271
Views
1
CrossRef citations to date
0
Altmetric
Research Article

The role of human papillomavirus in head and neck cancer and the impact on radiotherapy outcome

, , &
Pages 1291-1298 | Received 22 Apr 2016, Accepted 16 Jun 2016, Published online: 29 Jul 2016

References

  • Torre LA, Bray F, Siegel RL, Ferlay J, Joannie LT, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin 2015;65:87–108.
  • Cogliano VJ, Baan R, Straif K, Grosse TY, Béatrice LS, Fatiha E, et al. Preventable exposures associated with human cancers. J Natl Cancer Inst 2011;103:1827–39.
  • Fakhry C, Westra WH, Li SG, Cmelak A, Ridge JA, Pinto H, et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008;100:261–9.
  • Gillison ML, Koch WM, Capone RB. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 2000;92:709–20.
  • Ang KK, Harris J, Wheeler R, Weber R, Rosenthal DI, Nguyen PF, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 2010;363:24–35.
  • Kurdgelashvili G, Dores GM, Srour SA, Chaturvedi AK, Huycke MM, Devesa SS. Incidence of potentially human papillomavirus-related neoplasms in the United States, 1978 to 2007. Cancer 2013;119:2291–9.
  • Brian S, Shao HH, Bayardo PO, Christine M, Siud LL, Weinrebb IL, et al. Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionation. Radiother Oncol 2012;103:49–56.
  • Richard R. Human papillomavirus and survival of patients with oropharyngeal cancer. Child: Care, Health and Development 2010;363:24–35.
  • Barton MB, Jacob S, Shafiq J, Wong K, Thompson SR, Hanna TP, et al. Estimating the demand for radiotherapy from the evidence: a review of changes from 2003 to 2012. Radiother Oncol 2014;112:140–4.
  • Broglie MA, Soltermann A, Rohrbach D, Haile SR, Pawlita M, Studer G, et al. Impact of p16, p53, smoking, and alcohol on survival in patients with oropharyngeal squamous cell carcinoma treated with primary intensity-modulated chemoradiation. Head Neck 2013;35:1698–706.
  • Luciano MS, Lucyana CF, Carlos AD, Marcos VM, Cláudio MC, Thiago FS, et al. HPV-16/18 detection does not affect the prognosis of head and neck squamous cell carcinoma in younger and older patients. Oncol Lett 2012;3:945–9.
  • Sedghizadeh PP, Billington WD, Paxton D, Ebeed R, Mahabady S, Clark GT, et al. Is p16-positive oropharyngeal squamous cell carcinoma associated with favorable prognosis? A systematic review and meta-analysis. Oral Oncol 2016;54:15–27.
  • Marcu LG. Future treatment directions for HPV-associated head and neck cancer based on radiobiological rationale and current clinical evidence. Crit Rev Oncol Hematol 2016;103:27–36.
  • Dahlstrand HM, Lindquist D, Bjornestal L, Ohlsson A, Dallanis T, Wikland EM, et al. P16INK4a correlates to human papillomavirus presence, response to radiotherapy and clinical outcome in tonsillar carcinoma. Anticancer Res 2005;25:4375–83.
  • Chung CH, Zhang Q, Kong CS, Harris J, Fertig EJ, Harari PM, et al. P16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma. J Clin Oncol 2014;32:3930–8.
  • Lassen P, Eriksen JG, Hamilton-Dutoit S, Tramm T, Alsner J, Overgaard J. Effect of HPV-Associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck. J Clin Oncol 2009;27:1992–8.
  • Pajares B, Perez VL, Trigo JM, Toledo MD, Alvarez M, Jimenez B, et al. Concurrent radiotherapy plus epidermal growth factor receptor inhibitors in patients with human papillomavirus-related head and neck cancer. Clin Transl Oncol 2014;16:418–24.
  • Ritchie JM, Smith EM, Summersgill KF, Hoffman HT, Wang D, Klussmann JP, et al. Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx. Int J Cancer 2003;104:336–44.
  • Fakhry C, Zhang Q, Nguyen-Tan PF, Rosenthal D, El-Naggar A, Garden AS, et al. Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma. J Clin Oncol 2014;32:3365–73.
  • Huang H. Human papillomavirus infection and P16 protein expression in oropharyngeal squamous cell carcinoma and their clinical significance. [Doctoral dissertation]; 2012.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.