55
Views
69
CrossRef citations to date
0
Altmetric
Research Article

1,25(OH)2 Vitamin D3 Induces Elevated Expression of the Cell Cycle-regulating Genes P21 and P27 in Squamous Carcinoma Cell Lines of the Head and Neck

Pages 103-109 | Published online: 08 Jul 2009

References

  • Baker AR, McDonnell DP, Hughes M, et al. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci USA 1988; 85: 3294–8.
  • Pillai S, Bikle DD. Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: dif-ferences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3. J Cell Physiol 1991; 146: 94–100 .
  • Frampton RJ, Omond SA, Eisman JA. Inhibition of human cancer cell growth by 1,25-dihydroxyvitamin D3 metabolites. Cancer Res 1983; 43: 4443–7.
  • Olsson I, Gullberg U, Ivhed I, Nilsson K. Induction of differentiation of the human histiocytic lymphoma cell line U-937 by 1-alpha, 25-dihydroxycholecalciferol Cancer Res 1993; 43: 5862–7.
  • Bhalla AK, Amento EP, Serog B, Glimcher LH. 1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation. J Immunol 1984; 133: 1748–54.
  • Smith EL, Walworth NC, Holick MF. Effect of 1-al-pha, 25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epider-mal keratinocytes grown in serum-free conditions. J Invest Dermatol 1986; 86: 709–14.
  • Kornfehl J, Formanek M, Temmel A, Knerer B, Will-heim M. Antiproliferative effects of the biologically active metabolite of vitamin D3 (1,25[0El]2D3) on head and neck squamous cell carcinoma cell lines. Eur Arch Otorhinolaryngol 1996; 253: 341–4.
  • Nigg EA, Targets of cyclin-dependent protein kinases, Curr Opin Cell Biol 1993;5: 187–193.
  • MacLachlan TK, Sang N, Giordano A. Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer. Crit Rev Eukaryot Gene Express 1995; 5: 127–56.
  • Liu M, Lee MH, Cohen M, Bommakanti M, Freed-man LP. Transcriptional activation of the cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 1996; 10: 142–53.
  • Hisatake J, Kubota T, Hisatake Y, Uskokovic M, Tomoyasu S, Koeffler HP. 5,6-Trans-16-ene-vitamin D3: a new class of potent inhibitors of proliferation of prostate, breast, and myeloid leukemic cells. Cancer Res 1999; 59: 4023–9.
  • Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE. Normal keratinization in a spontaneously immortalized aneuploid human kerati-nocyte cell line. J Cell Biol 1988; 106: 761–71.
  • Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sherr CJ, Kato JY. D-type cyclin-dependent kinase activity in mammalian cells. Mol Cell Biol 1994; 14: 2066–76.
  • Sewing A, Barger C, Briisselbach S, Schalk C, Luci-bello FC, Muller R. Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. J Cell Sci 1993; 104: 545–54.
  • Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993; 366: 701–4.
  • Erber R, Klein W, Andl T, et al. Aberrant P21CIP11WAF1 protein accumulation in head-and-neck cancer. Int J Cancer (Pred Oncol) 1997; 74: 383–9.
  • Jares P, Fernández PL, Campo E, et al. PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryn-geal carcinomas. Cancer Res 1994; 54: 4813–7.
  • El-Deiry WS, Tokino T, Velculescu YE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817–25.
  • Min BM, Baek JH, Shin KH, et al. Inactivation of the p53 gene by either mutation or HPV infection is ex-tremely frequent in human oral squamous cell car-cinoma cell lines. Eur J Cancer Oral Oncol 1994; 30B: 338–45.
  • Zhang W, Grasso L, McClain CD, et al. p53-indepen-dent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying mono-cyte/macrophage differentiation. Cancer Res 1995; 55: 668–74.
  • Toyoshima H, Hunter T. p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 1994; 78: 67–74.
  • Wang QM, Jones JB, Studzinski GP. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. Cancer Res 1996; 56: 264–7.
  • Murphree AL, Benedict WF. Retinoblastoma: clues for human oncogenesis. Science 1984; 223: 1028–33.
  • Yoo GH, Xu HJ, Brennan JA, et al. Infrequent inacti-vation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res 1994; 54: 4603–6.
  • Loughran 0, Malliri A, Owens D, et al. Association of CDKN2A/p16INK4A with human head and neck kerati-nocyte replicative senescence: relationship of dysfunc-tion to immortality and neoplasia. Oncogene 1996; 13: 561–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.