16
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Non-steroidal Anti-inflammatory Drugs Induce Apoptosis in Head and Neck Cancer Cell Lines

Pages 957-962 | Published online: 08 Jul 2009

  • Rosenberg L, Palmer JR, Zauber AG, Warshauer ME, Stolley PD, Shapiro S. A hypothesis: nonsteroidal antiinflammatory drugs reduce the incidence of large-bowel cancer. J Natl Cancer Inst 1991; 83: 355-8.
  • Smalley WE, Du Bois RN. Colorectal cancer and nonsteroidal antiinflammatory drugs. Adv Pharmacol 1997; 39: 1-20.
  • Giardiello FM, Offerhaus GJA, Du Bois RN. The role of non-steroidal anti-inflammatory drugs in colorectal cancer prevention. Eur J Cancer 1995; 31A: 1073-6.
  • Shiff SJ, Koutsos MI, Qiao L, Rigas B. Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. Exp Cell Res 1996; 222: 179-88.
  • Elder DJE, Hague A, Hicks DJ, Paraskeva C. Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumor cell lines: enhanced apoptosis in carcinoma and in vitro transformed adenoma relative to adenoma cell lines. Cancer Res 1996; 56: 2273-6.
  • Lu X, Fairbairn DW, Bradshaw WS, O'Neill KL, Ewert DL, Simmons DL. NSAID-induced apoptosis in Rous Sarcoma Virus-transformed chicken embryo fibroblasts is dependent on v-src and c-myc and is inhibited by bcl-2. Prostaglandins 1997; 54: 549-67.
  • Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456-62.
  • Gallo O, Bianchi S, Porfirio B. Bcl-2 overexpression and smoking history in head and neck cancer. J Natl Cancer Inst 1995; 87: 1024-5.
  • Gallo O, Boddi V, Calzolari A, Simonetti L, Trovati M, Bianchi S. Bcl-2 protein expression correlates with recurrence and survival in early stage head and neck cancer treated by radiotherapy. Clin Cancer Res 1996; 2: 261-7.
  • Saffron S, Gorogh T, Lippert BM, Werner JA. Kultivierung humaner oraler Keratinozyten des oberen Aerodigestivtraktes. Laryngorhinootologie 1997; 76: 101-5.
  • Strobl H, Takimoto M, Majdic O, et al. Meyeloperoxidase expression in CD34 + normal hematopoietic cells. Blood 1993; 82: 2069-78.
  • Rao CV, Rivenson A, Simi B, et al. Chemoprevention of colon carcinogensis by sulindac, a non steroidal anti-inflammatory agent. Cancer Res 1995; 55: 1464-72.
  • Piazza GA, Kulchak RAL, Krutzsch M, et al. Antineoplastic drug sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Cancer Res 1995; 55: 3110-6.
  • Stoll BA. Indomethacin in breast cancer. Lancet 1973; 2: 384.
  • Al-Salem T, AIi ZS, Quassab M. Skin cancer in Xeroderma pigmentosum response to indomethacin and steroids. Lancet 1980; 2: 264-5.
  • Chan G, Boyle JO, Yang EK, et al. Cyclooxygenase-2 expression is upregulated in squamous cell carcinoma of the head and neck. Cancer Res 1999; 59: 991-4.
  • Subbaramaiah K, Zakim D, Weksler BB, Dannenberg AJ. Inhibition of cyclooxygenases: A novel approach to cancer prevention. Proc Soc Exp Biol Med 1997; 216: 201-10.
  • Garavito RM. Improved non-steroid anti-inflammatory drugs: COX-2 enzyme inhibitors. London: Kluwer, 1996: 29-44.
  • Picot D, Loll PJ, Garavito RM. The X- ray crystal structure of the membrane protein prostaglandine H2 synthase. Nature 1994; 367: 243-9.
  • Chan AT, Morin JP, Vogelstein B, Kinzler WK. Mechanisms underlying nonsteroidal antiinflammatory drugmediated apoptosis. Proc Natl Acad Sci 1998; 85: 681-6.
  • Yin DX, Schimke RT. Bcl-2 expression delays drug induced apoptosis but does not increase clonogenic survivial after drug treatment in HeLa cells. Cancer Res 1995; 55: 4922-8.
  • Strasser A, Harris AW, Cory S. Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 1991; 67: 889-99.
  • Hawkins CJ, Vaux DL. Analysis of the role of Bcl-2 in apoptosis. Immunol Rev 1994; 142: 127-39.
  • SaIo A, Servomaa K, Kiuru A, et al. The bcl-2 gene status of human head and neck cancer cell lines. Acta Otolaryngol Suppl (Stockh) 1997; 529: 233-6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.