212
Views
15
CrossRef citations to date
0
Altmetric
CENTRAL LABYRINTHINE PATHWAYS

Effects of hypergravity on histamine H1 receptor mRNA expression in hypothalamus and brainstem of rats: implications for development of motion sickness

, MD, , , , , , , & show all
Pages 45-51 | Received 09 Jan 2008, Published online: 08 Jul 2009

References

  • Igarashi M. Role of the vestibular end organs in experimental motion sickness: a primate model. Motion and space sickness, GH Crampton. CRC Press, Boca Raton, FL 1990; 43–8
  • Graybiel A, Wood CD, Knepton J, Hoche JP, Perkins GF. Human assay of anti-motion sickness drugs. Aviat Space Environ Med 1975; 46: 1107–18
  • Wood CD, Graybiel A. A theory of motion sickness based on pharmacological reaction. Clin Pharmacol Ther 1970; 11: 621–9
  • Takeda N, Hasegawa S, Morita M, Horii A, Uno A, Yamatodani A, et al. Neuropharmacological mechanisms of emesis. I. Effects of anti-emetic drugs on motion- and apomorphine-induced pica in rats. Methods Find Exp Clin Pharmacol 1995; 17: 589–96
  • Takeda N, Hasegawa S, Morita M, Matsunaga T. Pica in rats is analogous to emesis: an animal model in emesis research. Pharmacol Biochem Behav 1993; 45: 817–21
  • Takeda N, Horii A, Uno A, Morita M, Mochizuki T, Yamatodani A, et al. A ground-based animal model of space adaptation syndrome. J Vestib Res 1996; 6: 403–9
  • Horii A, Takeda N, Matsunaga T, Yamatodani A, Mochizuki T, Okakura-Mochizuki K, et al. Effect of unilateral vestibular stimulation on histamine release from the hypothalamus of rats in vivo. J Neurophysiol 1933; 70: 1822–6
  • Das AK, Yoshimura S, Miyoshi R, Fujimoto K, Mizuguchi H, Dev S, et al. Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription. J Pharmacol Sci 2007; 103: 374–82
  • Kitamura Y, Miyoshi Y, Murata Y, Kalubi B, Fukui H, Takeda N. Effect of glucocorticoid on up-regulation of histamine H1 receptor mRNA in nasal mucosa of rats sensitized by toluene diisocynate. Acta Otolaryngol 2004; 124: 1053–8
  • Horii A, Masumura C, Smith PF, Darlington CL, Kitahara T, Uno A, et al. Microarray analysis of gene expression in the rat vestibular nucleus complex following unilateral vestibular deafferentation. J Neurochem 2004; 91: 975–82
  • Haas H, Panula P. The role of histamine and tuberomammillary nucleus in the nervous system. Nat Rev Neurosci 2003; 4: 121–30
  • Morita M, Takeda N, Kubo T, Yamatodani A, Wada H, Matsunaga T. Effects of anti-motion sickness drugs on motion sickness in rats. ORL J Otolaryngol Relat Spec 1988; 50: 330–3
  • Calcutt CR, Ganellin CR, Griffiths R, Leigh BK, Maguire JP, Mitchell RC, et al. Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist. Br J Pharmacol 1988; 93: 69–78
  • Uno A, Takeda N, Horii A, Morita M, Kubo T, Yamamoto Y, et al. Histamine release from the hypothalamus induced by changes in gravity in rats and space motion sickness. Physiol Behav 1997; 61: 883–7
  • Wada H, Inagaki N, Yamatodani A, Watanabe T. Is the histaminergic neuron system a regulatory center for whole-brain activity?. Trends Neurosci 1991; 14: 415–18
  • Doig RK, Wolf S, Wolff HS. Study of gastric function in a decorticate man with gastric fistula. Gastroenterology 1953; 23: 40–4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.