Web of Science ®Google Scholar
• López-Jornet P, Camacho-Alonso F, Leon-Espinosa S. Efficacy of alpha lipoic acid in burning mouth syndrome: a randomized, placebo-treatment study. J Oral Rehabil. 2009;36:52–57.
   PubMed Web of Science ®Google Scholar
• Palacios-Sánchez B, Moreno-López LA, Cerero-Lapiedra R, et al. Alpha lipoic acid efficacy in burning mouth syndrome. A controlled clinical trial. Med Oral Patol Oral Cir Bucal. 2015;20:e435–e440.
   PubMed Web of Science ®Google Scholar
• Treldal C, Jacobsen CB, Mogensen S, et al. Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome. Oral Dis. 2016;22:123–131.
   PubMed Web of Science ®Google Scholar
• Burness CB, McCormack PL. Capsaicin 8 % patch: a review in peripheral neuropathic pain. Drugs. 2016;76:123–134.
   PubMed Web of Science ®Google Scholar
• Roberts LA, Connor M. TRPV1 antagonists as a potential treatment for hyperalgesia. Recent Pat CNS Drug Discov. 2006;1:65–76.
   PubMedGoogle Scholar