Advanced search
Publication Cover
Acta Oto-Laryngologica Volume 139, 2019 - Issue 1
Submit an article Journal homepage
288
Views
4
CrossRef citations to date
0
Altmetric
Research Article

The quantitative analysis of the human papillomavirus DNA load in submandibular gland lesions with droplet digital polymerase chain reaction

Ryuhei OkadaDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; View further author information
,
Taku ItoDepartment of Otorhinolaryngology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-8368-9573View further author information
ORCID Icon,
Fuminori NomuraDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; View further author information
,
Susumu KirimuraDepartment of Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, JapanView further author information
,
Yuichiro ChoDepartment of Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, JapanView further author information
,
Masaki SekineDepartment of Pathology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, JapanView further author information
,
Yumiko TateishiDepartment of Otorhinolaryngology, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; View further author information
,
Yosuke AriizumiDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; View further author information
&
Takahiro AsakageDepartment of Head and Neck Surgery, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan; View further author information
 show all
Pages 105-110 | Received 18 Oct 2018, Accepted 09 Dec 2018, Published online: 02 Feb 2019

References

  • Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363:24–35.
  • Rampias T, Sasaki C, Weinberger P, et al. E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells. J Natl Cancer Inst. 2009;101:412–423.
  • Klaes R, Friedrich T, Spitkovsky D, et al. Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 2001;92:276–284.
  • Chen ZW, Weinreb I, Kamel-Reid S, et al. Equivocal p16 immunostaining in squamous cell carcinoma of the head and neck: staining patterns are suggestive of HPV status. Head Neck Pathol. 2012;6:422–429.
  • Kreimer AR, Clifford GM, Boyle P, et al. Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev. 2005;14:467–475.
  • Vageli D, Sourvinos G, Ioannou M, et al. High-risk human papillomavirus (HPV) in parotid lesions. Int J Biol Markers 2007;22:239–244.
  • Brunner M, Koperek O, Wrba F, et al. HPV infection and p16 expression in carcinomas of the minor salivary glands. Eur Arch Otorhinolaryngol. 2012;269(10):2265–2269.
  • Huhns M, Simm G, Erbersdobler A, et al. HPV Infection, but Not EBV or HHV-8 infection, is associated with salivary gland tumours. Biomed Res Int. 2015;2015:829349.
  • Lin FC, Chen PL, Tsao TY, et al. Prevalence of human papillomavirus and Epstein-Barr virus in salivary gland diseases. J Int Med Res. 2014;42:1093–1101.
  • Atula T, Grenman R, Klemi P, et al. Human papillomavirus, Epstein-Barr virus, human herpesvirus 8 and human cytomegalovirus involvement in salivary gland tumours. Oral Oncol. 1998;34:391–395.
  • Skalova A, Kaspirkova J, Andrle P, et al. Human papillomaviruses are not involved in the etiopathogenesis of salivary gland tumors. Cesk Patol. 2013;49:72–75.
  • Descamps G, Duray A, Rodriguez A, et al. Detection and quantification of human papillomavirus in benign and malignant parotid lesions. Anticancer Res. 2012;32:3929–3932.
  • Miah MS, Majumdar S, White S, et al. Human papillomavirus and salivary gland neoplasia: a p16INK4 immunohistochemical and in situ hybridisation study. J Laryngol Otol. 2015;129:1000–1003.
  • Haeggblom L, Ursu RG, Mirzaie L, et al. No evidence for human papillomavirus having a causal role in salivary gland tumors. Diagn Pathol. 2018;13:44.
  • Nomura F, Sugimoto T, Kitagaki K, et al. Clinical characteristics of Japanese oropharyngeal squamous cell carcinoma positive for human papillomavirus infection. Acta Otolaryngol. 2014;134:1265–1274.
  • Kato Y, Peled N, Wynes MW, et al. Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J Thorac Oncol. 2010;5:1551–1558.
  • Jalouli M, Jalouli J, Ibrahim SO, et al. Comparison between single PCR and nested PCR in detection of human papilloma viruses in paraffin-embedded OSCC and fresh oral mucosa. In Vivo (Athens, Greece) 2015;29:65–70.
  • Biron VL, Kostiuk M, Isaac A, et al. Detection of human papillomavirus type 16 in oropharyngeal squamous cell carcinoma using droplet digital polymerase chain reaction. Cancer 2016;122:1544–1551.
  • Antonsson A, Knight L, Panizza BJ, et al. HPV-16 viral load in oropharyngeal squamous cell carcinoma using digital PCR. Acta Otolaryngol. 2018;138:1–5.
  • Jalouli J, Ibrahim SO, Sapkota D, et al. Presence of human papilloma virus, herpes simplex virus and Epstein-Barr virus DNA in oral biopsies from Sudanese patients with regard to toombak use. J Oral Pathol Med. 2010;39:599–604.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.